Protein Alignment Ntl and DAT

DIOPT Version :10

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_061499264.1
• Gene: DAT / 1269812
• VectorBaseID: AGAMI1_006978
• Length: 678
• Species: Anopheles gambiae
• Alignment Length: 580
• Identity: 234/580 - (40%)
• Similarity: 351/580 - (60%)
• Gaps: 43/580 - (7%)

  Fly    18 IERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVILAGIPLFYMEI 82
            ::..|.|..|..|.:|:||::|:|:.:.||||||||||::||.||||||.:|:::.||||||||:
Mosquito    89 LDDGEERETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLIPYGIMLVVGGIPLFYMEL 153

  Fly    83 LIGQFSSTG---CTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCFFKKVPWEDC 144
            .:|||:..|   |.|  |:.||.||.|.|.|::..|...||:|||::.:|..|..|...:||..|
Mosquito   154 ALGQFNRKGAITCWG--RLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTDSLPWTHC 216

  Fly   145 SNSWNTDDCVTASDMGKQNSSDV------------------------FKTSADEFFHLEVLRI-- 183
            ||:|||.:|   ...|..||:..                        |.::|.|:|:..:|.:
Mosquito   217 SNAWNTVEC---KPFGYINSTAATVVNRTGVLAANVTGTVSTINDTKFASAASEYFNRYILELDK 278

  Fly   184 STDISDLGGMVWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAW 248
            |..|.|||.:.|:....|:..::|.||.|.:||.:.||||:||..|||.:|.|||:||.||||:.
Mosquito   279 SEGIHDLGAIKWDMALCLLAVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLVRGITLPGSA 343

  Fly   249 KGIKFYLYPEWHRLLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFT 313
            :||.:||.|.:..:.:.:||.|||.|:||.:|||:|.::..||::.:.||...|::|...||..|
Mosquito   344 EGILYYLRPNFDVIYNAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSLINSAT 408

  Fly   314 SLLAGFVVFSVLGFLSEKSGIPVESVATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGID 378
            |.:||||:|||||:::..||..::.|||.|.||.||.||.|||.:|....|||:||.||..||:|
Mosquito   409 SFIAGFVIFSVLGYMAHASGQSIQDVATEGPGLVFVVYPAAIATMPGSIFWALIFFMMLLTLGLD 473

  Fly   379 SVFVQLEAIMSSILDEWYWV-RSHKCKLTLISCLIF-LGLSSIMCTNGGMFILQLFDWYSSAIAV 441
            |.|...|||::::.||:..: |:.:..:.::..|.| :||:|  ||.||.:..||.|.|::..::
Mosquito   474 SSFGGSEAIITALSDEFPKIGRNREIFVAVLFSLYFVVGLAS--CTQGGFYFFQLLDRYAAGYSI 536

  Fly   442 IVICLVEIIMVAWIYGIKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFIRTITYN 506
            ::....|.|.|:||||.:.|..|::.|:|..|.:|||:.|:.|.|:.::||:|..::....::|.
Mosquito   537 LIAVFFEAIAVSWIYGTERFCNDIKDMIGFAPGIYWRVCWKFVAPLFLLFIIIYGLIGHEPLSYE 601

  Fly   507 NIPYPQWAIIIGWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLKPLDWTPADPQDRA 566
            :..||.||.::||....:|::.|||...|.:|    ....||::|.|.|. ||...|..|
Mosquito   602 DYVYPSWANVLGWCIAGSSMIMIPLMASYKLI----VTPGSLRQRFKILT-TPWRDQQMA 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	227/560 (41%)
DAT	XP_061499264.1	None