DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tep3 and LOC101732535

DIOPT Version :9

Sequence 1:	NP_523507.2	Gene:	Tep3 / 34045	FlyBaseID:	FBgn0041181	Length:	1469	Species:	Drosophila melanogaster
Sequence 2:	XP_031761615.1	Gene:	LOC101732535 / 101732535	-ID:	-	Length:	591	Species:	Xenopus tropicalis

Alignment Length:	642	Identity:	178/642 - (27%)
Similarity:	273/642 - (42%)	Gaps:	92/642 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   729 FALDPVNGLGLSPPNGKLEAYKEFYISTELPYSIKRDELIAIPFVVHNNRDSDLNVEVTFYNSAL 793
            |.|....|||::.......:...|::...:|:|..|.|::.:...|.|..:..:.|.||...|.
Frog     2 FCLSEGKGLGVTKYPSNFTSSLPFFVEVSVPFSFTRGEMLLLRAFVSNYLNQCIKVRVTLQPSK- 65

  Fly   794 DFDFPQLDPKATNQ----PKVELYRRRSLQVPGRSARSVSFIVTPKRV-------GPLLVKAMAA 847
              |:..:..:.|..    ||..  ...|..|...|...:||.||.:..       ||    ....
Frog    66 --DYTAILQEGTQDMCVCPKGR--ASYSWNVTANSLGVISFNVTVQMTFIGATCGGP----PNTT 122

  Fly   848 SSQAGDTVEQNLLVEHPGAMERINRGFLFEL-NSNAQNRRNVTIAVPRNAIPESTRIEVSAVGDL 911
            .....|||.:.::||..|..:.:....|..: .:|||...::|  .|.|.:..|.:..|:.:||.
Frog   123 QPPRSDTVIKTVIVEAEGIEKEVTYSNLVCVEGNNAQIPFSIT--PPANMVKGSAKASVTVIGDP 185

  Fly   912 IGSLVGNLDSLILLPTGCGEQTMVNFVPNLIVLRYLGRLRQLTPEVELRATNNLAIGYQRILYYR 976
            :|..|.|.||||.:|||||||.:|..:|...||.||....|||.|::.:|...:|.||.|.|.::
Frog   186 LGHAVNNPDSLIQMPTGCGEQNLVKLLPIPAVLAYLNCSGQLTKEIQDKAVQYMATGYVRQLGFK 250

  Fly   977 HENGAFSAFGLDIKRSSTWLTAYVARSLRQAAPFTQVDSNVLQKALTYLGSVQSANGG-FEERGD 1040
            ..:|.|||||......|:||||....:.::...:|.||..|:.:||..|...|....| |:..|.
Frog   251 RYDGTFSAFGQRDPEGSSWLTALSLYTFQKIKQYTLVDPTVINQALIALEKSQDLQSGCFKVSGT 315

  Fly  1041 VF--ERFG--DDGISLTAFVTLALMENVDLYPEYRNNINKALDFITRGLDGSSNLHAMAIGTYVL 1101
            :|  |..|  ::.||.||:|...|||.  .||..:..:...|..:.........|:.:|:..|..
Frog   316 LFNSELKGGAENEISFTAYVVAILMET--NYPGAQTLLRNGLGCLDAASRREQTLYNLALLFYAF 378

  Fly  1102 S-RANHNAKAAFLQRLDSMATNKDGLKWWNKT-APAGEQQSPWYNATRSVNIEISAYAALALLEN 1164
            | ..|...:.|.|.:|..:|.:::|...|.:| .|..|:...:|....|.:|||:.|..|...:
Frog   379 SLSGNEERRNATLAKLKKLAIHENGGIHWERTDKPIAEKYPFFYAPPPSADIEITGYVLLGFTK- 442

  Fly  1165 NLVGDA---------LPVLNWLMDQRNPKGGFVASQDTVVGLQALLMFAERFSSQGNNLQIGFHY 1220
               |.|         ..:..||:.|:|.:|||.::.||||.||||..::.....:|...::....
Frog   443 ---GPAPSQEEKSYMTQIAVWLVRQQNSQGGFRSTADTVVALQALAEYSCLVYKKGATNRVTVSL 504

  Fly  1221 GEGAETIINVNAENSLALQTVELPNNLKNLSVSATGRGMALAQV---------SYTYNTNVTSAW 1276
            ........||...|.|.:|...||:...|.|...:|.|..|.|:         :::||
Frog   505 ARQVIATFNVQPSNRLLVQRRMLPSQQGNYSFGVSGNGCCLIQIRRTIIPINLTFSYN------- 562

  Fly  1277 PRFVLDPTVNRNSHADYLHLSACASFVSVVGENEQRSNMAVMEVHLPSGFVVDRDTL 1333
                                          |:..| |||||:::.|.||:.|...:|
Frog   563 ------------------------------GKKNQ-SNMAVVDMKLLSGYSVQYQSL 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tep3	NP_523507.2	A2M_N	124..215	CDD:280081
		A2M_N_2	448..573	CDD:285005
		A2M	697..787	CDD:278630	13/57 (23%)
		A2M_2	918..1203	CDD:239227	102/300 (34%)
		A2M_comp	967..1200	CDD:284982	76/248 (31%)
		A2M_recep	1313..1402	CDD:284981	10/21 (48%)
LOC101732535	XP_031761615.1	A2M	<2..61	CDD:395153	14/58 (24%)
		A2M_2	189..487	CDD:239227	103/303 (34%)
		A2M_recep	568..>588	CDD:400149	9/19 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177369at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010