Protein Alignment Ntl and slc6a4l

DIOPT Version :10

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_012825214.2
• Gene: slc6a4l / 100496361
• XenbaseID: XB-GENE-981144
• Length: 590
• Species: Xenopus tropicalis
• Alignment Length: 571
• Identity: 219/571 - (38%)
• Similarity: 357/571 - (62%)
• Gaps: 36/571 - (6%)

  Fly     3 NNQPPTTNATRKDKRIERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYL 67
            ||..|....|:.|       :|.:|..|.:|:||::|:|:.:||||||||:||::||.||||||.
 Frog    23 NNAMPLPLITQAD-------SRDKWSKKMDFLLSVIGFAVDLGNVWRFPYICYQNGGGAFLIPYT 80

  Fly    68 LMVILAGIPLFYMEILIGQFSSTGCTGMF-RMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMI 131
            :|.|..|:||||||:.:|||...|...:: |:.|:.||.|.|..::..|...||:.||::.:...
 Frog    81 IMAIFGGVPLFYMELALGQFHRMGAIPIWKRICPIFKGIGFAICIIALYVSFYYNTIIAWALFYF 145

  Fly   132 FYCFFKKVPWEDCSNSWNTDDCVTASDMGKQNS--SDVFKTSADEFFHLEVLRI--STDISDLGG 192
            :..|.:.:||.:|.|.|||.:|  .:..|:.|.  ::..|:.|:||:..:||.|  :..:.::||
 Frog   146 YSSFTETLPWTNCDNPWNTPNC--TNYFGRSNITWNNYSKSPAEEFYTRKVLGIHEAEGLDNVGG 208

  Fly   193 MVWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYP 257
            :.|:.:..|.|.:.|:||.|.:|:|:.||||:.|...||::|.|||||||||||||:||.|||.|
 Frog   209 LRWQLILCLFIIFTIVYFSLWKGVKTSGKVVWVTATLPYVVLLILLIRGATLPGAWRGILFYLRP 273

  Fly   258 EWHRLLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVF 322
            :|.:|:|..||.|||.|:||.:|||:|.::.::|::.|.||...|:::..::|..||.::|||:|
 Frog   274 KWEKLMDTAVWVDAAAQIFFSLGPGFGVLLALSSYNPFHNNCYRDALITSTVNCLTSFVSGFVIF 338

  Fly   323 SVLGFLSEKSGIPVESVATG-GAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEA 386
            :|||:::|..|:.||.||.. |..|.|:|||||||.:.....:|::||.|:..||:||.|..|||
 Frog   339 TVLGYMAEMRGVEVEDVAKDKGPSLLFITYPEAIANMVGSTFFAIIFFLMMITLGLDSTFGGLEA 403

  Fly   387 IMSSILDEWYWVRSHKCKLTLISCLI--FLGLSSIMCTNGGMFILQLFDWYSSAIAVIVICLVEI 449
            |:::::||:..:.|.:.:|.::..:|  |.|..|.: |.||.::::|.:.:.:...:|.:..:|.
 Frog   404 IITAVMDEYPHILSKRRELFVLGLVIVCFTGSLSTL-TYGGAYVVKLLEQFGAGCPIIAVVFLEA 467

  Fly   450 IMVAWIYGIKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFIRTITYNNIPYPQWA 514
            |.|:|.|||:.|..||:.|||..|.::|||.|..::|..:.||:::|::....:...:..||:|.
 Frog   468 IAVSWFYGIQRFSNDVKSMLGFVPGIFWRICWVAISPAFLAFIIVSSLMDQPPLILFDYQYPKWT 532

  Fly   515 IIIGWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLKPLDWTPADPQDR 565
            :.:|:....:|.:|||:|:.|.::                  |||...::|
 Frog   533 VSVGFLIGASSFIWIPVYMVYKLV------------------WTPGSLKER 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	210/537 (39%)
slc6a4l	XP_012825214.2	SLC5-6-like_sbd	37..573	CDD:444915	214/550 (39%)