DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ntl and CG10804

DIOPT Version :9

Sequence 1:	NP_609135.1	Gene:	Ntl / 34046	FlyBaseID:	FBgn0267326	Length:	590	Species:	Drosophila melanogaster
Sequence 2:	NP_001138150.1	Gene:	CG10804 / 31317	FlyBaseID:	FBgn0029663	Length:	726	Species:	Drosophila melanogaster

Alignment Length:	574	Identity:	195/574 - (33%)
Similarity:	312/574 - (54%)	Gaps:	67/574 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TTNATRKD--KRIERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMV 70
            |.:|.::|  :..:..|.|..|.||..|:|:.:|||:|:|||||||||..::||.|||:||.:|:
  Fly   100 TASADQQDIVEGEKEGEERESWDSKIMFLLATIGYAVGLGNVWRFPYLAQKNGGGAFLVPYFIML 164

  Fly    71 ILAGIPLFYMEILIGQFSSTGCTGMF-RMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYC 134
            .:.|||:||:|:.|||....|..|:: :::|.|.|.||:..||:.....||:.||::.:..:.:.
  Fly   165 CIQGIPIFYLELAIGQRLRKGAIGVWSQVSPYLGGIGISSAVVSYIVALYYNTIIAWCLIYLLHS 229

  Fly   135 FFKKVPWEDCS----NSWNTD---DCVTASDMGKQNSSDVFKTSADEFFHLEVLRISTDISDLGG 192
            |...:||.||.    .::..|   :||.:|             ....:::...|:.|..:.....
  Fly   230 FESPLPWADCPTRLYKNFTYDHEPECVASS-------------PTQFYWYRTTLQCSESVDMPEN 281

  Fly   193 MVWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYP 257
            ..:....|||::|.::|.|:::||.|.||:||.|..|||::|.|...||.||.||..|:.....|
  Fly   282 FNYHMAIALIVSWFLVYICMVQGITSSGKIVYMTAIFPYVVLIIFFFRGITLKGAADGVAHLFTP 346

  Fly   258 EWHRLLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVF 322
            .|..|||..||.:|..|:||.:|..:||::..:|::...||...|::|:...|..||:.||.|||
  Fly   347 RWETLLDPVVWLEAGTQIFFSLGLAFGGLIAFSSYNPANNNCYRDAILVSLTNCGTSMFAGVVVF 411

  Fly   323 SVLGF---------LSEKSG---------IPVESVAT------GGAGLAFVTYPEAIALLPVPQL 363
            ||:||         ..|::|         :||..:.|      .|.||||:.:.|||...|..||
  Fly   412 SVIGFKATATFDRCTEERNGLVAQNKTHNLPVCDLQTELANSASGTGLAFIIFTEAINQFPGAQL 476

  Fly   364 WALMFFFMLFLLGIDSVFVQLEAIMSSILDEWYWVRSHKCKLTLISCLIFLGLSSIMC-TNG-GM 426
            ||::||.|||.|||||.|..||.:::|::|...:  .:..|..::..|.|...:..|| .|| |.
  Fly   477 WAVLFFLMLFTLGIDSQFGTLEGVVTSLVDMKLF--PNLPKEYIVGALCFSCCTISMCFANGAGS 539

  Fly   427 FILQLFDWYSSAIAVIVICLVEIIMVAWIYGIKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIF 491
            :|.||.|.::....:::|.|.|.:.:::|||::.|..|:|.|.|.||..||...|:.::|..::.
  Fly   540 YIFQLMDSFAGNFPLLIIALFECLSISYIYGVRRFSDDIEMMTGSRPNFYWMFCWKYLSPCAMVT 604

  Fly   492 ILITSIVFIRTITYNN--------------IPYPQWAIIIGWASCFTSVMWIPL 531
            ||:.|  |.:.:|..:              :.:|.|.|::.:....:|::|||:
  Fly   605 ILLAS--FYQLLTEGSSYPAWIGSKGATEGMEWPHWCIVVAFFLILSSILWIPI 656

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:294310	191/556 (34%)
CG10804	NP_001138150.1	SLC6sbd-B0AT-like	120..661	CDD:271364	190/554 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910