Protein Alignment Ntl and Slc6a7

DIOPT Version :10

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_006525992.1
• Gene: Slc6a7 / 240332
• MGIID: 2147363
• Length: 684
• Species: Mus musculus
• Alignment Length: 562
• Identity: 222/562 - (39%)
• Similarity: 358/562 - (63%)
• Gaps: 13/562 - (2%)

  Fly    15 DKRIERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVILAGIPLFY 79
            |..::...:||.|..|.:|:||.:||.:|:||||||||..|.:||.|||:||.||:.:.|||||:
Mouse    75 DLDVDFAADRGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFF 139

  Fly    80 MEILIGQFSSTGCTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCFFKKVPWEDC 144
            :|:.:|||||.|...:::::||.||.|.|.:::......||::||:|.:..:|......:|||.|
Mouse   140 LELSLGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSNLPWEHC 204

  Fly   145 SNSWNTDDCVTASDMGKQNSSDVFK-------TSADEFFHLEVLRI--STDISDLGGMVWEQLTA 200
            .|.|||:.|:  ...|.::.:.|..       :.::|::...||.|  |..|...|.:.|.....
Mouse   205 GNWWNTELCL--EHRGPKSGNGVLPLNLSSTVSPSEEYWSRYVLHIQGSQGIGRPGEIRWNLCLC 267

  Fly   201 LIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYPEWHRLLDL 265
            |::.|:|::.|:::|:||.|||||||..||||:|.:||:||.|||||||||:|||.|::|.||..
Mouse   268 LLLAWVIVFLCILKGVKSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLTPQFHHLLSS 332

  Fly   266 KVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLGFLSE 330
            |||.:||:|:|:.:|.|:||::..||:::|..|...|:.::...|..||:||||.:|||||::|:
Mouse   333 KVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSILAGFAIFSVLGYMSQ 397

  Fly   331 KSGIPVESVATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAIMSSILDEW 395
            :.|:||:.||..|.|||||.||:|:.:||:...|:.:|||||..||:||.|..||.|::::.||:
Mouse   398 ELGVPVDQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQFAFLETIVTAVTDEF 462

  Fly   396 -YWVRSHKCKLTLISCLIFLGLSSIMCTNGGMFILQLFDWYSSAIAVIVICLVEIIMVAWIYGIK 459
             |::|..|...:.:.|:....:..|:.|:|||:.|.|.|.||::..::|:.:...:.|..:|||:
Mouse   463 PYYLRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDYSASFGLMVVVITTCLAVTRVYGIQ 527

  Fly   460 NFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFIRTITYNNIPYPQWAIIIGWASCFT 524
            .|..|:..|||.:|.||:|..|..::|..::.:|:.|||..:...|.:..:|.||.::|......
Mouse   528 RFCRDIHMMLGFKPGLYFRACWLFLSPATLLALLVYSIVKYQPSEYGSYRFPAWAELLGILMGLL 592

  Fly   525 SVMWIPLYIFYIMIRKRATLCDSLKKRLKP-LDWTPADPQDR 565
            |.:.||..:...::|:..:|.:.|::..:| :||.|:..::|
Mouse   593 SCLMIPAGMLVAVLREEGSLWERLQQASRPAMDWGPSLEENR 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	216/539 (40%)
Slc6a7	XP_006525992.1	SLC5-6-like_sbd	84..628	CDD:444915	219/545 (40%)