Protein Alignment Ntl and slc6a5

DIOPT Version :9

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_031756248.1
• Gene: slc6a5 / 100495275
• XenbaseID: XB-GENE-993852
• Length: 789
• Species: Xenopus tropicalis
• Alignment Length: 598
• Identity: 237/598 - (39%)
• Similarity: 361/598 - (60%)
• Gaps: 41/598 - (6%)

  Fly     6 PPTTNATRKDKRIERDEN--RGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLL 68
            |.|.|...     |.|||  ||.|.||.:||||::|||:|:|||||||||.:::||.|||||||.
 Frog   168 PGTLNGDE-----EGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFKNGGGAFLIPYLT 227

  Fly    69 MVILAGIPLFYMEILIGQFSSTGCTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFY 133
            |:.|||:|:||||:.:|||:|.|...:::..|.|:|.|||.::::.....||::|:.|.|..:|.
 Frog   228 MLALAGLPIFYMEVALGQFASQGPISVWKAIPALQGCGIAMLIISVLIAIYYNIIMCYTIFYLFA 292

  Fly   134 CFFKKVPWEDCSNSWNTDDC-------VTASDMGKQ-------------------------NSSD 166
            .....:||..|:|.|||.||       :.:..:|.|                         :::.
 Frog   293 SLVSVLPWASCTNPWNTPDCKDKDRLMLDSCIIGSQPNIHIKNSTFCMTAYPNLTLVNFTSHANK 357

  Fly   167 VFKTSADEFFHLEVLRISTDISDLGGMVWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPY 231
            .|.:.::|:|...:|:||..|...|.:.|.....|.:.|.|:|..|.:||||.|||||||..|||
 Frog   358 SFVSGSEEYFKYNMLKISAGIEYPGEIRWPLAICLFLAWTIVYASLAKGIKSSGKVVYFTATFPY 422

  Fly   232 LLLFILLIRGATLPGAWKGIKFYLYPEWHRLLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFR 296
            ::|.||||||.|||||..||.:::.|:|.:|:|..||.|||.|:||.:...|||::.::|::.|.
 Frog   423 VVLVILLIRGVTLPGAGDGIWWFIMPKWEKLMDAMVWKDAATQIFFSLSAAWGGLITLSSYNKFH 487

  Fly   297 NNAKCDSVLIVSINVFTSLLAGFVVFSVLGFLSEKSGIPVESVATGGAGLAFVTYPEAIALLPVP 361
            ||...|::::...|..||:.||||:|||:||::....:.:|.||..|.|:|||.||||:..||:.
 Frog   488 NNVYRDTLIVTCTNSATSIFAGFVIFSVIGFMAHILNVDIEKVADQGPGIAFVVYPEALTRLPLS 552

  Fly   362 QLWALMFFFMLFLLGIDSVFVQLEAIMSSILDEW-YWVRSHKCKLTLISCLIFLGLSSIMCTNGG 425
            ..||::||.||..||:|::|..:|.|::|:.||: ..:|.||...|||.|:.|..:...|.|.||
 Frog   553 PFWAIIFFLMLLTLGLDTMFATIETIVTSVSDEFPKLLRPHKPLFTLICCVAFFIMGFPMITQGG 617

  Fly   426 MFILQLFDWYSSAIAVIVICLVEIIMVAWIYGIKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIII 490
            :::|||.|.|:::.::::|.:.|::.::::||::.|..|:|.|:|.:|:.:|::.|..|||.|:.
 Frog   618 IYMLQLVDNYAASYSLVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPSRFWKVCWAFVTPTILT 682

  Fly   491 FILITSIVFIRTITYNNIPYPQWAIIIGWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLKPL 555
            |||..|......:||.:..||.|::::||.....||:|||:.....|.....|..:.||....|.
 Frog   683 FILCFSFYQWEPMTYGSYHYPTWSMVMGWLMLACSVIWIPVMFVIKMYLAPGTFIERLKLVCSPQ 747

  Fly   556 -DWTPADPQDRAE 567
             ||.|...:.|.|
 Frog   748 PDWGPFLAKHRGE 760

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:294310	224/562 (40%)
slc6a5	XP_031756248.1	SLC6sbd_GlyT2	183..779	CDD:271389	230/578 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110