Protein Alignment Tep3 and Tep1

DIOPT Version :10

• Sequence 1: NP_523507.2
• Gene: Tep3 / 34045
• FlyBaseID: FBgn0041181
• Length: 1469
• Species: Drosophila melanogaster
• Sequence 2: NP_523578.1
• Gene: Tep1 / 34937
• FlyBaseID: FBgn0041183
• Length: 1354
• Species: Drosophila melanogaster
• Alignment Length: 1444
• Identity: 460/1444 - (31%)
• Similarity: 736/1444 - (50%)
• Gaps: 128/1444 - (8%)

  Fly    14 LILVTACLLC--QTSAQGLYSIIAPNTLRPNSQFHVAVSLHNAPESATFKVGILGSSYTDFKTVE 76
            |||.:..|.|  .::|.||||::||.|||.||.::|.|::||...:....|.:.|.|....|.|:
  Fly     4 LILSSTILHCVLLSNANGLYSVLAPKTLRSNSAYNVVVAIHNTTRTTEVSVSLTGPSLNSRKYVD 68

  Fly    77 LRPFSTQLLHFEIPALRTDRYRLTAEGLGGVQFTNETQLHFESKQHTVLVQTDKSIYKPGDLVHY 141
            ::..|::.:.|:||.|....|.|...|.||::|.|.|:|.|....:.:.:|:||:.|||||.:.:
  Fly    69 VQSMSSKSVRFDIPKLTEGDYELKVMGSGGIEFQNSTKLSFAPDLNWLYIQSDKATYKPGDKIQF 133

  Fly   142 RVLILDANLKPARGYGRVHVDIKDSGDNIIRSYKDIRLTNSIYSNELRLSDSPRFGTWSIVVDVS 206
            |||.||.|.:||.....:.::|:|...|:|:|:|||:....:||.||:|||.|..|.|::...|.
  Fly   134 RVLFLDKNTRPAVIDKPIKIEIRDGDQNLIKSWKDIKPAKGVYSGELQLSDRPVLGNWTVTATVQ 198

  Fly   207 DQEHTQTFEILD-HILPKFVVDIDTPKHAIYKDGKIAATVRAHYAFGQPIVGEATLSIYPTFFGS 270
            |:.......::| :::|||.|.:.|.|:.....|.|.||::|.|.|.:|:.|.    :..|..||
  Fly   199 DEGKVTNVLVVDKYVVPKFEVVVLTAKNVAASAGYIRATIKARYTFKKPVKGH----VVATIEGS 259

  Fly   271 LQPFVNDLITRKVVPIDGNAYFEFDIENELHLKQDYERQYLLDALVEEKSTGSVQNYSTVLTLHL 335
                    .|.:.:||||....||.|      ....:|...:.|:|.|:.|....|.:..:|:|.
  Fly   260 --------STEQSLPIDGEVNVEFPI------SATAKRLLKITAIVTEELTDIKHNGTAYVTVHQ 310

  Fly   336 NHYRVEAVKVPSYYIPGVPFEATARIARNDGGQLRDFNPQITAYLTNVYGSSEMYNRTAYSLDAS 400
            :.:::|.:..|::|.|||..|....:...||..:.|              ||:|.|........|
  Fly   311 HRHKLEDLFWPTHYRPGVSSEFKTVVRNLDGSPVMD--------------SSKMVNFNVLCCQVS 361

  Fly   401 GEIKMKFTVPIGDR-----DEFHSIIV--------DYQGVISEVGKIPSKHLHSKNYITAKVLND 452
            ..........|...     :...|.:|        :.:..|.::.|.....:::|.....|:|
  Fly   362 KNFSASLQNSIATEHIMLPETCQSCLVTSTFDTAENIERYIYKLNKPLMIAINTKKPQLRKLL-- 424

  Fly   453 RPTVNQEISVVVRSFAPIKYFMYQVVGRGDIILSRNVDV-APGTFHTIKFLASFAMMPRANLLVY 516
                  :|:::..::.|  ||:..||.||:|:||...:: .......|:|..:||::|:|.:.|:
  Fly   425 ------KINIISDTYLP--YFILTVVARGNIVLSLFQEMKEKKKSQEIEFEPTFALVPQATIFVH 481

  Fly   517 TVIDGEFVYDEQVIQLEENLLNAVQVDAPIRAPPGQDIDIGISTKPYSYVGLMLVDQNANDLRSG 581
            .:|||..:.||:.:.:|.:..|.:::.....|.|..::.:.:.|.|:|:|||:.|||:...||||
  Fly   482 YIIDGVLMSDEKTVDIERDFENTIEILTTNEALPRDEVSLKVKTNPHSFVGLLGVDQSVLLLRSG 546

  Fly   582 HDLTHKRLMDALRSYELSDVNTPMGSPGKESGVITMSNTD-YFIEKEAESNPALDREVSTGPEED 645
            :||....:::.|.:|....|            ::|.:|.: |.......:||....  .||....
  Fly   547 NDLNRDLILNNLATYSTDLV------------ILTNANINIYRSSGGCYTNPGYTN--CTGSLIG 597

  Fly   646 KLTTVRKTDIGPAHKIEVNTLPPGKGRYAFSYTPKPFWHNPRVHVMRDPA-----DTWLFLNIS- 704
            :  |:.|.:             |.|     :..|.|...:.|......|.     :||||.||:
  Fly   598 R--TMFKNE-------------PTK-----NSGPVPIVGSTRAQASLPPVRKLFPETWLFSNITD 642

  Fly   705 ASSDGRNSIHRRIPSEMTSWVVSAFALDPVNGLGLSPPNGKLEAYKEFYISTELPYSIKRDELIA 769
            ..::|...|...:|..:||||::.|:|.|.:||.::....::..::.|:|:|.||||:||.|:||
  Fly   643 VGANGEYIIKETVPDTLTSWVITGFSLSPQSGLAVTRNPSRIRVFQPFFITTNLPYSVKRGEVIA 707

  Fly   770 IPFVVHNNRDSDLNVEVTFYNSALDFDFPQLDPKATNQPKVELYRRRSLQVPGRSARSVSFIVTP 834
            ||.:|.|....|:..:|...||...::|.:...|..:|....:.|:::|.:|..:.|.:||::.|
  Fly   708 IPVIVFNYLGMDVKAKVLMDNSDGQYEFIETTNKNVSQYLRGVRRKKTLWIPANTGRGISFMIRP 772

  Fly   835 KRVGPLLVKAMAASSQAGDTVEQNLLVEHPGAMERINRGFLFELNSNAQNRRNV-----TIAVPR 894
            |:||...:|..|.|..|||.:.|.|.||..|..:.:|:..|  :|....|||::     ||.:.:
  Fly   773 KKVGLTTLKITAISKYAGDRLHQILKVEADGVQKYVNKAVL--INVQRLNRRSLAPPEKTIIIEK 835

  Fly   895 --NAIPESTRIEVSAVGDLIGSLVGNLDSLILLPTGCGEQTMVNFVPNLIVLRYLGRLRQLTPEV 957
              |.|..|..:|....|......:.:||.|:.||.|||||.|.||||:::.|.||....:...|:
  Fly   836 ADNVIEGSETVEFEVCGTSQAPQLEHLDDLVHLPCGCGEQNMFNFVPSILALSYLKAKNRQDQEI 900

  Fly   958 ELRATNNLAIGYQRILYYRHENGAFSAFGLDIKRSSTWLTAYVARSLRQAAPFTQVDSNVLQKAL 1022
            |.:|...:..|||..|.|:..:|:|||:|......||||||||.||..|||.:..:|.|||...|
  Fly   901 ENKAKRYVETGYQIELNYKRNDGSFSAWGQHDALGSTWLTAYVIRSFHQAAKYIDIDKNVLVAGL 965

  Fly  1023 TYLGSVQSANGGFEERGDVFERFGDDGISLTAFVTLALMENVDLYPEYRNNINKALDFITRGLDG 1087
            .:|.|.||.:|.|:|.|.|........::||:||.|...||.:..|:|::.|::|::|:...:..
  Fly   966 DFLVSRQSTDGKFKELGMVIHNSHGSPLALTSFVLLTFFENEEYMPKYKHVIDRAVEFVVTEVHQ 1030

  Fly  1088 SSNLHAMAIGTYVLSRANHNAKAAFLQRLDSMATNKDGLKWWNKTAPAGEQQSPWYNATRSVNIE 1152
            |:..:.:||....||.|.:......|.:||.:||.:...|||..:           :..:|..:|
  Fly  1031 SNEPYDLAIAALALSLARNRNAYKVLDKLDKLATRRGDHKWWTGS-----------DKCKSSEVE 1084

  Fly  1153 ISAYAALALLENNLVGDALPVLNWLMDQRNPKGGFVASQDTVVGLQALLMFAERFSSQGNNLQIG 1217
            .::|..|||||:|:..:..|:::||:.:||..||||:|||||||:.||..:..:..:....:.|.
  Fly  1085 TTSYVLLALLEHNISDEPKPIVDWLISKRNSNGGFVSSQDTVVGIMALTKYELQSHASTEAIDIE 1149

  Fly  1218 FHYGEGAETIINVNAENSLALQTVELPNNLKNLSVSATGRGMALAQVSYTYNTNVTSAWPRFVLD 1282
            |.:....:..:.|..||...:||.:||.|...:.:.|.|:|.|..|::|.||.....|.|.|.|.
  Fly  1150 FWHLNEDKKHVRVTKENEFKVQTHQLPENTNEVKLLAKGQGRAQVQLTYRYNVATKEARPSFKLT 1214

  Fly  1283 PTVNRNSHADYLHLSACASFVSV-VGENEQRSNMAVMEVHLPSGFVVDRDTLPTLESSERIKKVE 1346
            .|| :.||...|.|..|.::..: ..|..:.:|||:|:|.||||:|.|.:....:|:...:|:||
  Fly  1215 TTV-KKSHKGRLILGICGTYTPIAASERNKTTNMALMQVQLPSGYVCDIEPFADIEAISDVKRVE 1278

  Fly  1347 TQNRNTKVVIYFDYL---DRREVCPTLHAYKTVKVTKHRPVAVVMYDYYDSARRARQFYRAPKSN 1408
            |:|.:|:|.|||:.|   ||:  |.||.|..|..|...:|..|.:||||.:.|.|.:||....|
  Fly  1279 TKNEDTEVHIYFEKLSPGDRK--CLTLEAIYTHAVANLKPSWVRLYDYYATERSATEFYHVDTS- 1340

  Fly  1409 ICDICEHANCGDLC 1422
            :||||....||::|
  Fly  1341 LCDICHGNECGNMC 1354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep3	NP_523507.2	YfaS	<128..1399	CDD:441940	407/1303 (31%)
		A2M_2	918..1203	CDD:239227	111/284 (39%)
Tep1	NP_523578.1	YfaS	<117..1200	CDD:441940	356/1171 (30%)
		A2M_2	859..1135	CDD:239227	111/286 (39%)
		A2M_recep	1243..1336	CDD:462226	40/94 (43%)