DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ntl and si:ch211-283g2.1

DIOPT Version :9

Sequence 1:	NP_609135.1	Gene:	Ntl / 34046	FlyBaseID:	FBgn0267326	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	XP_017211707.1	Gene:	si:ch211-283g2.1 / 569007	ZFINID:	ZDB-GENE-060531-57	Length:	581	Species:	Danio rerio

Alignment Length:	558	Identity:	210/558 - (37%)
Similarity:	338/558 - (60%)	Gaps:	17/558 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 ERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVILAGIPLFYMEIL 83
            :.:..|..|..:.||.|:.:|.|:|:||:||||||||||||.|||:|||||:::.||||.:||:.
Zfish     4 KEEAGRPTWSRQIEFTLAGIGCAVGLGNIWRFPYLCYRSGGGAFLLPYLLMLVVLGIPLLHMELT 68

  Fly    84 IGQFSSTG-CTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCFFKKVPWEDCSNS 147
            :||:...| ...:.:..||.||.|:|.|.::.....||::||::.:..:|..|..::.|::|:|:
Zfish    69 LGQYLRRGPVLALAKACPLFKGVGMATVAISFIMCTYYNIIITWALYYMFSSFRSELLWQNCNNT 133

  Fly   148 WNTDDCVTASDMGKQNSSDVFKTSADEFFHLEVLRISTDISDLGGMVWEQLTALIITWIIIYFCL 212
            |||.:|   :|....:||.  .|::.:||:.:||..::.:.:.|.:.||....|::.||::|.|:
Zfish   134 WNTVNC---TDQVTNSSSS--STASQQFFNYKVLERTSGVEETGTLRWELFLLLLLAWILVYLCI 193

  Fly   213 MRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYPEWHRLLDLKVWADAAVQMFF 277
            .:|:||.|||||||..|||::|..|||....||||..||||::.|||.:||:::||.:||.|:|.
Zfish   194 FKGVKSTGKVVYFTALFPYVILLALLINNVQLPGALDGIKFFIIPEWDKLLNVQVWINAAAQIFN 258

  Fly   278 GIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLGFLSEKSGIPVESVATG 342
            .||.|:|.::.|||::::.||...|::.|...|..||:.||||:||..|::|....:||..:|..
Zfish   259 SIGIGFGSLMAMASYNNYNNNVLKDTLAIAITNSLTSIFAGFVIFSAFGYMSHLQNVPVSEIAVD 323

  Fly   343 GAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAIMSSILDEW------YWVRSH 401
            |.||..|.||:|...:||..|||.:|||||..||:||.|..:|.:::|:||.:      :..|..
Zfish   324 GPGLVLVVYPQAFVTMPVAPLWAFLFFFMLLCLGLDSQFAMVEVMVTSLLDSYSKPILKHLKRKE 388

  Fly   402 KCKLTLISCLIFLGLSSIMCTNGGMFILQLFDWYSSAIAVIVICLVEIIMVAWIYGIKNFMLDVE 466
            ...|.:......||:.::|  ..|:::.||.|.|::.::::.:...|::.|.|.||:|....::.
Zfish   389 FLVLLVCGAAFLLGIPNVM--QVGIYVFQLMDHYTAIVSIMFLAFFEVVGVCWCYGVKRLSSNLV 451

  Fly   467 FMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFIRTITYNNIPYPQWAIIIGWASCFTSVMWIPL 531
            .|.||||::::||.|.|:.|.:|..||:.|::..:...|.:..||.||..:||.....|::||||
Zfish   452 EMTGKRPSIFFRICWWVICPALITVILVFSVIQFKPARYEDYVYPPWAQGVGWLIALASIIWIPL 516

  Fly   532 YIFYIMIRKRATLCDSLKKRLKPLDWTPADPQDRAEYE 569
            ...:.:.....:..:..||.:.|..   .|..|...|:
Zfish   517 AAVHTLWVLPGSFTEKFKKSITPFS---LDEDDSPYYQ 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:294310	206/536 (38%)
si:ch211-283g2.1	XP_017211707.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920