Protein Alignment Ntl and ine

DIOPT Version :10

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_477012.1
• Gene: ine / 33659
• FlyBaseID: FBgn0011603
• Length: 943
• Species: Drosophila melanogaster
• Alignment Length: 578
• Identity: 215/578 - (37%)
• Similarity: 332/578 - (57%)
• Gaps: 31/578 - (5%)

  Fly     1 MANNQ-PPTTNATRKDKRIERDENRGQ-------WKSKSEFILSLLGYAIGIGNVWRFPYLCYRS 57
            |.|.| ||.......|..::..:...|       |.:|.:|:|:.:||::|:||||||||:||:|
  Fly   306 MVNPQTPPPLGVDDDDSYLDMSDETAQLKPRQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKS 370

  Fly    58 GGAAFLIPYLLMVILAGIPLFYMEILIGQFSSTGCTG-MFRMTPLLKGTGIAQVVVNAYCVCYYS 121
            ||..||:||.:::.:..|||.:||:.:||::..|..| :.::.||.||.|:|.|||:.....|||
  Fly   371 GGGVFLVPYCIILFICSIPLLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYS 435

  Fly   122 VIISYPIRMIFYCFFKKVPWEDCSNSWNTDDCVTASDMG-KQNSSDVFKTSADEFFHLEVLRIST 185
            |||.|.|...|..|..::||.||:|.|||.||......| ..::.|..:|.::|||..:||:||.
  Fly   436 VIIGYSIYYFFTSFKTEMPWIDCNNRWNTPDCWVPQRKGINASAPDTSRTPSEEFFENKVLQISG 500

  Fly   186 DISDLGGMVWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKG 250
            .:...|.|.||....||..|:::||...:.|||..||.|||..||::|:.||::|..||.||.:|
  Fly   501 GLEYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLDGAAEG 565

  Fly   251 IKFYLYPEWHRLLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSL 315
            ::|:..|:|..|.:..||.:||.|.|..:|..:|.:::.||::.:.||...|:|.:.::|:.|||
  Fly   566 LRFFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVNMITSL 630

  Fly   316 LAGFVVFSVLGFLSEKSGIPVESVATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSV 380
            |.|...||.||.|:.:....|..|...|.|:.||.||:|:|.:|..||||:||||||..||::|.
  Fly   631 LVGIFAFSTLGNLALEQNTNVRDVIGDGPGMIFVVYPQAMAKMPYAQLWAVMFFFMLLCLGLNSQ 695

  Fly   381 FVQLEAIMSSILDEW-YWVRSH----------KCKLTLISCLIFLGLSSIMCTNGGMFILQLFDW 434
            |..:|.:::||.|.: .|::.|          .|   :||||  .|:.:|:  .||::..||.|.
  Fly   696 FAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFVC---VISCL--FGMPNII--QGGIYYFQLMDH 753

  Fly   435 YSSAIAVIVICLVEIIMVAWIYGIKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVF 499
            |::::.::.:...::|.:||.||......:|:.|.||.|:.|.|..|.|:.|.::..|.:.|::.
  Fly   754 YAASVTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLIN 818

  Fly   500 IRTITYNN--IPYPQWAIIIGWASCFTSVMWIPLYIFYIMIRKRA-TLCDSLKKRLKP 554
            ....||:|  ..||.||..|||.....|::.||.|.....:|... |..:.::..|:|
  Fly   819 YHEPTYHNGRYTYPDWAYGIGWMFASFSLICIPGYAVINFLRSSGDTFWERIRNTLRP 876

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	208/552 (38%)
ine	NP_477012.1	SLC5-6-like_sbd	337..876	CDD:444915	207/545 (38%)