Protein Alignment Ntl and slc6a7

DIOPT Version :10

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001074049.1
• Gene: slc6a7 / 562050
• ZFINID: ZDB-GENE-070112-1492
• Length: 537
• Species: Danio rerio
• Alignment Length: 509
• Identity: 189/509 - (37%)
• Similarity: 298/509 - (58%)
• Gaps: 35/509 - (6%)

  Fly    69 MVILAGIPLFYMEILIGQFSSTGCTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFY 133
            |:...|:|||.||:.:||:.:.|...:::..|||||.||..:.|:.....||:|||::....:..
Zfish     1 MLFFTGMPLFLMELSLGQYGAAGPITVWKCCPLLKGIGIGMLCVSTLVCLYYNVIIAWTFYYLGS 65

  Fly   134 CFFKKVPWEDCSNSWNTDDCVTASDMGKQNSSDVFKTSADEFFHLEVLRI--STDISDLGGMVWE 196
            .|...:|| .|....|...|.     .|.||:   ::.::.|::.:||.:  ||.:||.|.:.|.
Zfish    66 SFQSPLPW-SCDALQNIALCA-----NKTNST---QSPSEVFWNEKVLGVVHSTGLSDPGPVRWP 121

  Fly   197 QLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYPEWHR 261
            ....|:..||||:.|:::||.|.|||||.|..|||.:|.:|:||||||.|:..|:.|||.|:|.:
Zfish   122 LALCLLAAWIIIFLCMLKGIHSSGKVVYLTATFPYFVLLVLIIRGATLEGSLDGVAFYLTPKWDQ 186

  Fly   262 LLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLG 326
            |.|.:||.|||.|:|:.:|.|.||:::|||::.|.||...|:::|...|..||..|||.:||:||
Zfish   187 LADAQVWNDAASQIFYSLGIGVGGLLSMASYNKFDNNVIRDTIIITIGNCSTSFFAGFAIFSILG 251

  Fly   327 FLSEKSGIPVESVATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAIMSSI 391
            .::.|.|:||:.||..|.|||||.||||:||||....|:::||.|||:||:|::|..:|.|.:::
Zfish   252 HMAFKKGVPVDKVADSGPGLAFVAYPEALALLPGSVFWSILFFLMLFMLGVDTLFGNMEGICTAV 316

  Fly   392 LDEWYWVRS---HKCKLTLISCLIFLGLSSIMCTNGGMFILQLFDWYSSAIAVIVICLVEIIMVA 453
            |||:..:||   ||.....:.|..|..:..::.|:||::...|.|.:|::..:|:|.|...|.::
Zfish   317 LDEFPQLRSNLKHKTLFLAVLCFSFYLMGLLLITDGGIYWFTLIDSFSTSFGLIIITLFMCIGIS 381

  Fly   454 WIYGIKNFMLDVEFMLGKRP------TLYWRIVWQVVTPVIIIFILITSIVFIR----TITYNNI 508
            :.||:..|..|:..|:.:.|      .||::..|.|.||.::.|||  :.:||.    ::.|.:.
Zfish   382 FFYGVNQFCQDIVDMICRCPPWCTKMLLYFKACWVVFTPFLLTFIL--TYIFIEMYRTSLRYGSY 444

  Fly   509 PYPQW----AIIIGWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLKPLD-W 557
            .||.|    .:.:|...|...::|..:.|    .::..||.|..||.::||: |
Zfish   445 VYPIWGKALGVCMGALCCLQILIWAIVAI----SKESGTLKDRFKKSIRPLNSW 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	186/503 (37%)
slc6a7	NP_001074049.1	SLC5-6-like_sbd	1..495	CDD:444915	189/509 (37%)