Protein Alignment Ntl and Slc6a8

DIOPT Version :10

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_598748.1
• Gene: Slc6a8 / 102857
• MGIID: 2147834
• Length: 640
• Species: Mus musculus
• Alignment Length: 560
• Identity: 215/560 - (38%)
• Similarity: 334/560 - (59%)
• Gaps: 33/560 - (5%)

  Fly    24 RGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVILAGIPLFYMEILIGQFS 88
            |..|..:.:||:|.:|:|:|:|||||||||||::||..|||||:|:.::.|||:|::||.:|||.
Mouse    52 RETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFM 116

  Fly    89 STGCTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCFFKKVPWEDCSNSWNTDDC 153
            ..|...::.:.||.||.|.|.:|:..||..||.:::::....:...|...:||..|.::|||.||
Mouse   117 KAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDC 181

  Fly   154 V----------------TASDMGKQNSSDVFKTSADEFFHLEVLRISTDISDLGGMVWEQLTALI 202
            |                |...:..:.|..:      ||:..:|||:||.:...|.:.||....|:
Mouse   182 VEIFRHEDCANASLANLTCDQLADRRSPVI------EFWENKVLRLSTGLEVPGALNWEVTLCLL 240

  Fly   203 ITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYPEWHRLLDLKV 267
            ..|:::|||:.:|:||.||:||||..|||::|.:||:||..||||..||.:||.|:|.:|...:|
Mouse   241 ACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQV 305

  Fly   268 WADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLGFLSEKS 332
            |.||..|:||....|.|.:..:.|::.|.||...|::::..||..||..|||||||:|||::.:.
Mouse   306 WIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMATEQ 370

  Fly   333 GIPVESVATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAIMSSILD---- 393
            |:.:..||..|.||||:.||.|:.|:||..|||.:|||||.|||:||.||.:|..::.:||
Mouse   371 GVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPA 435

  Fly   394 EWYWVRSHKCKLTLISCLIF-LGLSSIMCTN---GGMFILQLFDWYS-SAIAVIVICLVEIIMVA 453
            .:|:....:..:.|...|.| :.||.:...:   |||::.||||:|| |...::.....|.::||
Mouse   436 SYYFRFQREISVALCCALCFVIDLSMVTDVSGGKGGMYVFQLFDYYSASGTTLLWQAFWECVVVA 500

  Fly   454 WIYGIKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFIRTITYNN-IPYPQWAIII 517
            |:||...||.|:..|:|.||..:.:..|...||::.:.|.|.:||:...:.||| ..||.|...:
Mouse   501 WVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNIVYYEPLVYNNTYVYPWWGEAM 565

  Fly   518 GWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLKPLDW 557
            |||...:|::.:||::...::|.:.|:.:..:...:|: |
Mouse   566 GWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQPI-W 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	213/555 (38%)
Slc6a8	NP_598748.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27
		SLC6sbd_CT1	52..626	CDD:271397	215/560 (38%)