Protein Alignment Ntl and Gat

DIOPT Version :9

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Alignment Length: 603
• Identity: 230/603 - (38%)
• Similarity: 364/603 - (60%)
• Gaps: 34/603 - (5%)

  Fly     1 MANNQPPTTNATRKDK--RIERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFL 63
            :.::.|.||:.:.|.:  :||:..:||.|.||.:||||::|.|||:|||||||||||::||.||:
  Fly    33 LQSSSPTTTDTSNKQQLVKIEQLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFI 97

  Fly    64 IPYLLMVILAGIPLFYMEILIGQFSSTGCTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPI 128
            :||::.:.|||||:|:||:.:||..:.|..|:|::.|:.||.|.|..|::.:...||.||:::.:
  Fly    98 LPYIITLFLAGIPMFFMELALGQMLTIGGLGVFKIAPIFKGIGYAAAVMSCWMNVYYIVILAWAV 162

  Fly   129 RMIFYCFFKKVPWEDCSNSWNTDDCVTASDMGKQN-----------SSDVFKTSA---------- 172
            ...|......|||..|:|.|||.:||  |...::|           :..|...||
  Fly   163 FYFFMSMRADVPWRTCNNWWNTVNCV--SQYERKNLHCWDKIINGTTQKVCSVSALNITSLELTD 225

  Fly   173 --DEFFHLEVLRISTDISDLGGMVWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLF 235
              .||:....|:||..|.::|.:.||....|::.||:.|||:.:|:|..|||||||..|||:||.
  Fly   226 PVKEFWERRALQISHGIEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLT 290

  Fly   236 ILLIRGATLPGAWKGIKFYLYPEWHRLLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAK 300
            |||:||.|||||.:|||||:.|.:.:|.:.:||.||..|:||..|.|.|.:|.:.|::.|.||..
  Fly   291 ILLVRGITLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVY 355

  Fly   301 CDSVLIVSINVFTSLLAGFVVFSVLGFLSEKSGIPVESVATGGAGLAFVTYPEAIALLPVPQLWA 365
            .|::::.::|..||:.||||:|||:||::.:...||..||..|.||||:.||.|:..||...:|:
  Fly   356 KDALIVCTVNSSTSMFAGFVIFSVIGFMAHEQQRPVADVAASGPGLAFLVYPSAVLQLPGSPMWS 420

  Fly   366 LMFFFMLFLLGIDSVFVQLEAIMSSILDEW-YWVRSHKCKLTLISCLI--FLGLSSIMCTNGGMF 427
            .:|||||.|:|:||.|..:|..:::|:||| ..:|..|.....|.|.:  .:||:.|  |.|||:
  Fly   421 CLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIAIVCALSYLVGLTCI--TQGGMY 483

  Fly   428 ILQLFDWYS-SAIAVIVICLVEIIMVAWIYGIKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIF 491
            |.|:.|.|: |...::.:...|.:.::|.||:..|...::.|:|..||::|:..|.|.||.|.:.
  Fly   484 IFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIGYYPTVWWKFCWCVTTPAICLG 548

  Fly   492 ILITSIVFIRTITYNNIPYPQWAIIIGWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLKPLD 556
            :...:||....:.|.:..||.||...||.:..:|:::||||:|::..|....|.:.::..:: :|
  Fly   549 VFFFNIVQWTPVKYLDYSYPWWAHAFGWFTALSSMLYIPLYMFWLWKRTPGELSEKIRALVR-ID 612

  Fly   557 WTPADPQDRAEYEAFRRQ 574
            ......:::...||:.::
  Fly   613 EDVTRLREKMLREAYAKE 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:294310	221/556 (40%)
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	221/557 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440717
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2610
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.800