Protein Alignment Ntl and slc6a19b

DIOPT Version :10

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_956030.1
• Gene: slc6a19b / 326030
• ZFINID: ZDB-GENE-030131-4755
• Length: 651
• Species: Danio rerio
• Alignment Length: 574
• Identity: 187/574 - (32%)
• Similarity: 305/574 - (53%)
• Gaps: 82/574 - (14%)

  Fly    16 KRIERDE--NRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVILAGIPLF 78
            :|:|.:|  :|.:|.:|::::|:.:|:.:|:||||||||||...||.||:||:|::::..||||.
Zfish    23 ERLEVEEAGDRPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVFEGIPLL 87

  Fly    79 YMEILIGQFSSTGCTGMFR-MTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCFFKKVPWE 142
            ::|..|||....|..|::| :.|.:.|.|||.:.|:.....||:.||::.:...|..|...:||.
Zfish    88 HLEFAIGQRLRKGSVGVWRTINPYMLGVGIASMCVSFLVSLYYNTIIAWVMWYFFNSFQDPLPWS 152

  Fly   143 DCSNSWNTDDCVTASDMGKQNSSDVFKTSADEFFHLEVLRISTDISDLGGM-VWEQLTALIITWI 206
            .|..:.|....:  .:.||  ||.|     |.|::.|.|..|..|.|.||: || .:..||..|.
Zfish   153 QCPINENRTGPI--PECGK--SSPV-----DYFWYRETLNTSAAIDDTGGLQVW-MVLCLISAWA 207

  Fly   207 IIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYPEWHRLLDLKVWADA 271
            ::|.|.:|||::.||.||.|...|||:|.|.||||.||.|:..||||...|:.:.|.:...|.||
Zfish   208 VLYVCCIRGIETTGKAVYVTSTLPYLVLTIFLIRGLTLKGSVDGIKFLFTPDINELANPSTWLDA 272

  Fly   272 AVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLGF--------- 327
            ..|:|:.....:||:::.:|::|..||.:.|:|:|..||.|||:.|..|::|::||
Zfish   273 GAQVFYSFSLAFGGLISFSSYNSVHNNCEQDAVIISVINAFTSIYAATVIYSIIGFRATERFDDC 337

  Fly   328 ------------------------------LSEKSGIPVESVA-------------TGGAGLAFV 349
                                          |:..|...:.|::             ..|.||||:
Zfish   338 MNGNILTLLNTFDLPEGFINQSNYQDVFQSLNSTSPDIISSLSLKTCDLNNFLSEGVEGTGLAFI 402

  Fly   350 TYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAIMSSILDEWYWVRS-HKCKLTLISCLIF 413
            .:.|||..:|:..||:::||.|||.||:.|:|..:|.::..:.|...:.:| .|..::.::||:.
Zfish   403 VFTEAITKMPLSPLWSVLFFIMLFCLGLSSMFGNIEGVLVPLQDLGVFPKSWPKEIISGVTCLVC 467

  Fly   414 LGLSSIMCTNGGMFILQLFDWYSSAIAVIVICLVEIIMVAWIYGIKNFMLDVEFMLGKRPTLYWR 478
            ..:..|.....|.:.|.|||.::.:|.:::|...|:|.|.::|||..|..|:.||:|.:|.::|:
Zfish   468 CLVGLIFVQGSGNYWLALFDSFAGSIPLLIIAFSEMIGVVYVYGIDRFNEDLIFMIGHKPNIFWQ 532

  Fly   479 IVWQVVTPVII--IFILITSIVFIRTITYN-------------NIPYPQWAIII 517
            ..|:.::|:|:  ||:...|....:.|.|:             ..|||.|..:|
Zfish   533 ATWRFISPLIMLAIFVFYFSTTVTKEIFYSAWDPESENFPTLEKKPYPTWIYVI 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	184/564 (33%)
slc6a19b	NP_956030.1	SLC6sbd_B0AT1	33..613	CDD:212085	184/564 (33%)