Protein Alignment Ntl and slc6a15

DIOPT Version :9

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_002931668.1
• Gene: slc6a15 / 100380162
• XenbaseID: XB-GENE-975885
• Length: 730
• Species: Xenopus tropicalis
• Alignment Length: 661
• Identity: 202/661 - (30%)
• Similarity: 339/661 - (51%)
• Gaps: 118/661 - (17%)

  Fly    14 KDKRIER----DENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVILAG 74
            ||:.||.    |:.|..|.||.::||:.:|:::|:||||||||||.::||.|:|:|||::::|.|
 Frog    47 KDRDIEEGSDIDDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLVPYLILLLLIG 111

  Fly    75 IPLFYMEILIGQFSSTGCTGMFR-MTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCFFKK 138
            ||:|::|:.:||....|..|::. ::|.:.|.|.|..:|..:...||:|||.:.:......|...
 Frog   112 IPVFFLELSVGQRIRRGSIGVWNYISPKMGGIGFASCIVCLFVALYYNVIIGWSLFYFSQSFQHP 176

  Fly   139 VPWEDC------SNSWNTDDCVTASDMGKQNSSDVFKTSADEFF-HLEVLRISTDISDLGGMVWE 196
            :||:.|      ||::...:|.              |:||..:: :.|.|.||..|::.||:.|:
 Frog   177 LPWDQCPLVKNASNTFVEPECE--------------KSSATTYYWYREALNISNSITEGGGLNWK 227

  Fly   197 QLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYPEWHR 261
            ....|:..||::...:::||:|.|||:||:..|||::|...|:|...|.|:..||:....|:...
 Frog   228 MTLCLLAAWILVCLAMIKGIQSSGKVMYFSSLFPYVVLTCFLVRALLLNGSVDGIRHMFTPKLEI 292

  Fly   262 LLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLG 326
            :|:.|||.:||.|:||.:|.|:||::..:|::...||...|:||:..||.|||:||..|||:|||
 Frog   293 MLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLG 357

  Fly   327 F----LSEK--------------------SGIP-------------------------------- 335
            |    ::|.                    |.:|
 Frog   358 FKANIMNENCISKNTVKIVKYLEAGNLSWSNVPHHVNFSSMSAQDYNLVYYIFQKIKEEEFDSLG 422

  Fly   336 -----VE---SVATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAIMSSIL 392
                 :|   :.:..|.||||:.:.||:...|....|::|||.||..||:.|:|..:|.|::.|:
 Frog   423 LDSCQIEDELNKSVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIITPIV 487

  Fly   393 DEWYWVRSHKCKLTLISCLIFLGLSSIMCTNGGMFILQLFDWYSSAIAVIVICLVEIIMVAWIYG 457
            |.:   :..|..||:..||:...:..:.....|.:.:.:||.||:.:.::::.::|.:.:||:||
 Frog   488 DTF---KVRKEPLTVGCCLLAFCIGLLFVQRSGNYFVTMFDDYSATLPLLIVVILENVAIAWVYG 549

  Fly   458 IKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIV------------FIRTITYNNIPY 510
            |..||.|::.|||..|..|:..:|:.::||::..:|:.|||            .....:...|.|
 Frog   550 IDKFMDDLKDMLGFTPYKYYYYMWKYISPVLLTILLMASIVQMGFSPPGYYAWIAEKASEERISY 614

  Fly   511 PQWAIIIGWASCFTSVMWIPLYIFYIMIRKRATLCD----SLK----KRLKPLDWTPADPQDRAE 567
            |.|    |.|.|.:.:::..|.:..:.|.:...|.|    ||.    ||.|.:..| ::.:|.|.
 Frog   615 PPW----GLAVCISLIVFALLPVPVVFIVRTCNLIDDSTGSLASVSYKRGKMIKET-SNLEDDAS 674

  Fly   568 YEAFRRQRRMP 578
            ....:.|..||
 Frog   675 LIHEKIQSEMP 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:294310	190/621 (31%)
slc6a15	XP_002931668.1	SLC5-6-like_sbd	61..640	CDD:382020	184/599 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920