Protein Alignment Ntl and slc6a8

DIOPT Version :9

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_002935539.1
• Gene: slc6a8 / 100489909
• XenbaseID: XB-GENE-986840
• Length: 644
• Species: Xenopus tropicalis
• Alignment Length: 586
• Identity: 231/586 - (39%)
• Similarity: 352/586 - (60%)
• Gaps: 41/586 - (6%)

  Fly     6 PPTTNATRKDKRIERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMV 70
            ||..    |:...|||    .|.|:.:||:|.:|:|:|:|||||||||||::||..|||||:|:.
 Frog    48 PPNC----KEGIPERD----TWTSQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYILIA 104

  Fly    71 ILAGIPLFYMEILIGQFSSTGCTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCF 135
            ||.|||:|::||.:|||...|...::.:.||.:|.|.|.||:..:|..||.:|:::.:..:...|
 Frog   105 ILGGIPIFFLEIALGQFMKAGSIAVWNIAPLFQGIGFASVVIVFFCNTYYILILTWGVYYLVKSF 169

  Fly   136 FKKVPWEDCSNSWNTDDCV-----------TA-SDMGKQNSSDVFKTSAD------EFFHLEVLR 182
            ...:||..|:|:||:.|||           || |..|....:::    ||      ||:..:|||
 Frog   170 SAVLPWSHCNNTWNSPDCVDIFRQEDCTNGTANSTFGNLTCNEL----ADKVSPITEFWEKKVLR 230

  Fly   183 ISTDISDLGGMVWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGA 247
            :|:.:.|:|.:.||.|..||..|:::|||:.:|:||.||:||||..|||::|.|||:|||.||||
 Frog   231 LSSGLDDIGSINWELLLCLIGCWLLVYFCVWKGVKSTGKIVYFTATFPYVVLLILLVRGAMLPGA 295

  Fly   248 WKGIKFYLYPEWHRLLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVF 312
            .:||.:||.|:|.:|...:||.||..|:||....|.|.:..:.|::.|.|:...|:.::..||..
 Frog   296 TEGIIYYLKPDWSKLGTAQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNDCYKDAFILAVINSG 360

  Fly   313 TSLLAGFVVFSVLGFLSEKSGIPVESVATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGI 377
            ||..|||||||:|||::.:.|:.:..||..|.||||:.||.|::|:||..||:.:|||||.|||:
 Frog   361 TSFFAGFVVFSILGFMANEQGVDISKVAESGPGLAFIAYPRAVSLMPVAPLWSALFFFMLLLLGL 425

  Fly   378 DSVFVQLEAIMSSILD---EWYWVRSHKCKLTLISCLIFLGLSSIMCTNGGMFILQLFDWYS-SA 438
            ||.||.:|.::::|||   ..|:.|..:.....|.|.|...:...|.|.|||::.||||:|| |.
 Frog   426 DSQFVGVEGLITAILDLLPARYYFRFQREIAVAICCAIMFLIDLSMLTEGGMYVFQLFDYYSASG 490

  Fly   439 IAVIVICLVEIIMVAWIYGIKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFIRTI 503
            :.::.....:.::|||:||...||.|:..|:|.||..:.:..|..|||.:.:.|.:.:::..:.:
 Frog   491 MTLLWQTFWQCVVVAWVYGADRFMDDIARMIGYRPFPWMKWCWSFVTPFVCMAIFLFNLINYKPL 555

  Fly   504 TYNN-IPYPQWAIIIGWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLKP------LDWTPAD 561
            |||| ..||.|...|||....:|::.:|:...|.:...:.:|.:..:...||      |::...|
 Frog   556 TYNNSYTYPWWGEAIGWGFALSSMLCVPVTFLYKITCAKGSLRERWQHLTKPIWGAHHLEYMAPD 620

  Fly   562 P 562
            |
 Frog   621 P 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:294310	220/552 (40%)
slc6a8	XP_002935539.1	SLC5-6-like_sbd	58..644	CDD:382020	227/572 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820