DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tep3 and AI182371

DIOPT Version :9

Sequence 1:	NP_523507.2	Gene:	Tep3 / 34045	FlyBaseID:	FBgn0041181	Length:	1469	Species:	Drosophila melanogaster
Sequence 2:	XP_017174840.1	Gene:	AI182371 / 98870	MGIID:	2138853	Length:	366	Species:	Mus musculus

Alignment Length:	364	Identity:	79/364 - (21%)
Similarity:	135/364 - (37%)	Gaps:	103/364 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 QGLYSIIAPNTLRPNSQFHVAVSLHNAPESATFKVGILGSSYTD------FKTVELRPFSTQLLH 86
            |..|.|..|...|..:..:|.|..|...|:  |...:...||.|      |.||.|.|.:    .
Mouse    39 QTRYIISTPIVFRVGAPENVTVQAHGHTEA--FDTTVSVKSYPDENVRYSFSTVNLSPEN----K 97

  Fly    87 FEIPALRTDRYRLTAEGLGGVQFTNE----TQLHFESKQ--------HTVLVQTDKSIYKPGDLV 139
            |:..|:.|.:.:..:||..  .|:|.    ...||...:        .::.||||||:|.|...|
Mouse    98 FQNTAILTIQAKQLSEGQN--SFSNSYLEVVSKHFAKLEIVPIIYDNDSLFVQTDKSVYTPQQPV 160

  Fly   140 HYRVLILDANLKPA-RGYGRVHVDIKDS------GDNI--IRSYKDIRLTNSIYSNELRLSDSPR 195
            ..||..::.:|:|| |......:|.:.|      |:|:  |.|:.|..:.:           :|:
Mouse   161 KVRVYSVNDDLEPATRETVLTFIDPEGSQVDTIEGNNLTGIASFPDFEIPS-----------NPK 214

  Fly   196 FGTWSIVV----DVSD--------QEHTQTFEILDHILPKFVVDIDTPKHAIY------------ 236
            .|.|::..    |.|.        :|:.:|:.|  .|:|...:..:..|...:
Mouse   215 HGRWTVKAKYREDASKTGTTYFEVKEYDKTYRI--SIMPTIDLQPEVEKQEAHGMCLHQPTECLR 277

  Fly   237 -KDGKIAATVRAHYAFGQPIVGE-----ATLSIYPTFFGSLQPFVNDLITRKVVPIDGNAY---- 291
             |..:.|:|      :..|::.:     |..:|:.|       .|......|:.||...|:
Mouse   278 QKINEQAST------YKHPMIKKCCYDGARYNIHET-------CVQRAARVKIGPICVKAFTLCC 329

  Fly   292 ------FEFDIENELHLKQDYERQYLLDALVEEKSTGSV 324
                  .|......:||.....:.:.:  ::|.|::|.|
Mouse   330 NMAHQILENSTFKHIHLSSHCFKSFKM--ILENKASGHV 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tep3	NP_523507.2	A2M_N	124..215	CDD:280081	29/111 (26%)
		A2M_N_2	448..573	CDD:285005
		A2M	697..787	CDD:278630
		A2M_2	918..1203	CDD:239227
		A2M_comp	967..1200	CDD:284982
		A2M_recep	1313..1402	CDD:284981
AI182371	XP_017174840.1	MG1	42..138	CDD:375333	26/103 (25%)
		A2M_N	145..238	CDD:376626	27/103 (26%)
		ANATO	279..347	CDD:237984	14/80 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840000
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2373
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740