Protein Alignment Ntl and Slc6a16

DIOPT Version :9

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001311464.1
• Gene: Slc6a16 / 381884
• MGIID: 2685930
• Length: 742
• Species: Mus musculus
• Alignment Length: 612
• Identity: 156/612 - (25%)
• Similarity: 275/612 - (44%)
• Gaps: 112/612 - (18%)

  Fly    17 RIERDENRGQ-----WKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVILAGIP 76
            |:.|:.:.|.     |.||.|::|:::.|.:....|.||.......|..:|.|.|:||::..|||
Mouse   113 RMSRESSEGYPPRQLWASKVEYMLAIMSYLLMPSGVLRFASGWVHKGSCSFFIAYILMLLGIGIP 177

  Fly    77 LFYMEILIGQFSSTGCTGMFR-MTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCFFKKVP 140
            |.::|:.:||.:......|:: ::|...|.|.:.|:|......|.:|..|:.:..:.:.|:..||
Mouse   178 LLFLEMAVGQRAQQSSADMWKNLSPWFGGVGYSMVMVCFITNTYLNVFNSWILFYMSHIFYFVVP 242

  Fly   141 WEDC---SNSWNTD-DCVTASDMGKQNSSDVFKTSADEFFHLEVLRISTDISDLGGMVWEQLTAL 201
            |:.|   .||.|.| :|..|             ||...|::.:.|:.|..|.|.|...:....:|
Mouse   243 WDQCPLQRNSSNFDPECEQA-------------TSYTYFWYRKTLKASDRIEDGGQPSFSLGMSL 294

  Fly   202 IITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYPEWHRLLDLK 266
            .:::.:|...|:.||||:|||::..:..||.::...|||..::.||..|:|..|..:...:.||.
Mouse   295 FLSFCLICAFLVNGIKSIGKVLFVLLLVPYSIIVCFLIRTLSMDGAEYGLKHLLILKVASISDLT 359

  Fly   267 VWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLGFLS-- 329
            :|..|.:|:.|.||.|:|.||::||.....||...|:.|:....:.|.|:....:.|:|||.:
Mouse   360 IWCHAGIQVLFDIGLGFGPIVSLASHVPDFNNCMADAFLMALFKIITLLMTTPFLLSILGFWATT 424

  Fly   330 -----------------------------EKSGIPVESVATGGAGL------------------- 346
                                         :.||.|..:..:..:.|
Mouse   425 TTHHCCKKNQETLLRLVAQGILPPDAQPPDLSGNPTSNYNSWLSSLPPPLRSAVLSVVPECSVQK 489

  Fly   347 -----------AFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAIMSSILDEW-YWVR 399
                       .|:.:.|.|:|||....|.::||.:|..||:.|..:.:...:.::.|.: :..|
Mouse   490 QFLKIKDNPRFLFLIFTEVISLLPGSGFWIVLFFLLLLTLGLCSNLMFMLGNVLTLQDTFPFCRR 554

  Fly   400 SHKCKLTLISCLIFL-GLSSIMCTNGGMFILQLFD--WYSSAIAVIVICLVEIIMVAWIYGIKNF 461
            ..:..:..:|..:|| ||  |.....|::...|..  |.:..:.:|:||  |.:.|||.||...|
Mouse   555 QPRLLIVCVSMAMFLCGL--IFIQPSGIYYFSLLSECWVAVPVIIIIIC--ENLAVAWAYGADRF 615

  Fly   462 MLDVEFMLGKRPTLY---WRIVWQVVTPVIIIFILITSIVFI----------RTITYNNI--PYP 511
            :.|:..:|| ||...   |  :|..::|::::.:|.:..|::          .:.|...:  .:|
Mouse   616 LADMVALLG-RPIFSGCGW--LWCYISPMVVLGLLTSVFVYLVKGPLVYFAWDSSTSKEVVRVFP 677

  Fly   512 QWA-IIIGWASCFTSVMWIPLYIFYIM 537
            :|: |:|...:.|. :|.||.|..|.:
Mouse   678 EWSKILIAGLTVFV-LMPIPAYFVYCL 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:294310	154/605 (25%)
Slc6a16	NP_001311464.1	SLC5-6-like_sbd	125..694	CDD:294310	148/589 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920