Protein Alignment Ntl and slc6a9

DIOPT Version :10

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_004914027.1
• Gene: slc6a9 / 100492204
• XenbaseID: XB-GENE-948182
• Length: 638
• Species: Xenopus tropicalis
• Alignment Length: 579
• Identity: 247/579 - (42%)
• Similarity: 363/579 - (62%)
• Gaps: 40/579 - (6%)

  Fly    11 ATRKDKRIERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVILAGI 75
            ||:||:    :..||.|.::.||:|:.:|||:|:||||||||||||:||.||:.||.:|::..||
 Frog    18 ATKKDE----NPKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLVFCGI 78

  Fly    76 PLFYMEILIGQFSSTGCTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCFF---- 136
            |||:||:..|||:|.||.|::|::|:.||.|...:||:.|...||:|:|.    :.||.||
 Frog    79 PLFFMELSFGQFASQGCLGVWRVSPIFKGVGYGMMVVSTYIGIYYNVVIC----IAFYYFFASMN 139

  Fly   137 KKVPWEDCSNSWNTDDCVTASDMGKQNSSDVFKTS---------------------ADEFFHLEV 180
            :.:||..|:|.|||::|   :.:...|||..|..|                     ::|::...|
 Frog   140 RILPWTYCNNLWNTENC---AGVLSPNSSATFNISSQHSLLNLTMGLNQTLKRTSPSEEYWRRHV 201

  Fly   181 LRISTDISDLGGMVWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLP 245
            |.||.||.|.|.:....|..|.::|::::.||:||:||.|||||||..|||::|.||.|||.||.
 Frog   202 LNISGDIGDFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFIRGITLD 266

  Fly   246 GAWKGIKFYLYPEWHRLLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSIN 310
            ||..||.:||.|:|.::|..|||.|||.|:|:.:|..|||::.|||::.|.||...||::|...|
 Frog   267 GAINGILYYLTPQWDKILHAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSIIISITN 331

  Fly   311 VFTSLLAGFVVFSVLGFLSEKSGIPVESVATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLL 375
            ..||:.||||:||:|||::...|:.|..||..|.|||||.||||:.|||:..||:::|||||.||
 Frog   332 CATSVYAGFVIFSILGFMATHLGVDVSEVADHGPGLAFVAYPEALTLLPISPLWSILFFFMLILL 396

  Fly   376 GIDSVFVQLEAIMSSILDE--WYWVRSHKCKLTLISCLIFLGLSSIMCTNGGMFILQLFDWYSSA 438
            |:.:.|..||.::::|:||  ..|:...|..:||...:|...|...:.|..|::.|.|.|.|:::
 Frog   397 GLGTQFCLLETLVTAIVDEIGSDWIIRWKTLVTLGVAIIGFLLGIPLTTQAGIYWLLLMDNYAAS 461

  Fly   439 IAVIVICLVEIIMVAWIYGIKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFIRTI 503
            .::::|..:..|.|.:|||.:|:..|:|.|||..|.|:::..|:..:|.||.||||.:::..|.|
 Frog   462 FSLVIISCIMCIAVMYIYGHRNYFKDIEMMLGFPPPLFFQFCWRFFSPAIIFFILIFTVIQYRPI 526

  Fly   504 TYNNIPYPQWAIIIGWASCFTSVMWIPLY-IFYIMIRKRATLCDSLKKRLKP-LDWTPA 560
            .||:..||.||:.||:....:||:.|||| :|.:...:..|....||..:|| .||.||
 Frog   527 KYNDYVYPDWALTIGFLMALSSVICIPLYAVFRVWRSEGHTFLQRLKNAVKPSKDWGPA 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	237/557 (43%)
slc6a9	XP_004914027.1	SLC6sbd_GlyT1	11..595	CDD:212067	247/579 (43%)