Protein Alignment Ntl and slc6a8l

DIOPT Version :10

• Sequence 1: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_012815966.1
• Gene: slc6a8l / 100127575
• XenbaseID: XB-GENE-5768780
• Length: 654
• Species: Xenopus tropicalis
• Alignment Length: 575
• Identity: 224/575 - (38%)
• Similarity: 336/575 - (58%)
• Gaps: 41/575 - (7%)

  Fly    24 RGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFLIPYLLMVILAGIPLFYMEILIGQFS 88
            |..|..:.:||:|.:|:|:|:|||||||||||::||..|||||||:|.:.|||:|::||.:|||.
 Frog    61 RETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYLLIVFVGGIPVFFLEIALGQFM 125

  Fly    89 STGCTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPIRMIFYCFFKKVPWEDCSNSWNT--- 150
            ..|....:.:.||.||.|.|.:|:..:|..||.:|:.:.:..:.:.|...:||..|.|.||:
 Frog   126 KQGGIAAWNIAPLFKGLGFASMVIVFFCNTYYIMILVWGLYYLVHSFTNTLPWATCGNPWNSKEC 190

  Fly   151 ------DDCVTASDMGKQNSSDVFKTSAD----------EFFHLEVLRISTDISDLGGMVWEQLT 199
                  |.|...|.....:|..:...|.|          ||:..:||:||..:::.|.:.|:.:.
 Frog   191 TEVFLVDHCNNGSLANVTDSGTLVNISCDALVNKRSPVIEFWERKVLQISGGLNEPGQLNWQMIL 255

  Fly   200 ALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLFILLIRGATLPGAWKGIKFYLYPEWHRLLD 264
            .|:.||:|:|||:.:|:||.|||||||..|||::|.:||..|.|||||..||.:||.|.|.:|.:
 Frog   256 CLMATWVIVYFCIWKGVKSTGKVVYFTALFPYVVLIVLLAHGVTLPGALDGIVYYLKPNWSKLAE 320

  Fly   265 LKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAKCDSVLIVSINVFTSLLAGFVVFSVLGFLS 329
            .:||.||..|:||....|.|.:..:.|::.|.||...|:.::.:||..||..|||||||||||::
 Frog   321 AQVWIDAGTQIFFSYAIGLGALTALGSYNRFHNNCYRDAYILAAINSTTSFFAGFVVFSVLGFMA 385

  Fly   330 EKSGIPVESVATGGAGLAFVTYPEAIALLPVPQLWALMFFFMLFLLGIDSVFVQLEAIMSSILDE 394
            .:.|:.:..||..|.||||:.||:|:.|:|...:||.:|||||.:||:||.||.:|..::.|:|.
 Frog   386 SEQGVHISKVAESGPGLAFIAYPKAVTLMPFAPIWAALFFFMLLILGLDSQFVGVEGFITGIMDL 450

  Fly   395 W-----YWVRSHKCKLTLISCLIFLGLSSIMCTNGGMFILQLFDWYS-SAIAVIVICLVEIIMVA 453
            :     .:||..  ....:.||:...:...|.|.|||::.||||:|| |.|.::.....|.:::|
 Frog   451 FPQPINGFVRRE--VTAALCCLVCFIIDLSMVTEGGMYVFQLFDYYSASGITLLWQAFWECVVIA 513

  Fly   454 WIYGIKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIFILITSIVFIRTITYN-NIPYPQWAIII 517
            |:||...||.|:..|:|.||..|.:..|.|:||::.:.|.:..:|..:.:||| :..||.|...|
 Frog   514 WVYGADRFMDDIARMIGYRPLPYMKWCWSVLTPLVCVGIFVFHVVNYKPLTYNKSYVYPWWGEAI 578

  Fly   518 GWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLKPLDW----TPADPQDRAEY 568
            ||:....|::.|||.:...|:|.:.    ||::|     |    ||.......||
 Frog   579 GWSLALASMLCIPLTVVCKMLRSKG----SLRER-----WHLLTTPVWGHHHLEY 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	219/555 (39%)
slc6a8l	XP_012815966.1	SLC6sbd_CT1	61..654	CDD:271397	224/575 (39%)