Protein Alignment Ntl and slc6a1b

DIOPT Version :10

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001007363.1
• Gene: slc6a1b / 492490
• ZFINID: ZDB-GENE-041114-57
• Length: 600
• Species: Danio rerio
• Alignment Length: 565
• Identity: 221/565 - (39%)
• Similarity: 355/565 - (62%)
• Gaps: 30/565 - (5%)

  Fly     4 NQPPTTN--------ATRKDKRIERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGA 60
            |:.||.|        ..:|.|.:   .:|..|:.|.:|:||.:|||||:||||||||||.::||.
Zfish    18 NEAPTANDKPKTLVVKVQKKKEL---PDRETWQGKFDFLLSCVGYAIGLGNVWRFPYLCGKNGGG 79

  Fly    61 AFLIPYLLMVILAGIPLFYMEILIGQFSSTGCTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIIS 125
            ||||||.|.:|.||:|||::|..:||::|.|..|::::.|:.||.|:|..|::.:...||.|||:
Zfish    80 AFLIPYFLTLIFAGVPLFFLETALGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIIA 144

  Fly   126 YPIRMIFYCFFKKVPWEDCSNSWNTDDC---VTASDMGKQNSSDVFKTSADEFFHLEVLRISTDI 187
            :.|..::..|...:||:.|.|.||||.|   .:.:::|...|:.|      ||:...:.:::..:
Zfish   145 WAIYYLYNSFTTDLPWKSCDNPWNTDKCFSNYSMANIGNMTSAVV------EFWERNMHQLTDGL 203

  Fly   188 SDLGGMVWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIK 252
            ...|.:.......|.|.|:::|||:.:|:...||||||:..:||.:||||.|||.|||||.:||.
Zfish   204 EKPGEIRLPLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATYPYFMLFILFIRGVTLPGAKEGIL 268

  Fly   253 FYLYPEWHRLLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLA 317
            ||:.||:.:|.:.:||.|||.|:||..|.|.|.::.:.|::.|.||...||:::..||.|||:.|
Zfish   269 FYVTPEFSKLKESEVWLDAATQIFFSYGLGLGSLIALGSYNPFNNNVYKDSIIVCCINSFTSMFA 333

  Fly   318 GFVVFSVLGFLSEKSGIPVESVATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFV 382
            |||:||::||::..:..|:..||..|.||||:.||||:..||:..|||::||.||.:|||||.|.
Zfish   334 GFVIFSIVGFMAHITKRPIADVAASGPGLAFLAYPEAVTQLPISPLWAVLFFSMLLMLGIDSQFC 398

  Fly   383 QLEAIMSSILDEW-YWVRSHKCKLTLISCLI--FLGLSSIMCTNGGMFILQLFDWYS-SAIAVIV 443
            .:|..:::::||: ..:|..:.....:.||:  .:|||:|  |.||:::.:|||:|| |.:.::.
Zfish   399 TVEGFITALVDEFPRALRGRREIFIAVVCLVSYLIGLSNI--TQGGLYVFKLFDYYSASGMCLLF 461

  Fly   444 ICLVEIIMVAWIYGIKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFIRTITYNNI 508
            :...|.:.::|.||:..|..::|.|:|.:|.::|::.|.|.||:|:..:.:.|.|.:..:|.||.
Zfish   462 LVFFECVSISWFYGVNKFYGNLEEMIGYKPCIWWKLCWVVFTPLIVAGVFLFSAVQMVPLTLNNY 526

  Fly   509 PYPQWAIIIGWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLK 553
            .:|:|...:||....:|::.||.|:.|:.:    ||..|.|:||:
Zfish   527 VFPKWGQGVGWCMALSSMVLIPGYMGYMFL----TLKGSYKERLR 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	215/537 (40%)
slc6a1b	NP_001007363.1	SLC5-6-like_sbd	2..600	CDD:444915	221/565 (39%)