Protein Alignment Ntl and F56F4.3

DIOPT Version :10

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_491770.3
• Gene: F56F4.3 / 186398
• WormBaseID: WBGene00018980
• Length: 701
• Species: Caenorhabditis elegans
• Alignment Length: 641
• Identity: 130/641 - (20%)
• Similarity: 258/641 - (40%)
• Gaps: 106/641 - (16%)

  Fly     7 PTTNATRKDKRIERDE------NRGQWKSKSEFILSLLGYAIG-IGNVWRFPYLCYRSGGAAFLI 64
            ||.|......:||.:|      :|...:..:...||||...:. :.|...|....:..||..|.:
 Worm    78 PTGNPNLNPSKIEAEELEQEIGSRNISRPSTYRQLSLLLSCVTLLKNNMVFIECFFNHGGVYFFV 142

  Fly    65 PYLLMVILAGIPLFYMEILIGQFSSTGCTGMF-RMTPLLKGTGIAQVVVNAYCV-CYYSVIISYP 127
            ||.:::.:.|:|:...|:.:.||||....||| ||.|:|  .||..:::   |: ..|:|.|::.
 Worm   143 PYFIILFVLGVPMAIFELSLAQFSSIPMNGMFTRMAPML--GGIPWLIL---CLRIIYTVYIAFD 202

  Fly   128 IRMIFYCFFKKVP-------WEDCSN---------SWN--------TDDCVTASDMGKQNSSDVF 168
            .|.:.|.:...|.       |..|.:         :|:        ..:||....:.|......:
 Worm   203 PRFLLYAYKSFVTVITGNMNWIHCDDYKGVRCFDPTWSCKINEFRLNGECVKDVHIRKLAQQQDY 267

  Fly   169 KTSADEFFHLEVLRISTDI-----SDLGGM-VWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTV 227
            ....  :|.|...|:.:.|     .::.|: :.:.:.|.::..:|..|...:|.:....:..|.|
 Worm   268 GLLT--YFGLREYRLISIIPSQIYKEINGLDIMDNILAALVFLLIAGFITYKGHRFFASLAGFFV 330

  Fly   228 PFPYLLLFILLIRGATLPGAWKGIKFYLYP-----EWHRLLDLKVWADAAVQMFFGIGPGWGGIV 287
            ..|.|.:...:|......|:.|  |.:...     :..::.:|..|.:||......:....|.::
 Worm   331 FLPILGMIPAVILVYYDVGSRK--KHFFNQILKNNDITKIFELSAWLNAARVTVKTVYIADGTLM 393

  Fly   288 NMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLGFLSEKSGIP-VESVATGGAGLAFVTY 351
            .:.|.:.||:|...|:||:.:......||..|.:..:| :::.....| .::|...|..:.|...
 Worm   394 ALGSRADFRHNFIKDAVLLAASGATYRLLLCFGILPIL-YVANDILYPFAKTVYARGDLVQFHAI 457

  Fly   352 PEAIALLP---VPQLWALMFFFMLFLL--GIDSVFVQLEAI--------MSSILDEWYWVRSHKC 403
            ....:.||   :|.:...:.||:..:|  .|:..||..:.|        :..:.....:::....
 Worm   458 ELFFSALPSYAIPGISPTVTFFVYAMLYGTINFAFVAYQVITFEMLINALHHLFPRLLYLKQKSV 522

  Fly   404 KLTLI----SCLIFLGLSSI---MCTNGGMFILQLFDWYSSAIAVIVICLVEIIMVAWIYGIKNF 461
            ::.:|    :.|:||.:.|:   ....|....|.:.|:....::..|  .:::|.|:.:||.|..
 Worm   523 RICIIMATVTLLLFLYILSLPYKQLAVGYQKELAIDDYVVGLVSTTV--FIQLISVSIVYGYKRL 585

  Fly   462 MLDVEFMLGKRPTLY---------WRIVWQVVTPVIIIFILITSIVFIRTITYNNIPYPQWAIII 517
            :::...||...|..|         ..::|....|:..: :.|.||:..:...|:      |.:::
 Worm   586 LINFLTMLKHHPVTYKLVEKCRVFLYVMWAFFLPISCL-VSICSIIVKKYQIYH------WPLVL 643

  Fly   518 GWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLKPLD----WTPADPQDRAEYE 569
                 :.::..:||    |.:.::.|:....|:.:..|.    |.||:.....|.|
 Worm   644 -----YAAISALPL----IYLARKLTMYIMRKEFVSGLSQTHRWQPANEGHAREVE 690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	118/597 (20%)
F56F4.3	NP_491770.3	SLC5-6-like_sbd	73..620	CDD:444915	113/553 (20%)