Protein Alignment Ntl and slc6a6a

DIOPT Version :9

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001119858.1
• Gene: slc6a6a / 556480
• ZFINID: ZDB-GENE-081104-1
• Length: 625
• Species: Danio rerio
• Alignment Length: 566
• Identity: 219/566 - (38%)
• Similarity: 358/566 - (63%)
• Gaps: 20/566 - (3%)

  Fly     6 PPTTNATRKDKRIE-RDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLM 69
            |..:..||.:...| :...|.:|.||.:|:||:.|..:|:|||||||||||::||.||||||.:.
Zfish    22 PGKSPGTRPEDEAEGKAPQREKWASKLDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIF 86

  Fly    70 VILAGIPLFYMEILIGQFSSTG---CTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMI 131
            :...|:|:|::|:.:|||:|.|   |.|  ::.|:..|.|.|.:::.:....||.||:::.:..:
Zfish    87 LFGGGLPVFFLEVALGQFTSEGGITCWG--KLCPIFTGIGYASIIIVSLLNIYYIVILAWGLYYL 149

  Fly   132 FYCFFKKVPWEDCSNSWNTDDCVTASDMGKQN-------SSDVFKTSADEFFHLEVLRISTDISD 189
            ..||..::||..|.:||||::||  .|..::|       ::..|.:...||:...||.||:.|.:
Zfish   150 LQCFQHELPWARCRHSWNTENCV--EDTVRKNKTLWLSANATNFTSPVTEFWERNVLSISSGIDE 212

  Fly   190 LGGMVWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFY 254
            :||:.||....|:..|:|.:||:.:|:||.|||||||..||:|:|.:|||||.|||||.:|||||
Zfish   213 VGGLKWELALCLLAVWVICFFCIWKGVKSTGKVVYFTATFPFLMLIVLLIRGVTLPGATEGIKFY 277

  Fly   255 LYPEWHRLLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGF 319
            |||:..||.|.:||.||..|:||......|.:.::.|::.::.|...|.:|:..:|..||.::||
Zfish   278 LYPDLSRLKDPEVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNCYRDCMLLGCLNSGTSFVSGF 342

  Fly   320 VVFSVLGFLSEKSGIPVESVATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQL 384
            .:||||||::::.||.:..||..|.||||:.||:|:.::|:|.:||::||.||.|||:||.||::
Zfish   343 AIFSVLGFMAQEQGIAIADVAESGPGLAFIAYPKAVTMMPLPTVWAILFFIMLLLLGLDSQFVEV 407

  Fly   385 EAIMSSILDEWYWV--RSHKCKLTL-ISCLIFLGLSSIMCTNGGMFILQLFDWY-SSAIAVIVIC 445
            |..::|::|.:..:  :.::.::.: :.|:|...|...|.|.|||::.||||:| :|.:.::.:.
Zfish   408 EGQITSLVDLYPSLLRKGYRREIFIAVICVISYLLGLTMVTKGGMYVFQLFDYYAASGVCLLWVA 472

  Fly   446 LVEIIMVAWIYGIKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFIRTITYNNI-P 509
            ..|.:.|||:||..||...:|.|:|.||..:.:..|.::|||:.:...:.|:|..:.:|||.: .
Zfish   473 FFECVAVAWVYGADNFYDAIEDMIGYRPNSWMKWSWMLITPVLCVGCFVFSLVKYKPLTYNKLYK 537

  Fly   510 YPQWAIIIGWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLKPL 555
            ||.|:|.:|||....|::.||:.:...:|:...:|.:.:|....|:
Zfish   538 YPDWSIGLGWALALASMICIPMMVVIKIIQSDGSLIERIKAVAAPV 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:294310	214/544 (39%)
slc6a6a	NP_001119858.1	SLC6sbd_TauT	41..582	CDD:271398	214/544 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920