Protein Alignment Ntl and slc6a2

DIOPT Version :9

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_017948962.2
• Gene: slc6a2 / 100486589
• XenbaseID: XB-GENE-486549
• Length: 624
• Species: Xenopus tropicalis
• Alignment Length: 542
• Identity: 217/542 - (40%)
• Similarity: 340/542 - (62%)
• Gaps: 12/542 - (2%)

  Fly    19 ERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVILAGIPLFYMEIL 83
            |..:.|.||..|.:|:||::|:::.:.||||||:|||::||.||||||.|.:|:||:||||||:.
 Frog    58 EGQQEREQWGKKIDFLLSVVGFSVDLANVWRFPFLCYKNGGGAFLIPYTLFLIIAGMPLFYMELA 122

  Fly    84 IGQFSSTGCTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCFFKKVPWEDCSNSW 148
            :||::..|...::::.||.||.|...:::..|...||:|||::.:..:...|..::||..|.|.|
 Frog   123 LGQYNREGAATVWKICPLFKGVGYTVILIALYVGFYYNVIIAWSLYYLVSSFTSELPWIKCGNEW 187

  Fly   149 NTDDC-----VTASDMGKQNSSDVFKTS-ADEFFHLEVLRI--STDISDLGGMVWEQLTALIITW 205
            |:.:|     :..|.:........|||: |.||:...||.:  |..|.|||...|:....||:..
 Frog   188 NSLNCTDPMLLNMSMISYNTKYSKFKTTPAAEFYERGVLHLHESNGIHDLGQPRWQLTICLIVVL 252

  Fly   206 IIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYPEWHRLLDLKVWAD 270
            |:::|.|.:|:|:.||||:.|...||::||:|||||.||||:.|||..||:.:..||.|..||.|
 Frog   253 IVLFFSLWKGVKTSGKVVWITATLPYVVLFVLLIRGITLPGSSKGISAYLHIDIKRLTDASVWID 317

  Fly   271 AAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLGFLSEKSGIP 335
            ||.|:|:.:|.|:|.::..||::.|.||...|:::..:||..||.::||.:||:||:::.|..:.
 Frog   318 AATQIFYSLGAGFGVLIAFASYNKFDNNCYRDALMTSTINCVTSFISGFAIFSILGYMAHKHNVN 382

  Fly   336 VESVATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAIMSSILDEWYWVRS 400
            :|.|||.||||.|:.|||||:.|.....||::||.||..|||||....:||:::.:.|:...::.
 Frog   383 IEDVATEGAGLVFIIYPEAISTLAGSTFWAVVFFIMLLTLGIDSAMGGMEAVITGLADDISILKR 447

  Fly   401 HKCKLTLISCLIFLGLSSIMCTNGGMFILQLFDWYSSAIAVIVICLVEIIMVAWIYGIKNFMLDV 465
            |:...||:...|....:.:..||||:::|.|.|.:::..:::...|:|.|.|:|.||:..|..|:
 Frog   448 HRKLFTLLVAFITFIFALLCITNGGIYVLTLLDTFAAGTSILFAVLIEAIGVSWFYGVDRFSEDI 512

  Fly   466 EFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFIRTITYNNIPYPQWAIIIGWASCFTSVMWIP 530
            ..|||.||.||||:.|:.|:|..::|::|.|||..:.:.|:...:|.||...|||...:|:..:|
 Frog   513 HRMLGFRPGLYWRLCWKFVSPAFLLFVVIVSIVTYKPLMYDEYKFPPWANRTGWAIALSSMTLVP 577

  Fly   531 LYIFYIMIRKRATLCDSLKKRL 552
            :||.|    |..|:..||::||
 Frog   578 IYIIY----KFLTMRGSLRERL 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:294310	216/537 (40%)
slc6a2	XP_017948962.2	SLC5-6-like_sbd	63..622	CDD:382020	216/537 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010