Protein Alignment Ntl and slc6a15

DIOPT Version :10

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001232001.1
• Gene: slc6a15 / 565315
• ZFINID: ZDB-GENE-050420-93
• Length: 741
• Species: Danio rerio
• Alignment Length: 614
• Identity: 187/614 - (30%)
• Similarity: 318/614 - (51%)
• Gaps: 105/614 - (17%)

  Fly     3 NNQPPTTNATRKDKRIERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYL 67
            |.|......:.:::. |.:|.|..|.||.::||:.:|:::|:||||||||||.::||.|:|:|||
Zfish    48 NKQKDVEEGSEEEEE-EEEEERPAWGSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLVPYL 111

  Fly    68 LMVILAGIPLFYMEILIGQFSSTGCTGMFR-MTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMI 131
            ::::|.|||||::|:.:||....|..|::. ::|.|.|.|.|..:|..:...||:|||.:.:...
Zfish   112 ILLLLIGIPLFFLELAVGQRIRRGSIGVWNYISPHLGGIGFASCLVCFFVALYYNVIIGWSLFYF 176

  Fly   132 FYCFFKKVPWEDC------SNSWNTDDCVTASDMGKQNSSDVFKTSADEFFHLEV-LRISTDISD 189
            ...|.:.:||.:|      :|::...:|.              |:||..::...| |.||..||:
Zfish   177 SQSFQQPLPWHECPLVKNKTNTYIEPECE--------------KSSATTYYWYRVALDISDSISE 227

  Fly   190 LGGMVWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFY 254
            .||:.|.....|:..|.::...:::||:|.|||:||:..|||::|...|.|...|.|:..||...
Zfish   228 GGGLNWRMTLCLLAAWTMVCLAMIKGIQSSGKVMYFSSLFPYVVLICFLARAFLLKGSVDGIIHM 292

  Fly   255 LYPEWHRLLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGF 319
            ..|:...:|:.|||.:||.|:||.:|.|:||::..:|::...||...|:||:..||.|||:||..
Zfish   293 FTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATL 357

  Fly   320 VVFSVLGFLSEKSG-----------------------IP-------------------VESV--- 339
            |||:||||.:....                       ||                   ::.|
Zfish   358 VVFAVLGFKANIMNAKCVEMNTKKIIGFLGKEINPGLIPHHINFSQVSPEDYQQMTNIIQGVMEN 422

  Fly   340 ------------------ATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEA 386
                              |..|.||||:.:.||:...|....|::|||.||..||:.|:|..::.
Zfish   423 DYPRLGLDNCDIKEELNKAVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIQG 487

  Fly   387 IMSSILDEWYWVRSHKCKLTLISCLI--FLGLSSIMCTNGGMFILQLFDWYSSAIAVIVICLVEI 449
            |::.|:|.:   :..|..||:..|::  |:||:.:.  ..|.:.:.:||.||:.:.::::.|:|.
Zfish   488 ILTPIVDTF---KVRKEYLTVGCCVLAFFIGLTFVQ--RSGNYFVAMFDDYSATLPLLIVVLLEN 547

  Fly   450 IMVAWIYGIKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFI------------RT 502
            |.|||:||...|..|::.|||..|..|:..:|:.||||:::.:|..|::.:            :.
Zfish   548 IAVAWVYGTDKFFEDLKDMLGFTPYRYYYYMWKFVTPVLLLGLLAASVIQLGLAPPSYSAWNQQL 612

  Fly   503 ITYNNIPYPQWAIIIGWASCFTSVMWIPL 531
            ....::.||.|.:.:..:...|:::.:|:
Zfish   613 AKEQSLSYPPWGLAVCISLVVTAILPVPV 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	183/593 (31%)
slc6a15	NP_001232001.1	SLC5-6-like_sbd	68..646	CDD:444915	183/593 (31%)