Protein Alignment Ntl and slc6a19a.2

DIOPT Version :9

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_002665492.2
• Gene: slc6a19a.2 / 100334171
• ZFINID: ZDB-GENE-141210-16
• Length: 647
• Species: Danio rerio
• Alignment Length: 634
• Identity: 196/634 - (30%)
• Similarity: 320/634 - (50%)
• Gaps: 107/634 - (16%)

  Fly    16 KRIERDE--NRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVILAGIPLF 78
            :::|..|  .|.:|.:|::::|:.:|:.:|:||||||||||...||.||:||:|::::|.||||.
Zfish    23 EKLELQEAGERPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLL 87

  Fly    79 YMEILIGQFSSTGCTGMFR-MTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCFFKKVPWE 142
            ::|..|||....|..|::| :.|.|.|.|||.::|:.....||:.||::.:...|..|...:||.
Zfish    88 HLEFAIGQRLRRGSVGVWRSINPYLLGVGIASMLVSFIVGMYYNTIIAWVMWYFFNSFQDPLPWS 152

  Fly   143 DC----SNSWNTDDCVTASDMGKQNSSDVFKTSADEFFHLEVLRISTDISDLGGMVWEQLTALII 203
            .|    |.:....:|        :.||.|     |.|::.:.|..:..|.|.||:.|..:.:|:.
Zfish   153 QCPINGSRTGFVSEC--------ERSSPV-----DYFWYRKTLNTTPHIEDSGGLQWWMVLSLLC 204

  Fly   204 TWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYPEWHRLLDLKVW 268
            .|.:::.|.:|||::.||.||.|...|||:|.|.||||.||.|:..||||...|:.:.|||.:.|
Zfish   205 AWTVLWVCCIRGIETTGKAVYITSTLPYLVLTIFLIRGLTLKGSVSGIKFLFTPDVNELLDPQTW 269

  Fly   269 ADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLGF------ 327
            .||..|:||.....:||::..:|::|..||.:.|:|:|..||..||:.|..|::|::||
Zfish   270 LDAGAQVFFSFSLAFGGLIAFSSYNSVHNNCEQDAVIISIINGMTSIYAAIVIYSIIGFRATERF 334

  Fly   328 ----------LSEKSGIPVESVATG------------------------------------GAGL 346
                      |.....:|..|:..|                                    |.||
Zfish   335 DDCLNGNILSLLNAFDLPEGSIIEGNYTEAIQQLNISRPDIIQELQLKTCDMQTFLSQGVEGTGL 399

  Fly   347 AFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAIMSSILD------EWYWVRSHKCKL 405
            ||:.:.|||..:||..||:::||.|||.||:.::|..:|.::..:.|      .|     .|...
Zfish   400 AFIVFTEAITKMPVSPLWSVLFFIMLFCLGLSTMFGSIEGVVVPLQDLDILPKNW-----PKEAY 459

  Fly   406 TLISCLIFLGLSSIMCTNGGMFILQLFDWYSSAIAVIVICLVEIIMVAWIYGIKNFMLDVEFMLG 470
            |.:.|::....:.|.....|.:.|.|||.::.:|.:::|...|::.|:::|||..|..|::||:|
Zfish   460 TALVCVVSFAFAIIFAQGSGEYWLALFDGFAVSIPLLIIAFCEMMAVSYVYGIDRFNDDIKFMIG 524

  Fly   471 KRPTLYWRIVWQVVTPVIIIFILITSIVFIRTI-----------------TYNNIPYPQWAIIIG 518
            .:|.::|:..|::::|:|::.|.:  ..|:.|:                 |.:.:|||.|...|.
Zfish   525 HKPNIFWQATWRLISPLIVLVIFL--FYFVTTVSKKLTYIAWDPESENFPTLSVLPYPGWISAII 587

  Fly   519 WASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLKPLDWTPADPQDRAE 567
            :......|:.||......:||.|.  |   ||.......||....||.:
Zfish   588 FILAGIPVLVIPTVALVRLIRNRC--C---KKEETHATETPYSISDRVQ 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:294310	190/609 (31%)
slc6a19a.2	XP_002665492.2	SLC5-6-like_sbd	33..613	CDD:294310	188/604 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810