Protein Alignment Ntl and slc6a3

DIOPT Version :9

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_002933174.1
• Gene: slc6a3 / 100488824
• XenbaseID: XB-GENE-982873
• Length: 621
• Species: Xenopus tropicalis
• Alignment Length: 556
• Identity: 219/556 - (39%)
• Similarity: 354/556 - (63%)
• Gaps: 17/556 - (3%)

  Fly     8 TTNATRKDKRIERDE-NRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVI 71
            |.:|.....:|..:. .|..|..|.:|:||::|:|:.:.||||||||||::||.|||:||:..::
 Frog    43 TNSALVSPSQINTENGERETWSKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYIFFMV 107

  Fly    72 LAGIPLFYMEILIGQFSSTGCTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCFF 136
            :||:||||||:.:|||:..|..|::::.|:.||.|...::::.|...:|:|||::.::.:|..|.
 Frog   108 IAGMPLFYMELALGQFNREGAAGVWKICPIFKGVGYTVILISLYVGFFYNVIIAWALQYLFSSFT 172

  Fly   137 KKVPWEDCSNSWNTDDCVTA-----SDMGKQNSSDVFK-TSADEFFHLEVLRI--STDISDLGGM 193
            .::||..|:||||:.:|...     ||......:|.:| |.|.|:|...||.:  |..|.|||..
 Frog   173 SELPWIHCNNSWNSPNCSETKYSNFSDYSLFGLNDTYKVTPAAEYFERGVLHLHESQGIHDLGSP 237

  Fly   194 VWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYPE 258
            .|:..:.||:..:.:||.|.:|:|:.||||:.|...||::|..||:||.|||||..|||.||..:
 Frog   238 RWKLTSCLIVVIVFLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIKAYLSVD 302

  Fly   259 WHRLLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFS 323
            :.||.:..||.|||.|:.|.:|.|:|.::..:|::.|.||...|:::..|:|..||..:|||:||
 Frog   303 FLRLCEASVWIDAATQICFSLGVGFGVLIAFSSYNKFTNNCYRDAIITTSVNSLTSFFSGFVIFS 367

  Fly   324 VLGFLSEKSGIPVESVATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAIM 388
            .||::::|..:|:..||..|.||.|:.||||||.||:..:|:::||.||..|||||....:|:::
 Frog   368 FLGYMAQKHNVPIGDVAKDGPGLIFIIYPEAIATLPLSSVWSVIFFIMLLTLGIDSAMGGMESVI 432

  Fly   389 SSILDEWYWVRSHKCKLTL--ISCLIFLGLSSIMCTNGGMFILQLFDWYSSAIAVIVICLVEIIM 451
            :.::||:.::|.|:...||  :.|..|..||.:  ||||:::..|.|.:::..:::...|:|.|.
 Frog   433 TGLIDEFKFLRRHRELFTLFIVLCTFFTSLSCV--TNGGIYVFTLLDHFAAGTSILFGVLIEAIG 495

  Fly   452 VAWIYGIKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFIRTITYNNIPYPQWAII 516
            :||.||:..|..|:|.|:||||.||||:.|:.|:|..::|:::.|||..|:..|.|..:|:||.:
 Frog   496 IAWFYGVGRFSDDIEEMIGKRPGLYWRLCWKFVSPCFLLFVVVVSIVTYRSPKYGNYTFPEWANV 560

  Fly   517 IGWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRL 552
            |||....:|:..:|||..|    |.::|..|.::::
 Frog   561 IGWLVAISSMAMVPLYAIY----KFSSLHGSFREKI 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:294310	216/539 (40%)
slc6a3	XP_002933174.1	SLC6sbd_DAT1	60..615	CDD:212083	216/539 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010