Protein Alignment Ntl and snf-12

DIOPT Version :10

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_509527.1
• Gene: snf-12 / 181143
• WormBaseID: WBGene00004911
• Length: 1022
• Species: Caenorhabditis elegans
• Alignment Length: 614
• Identity: 183/614 - (29%)
• Similarity: 317/614 - (51%)
• Gaps: 69/614 - (11%)

  Fly    19 ERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVILAGIPLFYMEIL 83
            ::::.|..|:::.:|.||.||:.:|:|:..|||...|:.||..|.||||..:|..|:||.::.:.
 Worm   152 KQNDRRELWRTQKDFFLSCLGFMVGVGHTMRFPAKVYQHGGGVFFIPYLFSLIFFGLPLVFLHLS 216

  Fly    84 IGQFSSTGCTGMF-RMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCFFK---------K 138
            :||::.......| |:.|:..|.|.|.||:......||::|:::.|    :.||:         :
 Worm   217 LGQYTGQAANTAFQRLMPIGSGVGWALVVIAIPVAVYYNIIVAWAI----HYFFQSAKGLLLGDE 277

  Fly   139 VPWEDCSNSWNTDD-CVTASDMGKQNSSDVFKTSADEFFHLEVLRIST--DISDLGGMVWEQLTA 200
            :|||.|.:.|..|: |....::....:|....|:.:.|||.|||.:||  |.: ||.:....:.:
 Worm   278 LPWETCRDEWQLDNRCCNLHNLHSCFNSTNSITAPEAFFHSEVLSLSTFGDFA-LGPLQSHLVLS 341

  Fly   201 LIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYPEWHRLLDL 265
            |...|::::|.:.:|:.|:.:.:..|...|||||.|||:||.:||||.||:.|....:..:|...
 Worm   342 LAAAWLLVFFGVFKGLGSIAQTMNVTATVPYLLLSILLLRGISLPGANKGLTFLFTVDSTKLWKW 406

  Fly   266 KVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLGFLSE 330
            ::|..||.|:|:.:|...|.:::||:||.:|||...||||:|.::..||.|:|.|:||.:||::.
 Worm   407 QIWKSAAEQVFYELGIDAGPLISMAAFSRYRNNIYRDSVLLVIMDALTSCLSGMVIFSFVGFIAS 471

  Fly   331 KSGIPVESVAT-GGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAIMSSILDE 394
            :|...|..|.. ....|:|..||...:.:....|||.:||.||.|..||:.|..||.|.|:.::
 Worm   472 ESNSNVNDVLKHDPLYLSFTVYPGVTSFMYWGGLWATLFFGMLVLAAIDAEFAWLEMIASAFMN- 535

  Fly   395 WYWVRSHKC---KLTLISCL--IFLGLSSIMCTNGGMFILQLFD-----WYSSAIAVIVICLVEI 449
             ::...:|.   :|....||  .||||.  :|..||:|:....:     |.|.::|     |:.:
 Worm   536 -HFSMKNKAVENRLLAFLCLAGFFLGLP--LCAQGGIFVFHAIENLNANWNSFSLA-----LLSV 592

  Fly   450 IMVAWIYGIKNFMLDVEFML-------GKRPTLYWRIVW-------------QVVTPVIIIFILI 494
            .:|.::|||.|::.|:..||       .|...|..::::             ..:.|||:..:|:
 Worm   593 AIVCYVYGIDNYLTDISAMLRVPRIQISKATRLKEKLIYFFGPGGIYIKFSLCFICPVILTVLLV 657

  Fly   495 TSIVFIRTITYNNIPYPQWAIIIGWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLKPLDWTP 559
            .|::..:.|::...|.|....|:.|......::.:|| :.::.||:.......||......:|..
 Worm   658 ASVLGYQRISFAGRPIPIDYEIVAWIVMIGPLLVVPL-VAFMQIRQIRNEGKLLKSLFDTSEWRE 721

  Fly   560 A-----DPQD-----RAEYEAFRRQRRMP 578
            :     :|:|     ..::|:...:||.|
 Worm   722 SQDDSLEPKDLYMRQSGKFESPPNRRRTP 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	176/573 (31%)
snf-12	NP_509527.1	SLC6sbd	158..660	CDD:271359	163/515 (32%)