Protein Alignment Ntl and slc6a7

DIOPT Version :10

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_002940131.3
• Gene: slc6a7 / 100487063
• XenbaseID: XB-GENE-479449
• Length: 634
• Species: Xenopus tropicalis
• Alignment Length: 581
• Identity: 237/581 - (40%)
• Similarity: 372/581 - (64%)
• Gaps: 24/581 - (4%)

  Fly     5 QPPTTN-----ATRKDKR--IERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAF 62
            ||.|.:     :.|.|..  ||..|:||.|..|.:|:||.:||.:|:||||||||..|.:||.||
 Frog    11 QPVTPDLLMSPSDRDDTELDIEYPEDRGNWSGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAF 75

  Fly    63 LIPYLLMVILAGIPLFYMEILIGQFSSTGCTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYP 127
            ||||.:|:.:.|||||:||:.:|||||.|...:::::||.||.|:..:::.|....||::||:|.
 Frog    76 LIPYFIMLAICGIPLFFMELSLGQFSSLGPLAVWKISPLFKGVGMGMLLIVALVAIYYNMIIAYV 140

  Fly   128 IRMIFYCFFKKVPWEDCSNSWNTDDCVTASDMGKQNSSDVFKTS-----ADEFFHLEVLRI--ST 185
            :..:|......:|||.|.|.||||.|:....:...||:.:...|     ::|::...||.|  |:
 Frog   141 LFYLFASLTSSLPWEHCGNWWNTDLCLDHHVIRASNSALLVNISNTVSPSEEYWSRYVLHIQGSS 205

  Fly   186 DISDLGGMVWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKG 250
            .|.|.|.:.|:....|:::|.|:|.|:::|:||.|||||||..|||::|.:|||||.||.|||.|
 Frog   206 GIGDPGQLRWKLCLCLLLSWTIVYLCILKGVKSSGKVVYFTATFPYIILVMLLIRGVTLEGAWIG 270

  Fly   251 IKFYLYPEWHRLLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSL 315
            |||||.|::..||..|||.:||:|:|:.:|.|:||::..||:::|..|...|:.::...|.|||:
 Frog   271 IKFYLTPQFEHLLTSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAFTSI 335

  Fly   316 LAGFVVFSVLGFLSEKSGIPVESVATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSV 380
            ||||.:|||||::|::.|:||:.||..|.|||||.||:|:.:||:...|:.:|||||..||:||.
 Frog   336 LAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLGLDSQ 400

  Fly   381 FVQLEAIMSSILDEW-YWVRSHKCKLTLISCLIFLGLSSIMCTNGGMFILQLFDWYSSAIAVIVI 444
            |..:|.|:::|.||: |::|..|...:.|.|:....|..|:.|:|||:.|.|.|.||:...::||
 Frog   401 FAFMETIVTAITDEFPYYLRPKKAVFSAIICVALFLLGLILATDGGMYWLVLLDDYSAGFGLLVI 465

  Fly   445 CLVEIIMVAWIYGIKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFIRTITYNNIP 509
            .:...:.|:.:||||||..|::.|||.:|.||::..|..::||.::.:|..||:..:...|.:..
 Frog   466 VITFCLSVSRVYGIKNFCRDIQMMLGFKPGLYFKACWIFLSPVTLMCLLAYSILKYQPSQYGSYK 530

  Fly   510 YPQWA----IIIGWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLKP-LDWTPADPQDR 565
            :|.|:    |::|..||    |.||:.:...::::..:|.:.:::..:| :||.|:..::|
 Frog   531 FPLWSEALGILMGLLSC----MMIPIGMLVAILKEEGSLWERIRQASRPAMDWGPSMEENR 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	224/541 (41%)
slc6a7	XP_002940131.3	SLC5-6-like_sbd	37..581	CDD:444915	227/547 (41%)