Protein Alignment Ntl and slc6a14

DIOPT Version :10

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_001313379.1
• Gene: slc6a14 / 100150665
• ZFINID: ZDB-GENE-130411-2
• Length: 614
• Species: Danio rerio
• Alignment Length: 594
• Identity: 231/594 - (38%)
• Similarity: 351/594 - (59%)
• Gaps: 39/594 - (6%)

  Fly    14 KDKR------IERDEN--RGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMV 70
            |||.      ::.|||  ||.|.||.|::||::|||:|:|||||||||.|:.||.||||||.:|:
Zfish    24 KDKSDKAEHVVQNDENSDRGNWSSKREYMLSMIGYAVGLGNVWRFPYLAYKHGGGAFLIPYTIML 88

  Fly    71 ILAGIPLFYMEILIGQFSSTGCTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCF 135
            .::|:|||:||...|||.|.|...:::..|:|:|.||..::|:.:...||:|||:|.|..:|..|
Zfish    89 AVSGLPLFFMESSFGQFCSQGPINVWKAVPILQGVGITMMLVSTFVAIYYNVIIAYSIYYLFASF 153

  Fly   136 FKKVPW--EDCSNSWNTDDCVTASDMG----KQNSSDVFKTSADEFFHLEV-LRISTDISDLGGM 193
            ...:||  ::|    ||    |||::.    ..:...:...|..|.:..|| |:.|:.:.:.|.:
Zfish   154 QDPLPWSIKNC----NT----TASNISTAAVNVSCGQISGQSLSEKYWDEVALQRSSSMDETGPV 210

  Fly   194 VWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYPE 258
            ||.....|:::||::...|.:||||.|||||||..|||::|.|||||||||.||..||:||:..:
Zfish   211 VWHLALCLLLSWILVGAALFKGIKSSGKVVYFTATFPYIVLLILLIRGATLEGAKDGIEFYIGSQ 275

  Fly   259 WH--RLLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVV 321
            .:  :|.:.:||.|||.|:||.:...|||::.::|::.|.||...||:::...|..||:.|||.:
Zfish   276 SNLTKLAEAEVWKDAATQIFFSLSIAWGGLMALSSYNKFYNNCYQDSIVVCVTNCGTSIFAGFAI 340

  Fly   322 FSVLGFLSEKSGIPVESVATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEA 386
            |||||.::.....||..||..|..|||:.||:|::.||:..||:::|||||..||:||.|..:|.
Zfish   341 FSVLGHMAHVYQRPVSEVADAGFALAFIAYPDALSKLPISPLWSILFFFMLITLGLDSQFAGIEV 405

  Fly   387 IMSSILDEWYWVRSHKCKLTLISCLIFLGLSSIMC-TNGGMFILQLFDWYSSAIAVIVICLVEII 450
            |.:.:||.:..|...|..|...:..|.|.|..:.| |..|::.:.|.|.:|:...::|..|:|::
Zfish   406 ISTCLLDAYPEVLKSKRGLVTTAVCIILFLLGLPCVTRAGIYWVNLIDTFSAGWILLVAGLLEVL 470

  Fly   451 MVAWIYGIKNFMLDVEFMLGKRPTLY---WRIVWQVVTPVIIIFILITSIVFIRTITYNNIPYPQ 512
            .:..:||...|:.|:|.|:|.:.:|:   ||..|..:|||::..|||.|:....:.||:::.||.
Zfish   471 GLCILYGGNRFIKDIEMMIGTKSSLFWLWWRACWFFITPVVLSIILIWSLYTFTSPTYSSVAYPD 535

  Fly   513 WAIIIGWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLKPL-DWTPADPQDRAEYEAFRRQRR 576
            |.|.:||.....|:||||:...:.:.:.|..|...:|....|. ||.|       ..|..|.:|.
Zfish   536 WGISLGWCITAFSLMWIPIVAVWKVCKARGGLWQRIKSACSPTEDWGP-------YLECHRGERY 593

  Fly   577 MPGFMSDTD 585
              |...:||
Zfish   594 --GTRGETD 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	215/542 (40%)
slc6a14	NP_001313379.1	SLC6sbd_ATB0	42..612	CDD:271391	225/576 (39%)