Protein Alignment Tep3 and LOC100495827

DIOPT Version :10

• Sequence 1: NP_523507.2
• Gene: Tep3 / 34045
• FlyBaseID: FBgn0041181
• Length: 1469
• Species: Drosophila melanogaster
• Sequence 2: XP_017945568.2
• Gene: LOC100495827 / 100495827
• XenbaseID: XB-GENE-29082831
• Length: 1475
• Species: Xenopus tropicalis
• Alignment Length: 1565
• Identity: 391/1565 - (24%)
• Similarity: 639/1565 - (40%)
• Gaps: 308/1565 - (19%)

  Fly    31 YSIIAPNTL-RPNSQFHVAVSLHNAPESATFKV--GILGSSYTDFKTVELRPFSTQLLHFEIPAL 92
            |::|.|:.| .|:|: .|.|.|..|...:..:|  .:...:.|..:.:..:......:.||:|..
 Frog    26 YAVIFPSELVAPHSE-QVCVHLSGAERDSRIQVTLNMAKQNLTVIEKILQQKLFFSCVTFEVPPP 89

  Fly    93 RTDRYRLTAEGL---GGVQFTNETQLHFESKQHTVLVQTDKSIYKPGDLVHYRVLILDANLKPAR 154
            .......|.|.|   .|...||.:::....::.:..:||||::|||||.|..||:.|..||:|..
 Frog    90 SEWDEVATMEILIENAGETVTNSSKVLVRKRRTSTFIQTDKALYKPGDTVQIRVVSLKENLQPEE 154

  Fly   155 GYGRVHVDIKDSGDNIIRSYKDIRLTNSIYSNELRLSDSPRFGTWSIVVDVSDQEHTQTFEILDH 219
            ....| :.|::.....|..:.::.|...|....|.||.:|.||.:||  :|...||  .|.:..:
 Frog   155 TQFPV-IYIQNPEWKRIAQWLNVTLKQGIAELSLPLSPTPLFGQYSI--NVGGIEH--HFSVAGY 214

  Fly   220 ILPKFVVDIDTPKHAIYKDGKIAATVRAHYAFGQPIVGEATLSIYPTFF-----GSLQPFVNDLI 279
            .||.|.|....||.......:....:...|.:||.:.|.....:....|     |..|.| .||.
 Frog   215 ALPTFEVVFQFPKAVFSNSEQFQLQICGRYPYGQAVQGTYQAMVCRRAFLLYWSGHFQNF-TDLC 278

  Fly   280 TRKVVPID-----GNAYFEFDIENELHLKQDYER------QYLLDALVEEKSTGSVQNYS----T 329
                  :|     |:|....     |.:|.|..|      :..|:.:......|:...||    |
 Frog   279 ------VDFSGKLGHAGCSI-----LQVKSDTFRIAYNTHEMYLEGVATITGEGTGMKYSGRGGT 332

  Fly   330 VLTLHLNHYRVEAVKVPSYYIPGVPFEATARIARNDGGQLRD------FNP-QITAYLTNVYGSS 387
            .::..|...|.....|.  |.||:|:....::...:...|.:      .|| .||..|.     |
 Frog   333 TISHKLKSCRFLDGDVT--YKPGIPYRGAIKVGDGNDDPLPNEIVSLTINPMNITENLV-----S 390

  Fly   388 EMYNRTAYSLD--ASGEIKMKFT----------------VPIGDRDE-----FHSIIVDYQGVIS 429
            :.....::.||  ::.|.|::.|                ||:..:|.     |.|:...:..:.|
 Frog   391 DENGLVSFRLDNTSAWEGKLRLTASPQTVNTVDMYSGLIVPVFGKDSLELKPFESLSKSFLKLHS 455

  Fly   430 EVGKIP---------------------SKHLHSKNYITAK-VLNDRPTVNQEISVVVRSFAPIKY 472
            :.|.:|                     :||:.....|.:| .:.|..:|...|:......:.::
 Frog   456 QQGALPCEGQRDVRVEYIIPNSALGMEAKHMELHYLIISKDSIKDSGSVEVPITSEGGGSSELR- 519

  Fly   473 FMYQVVGRGDIILSRNVDVAPGTFHTIKFLASFAMMPRANLLVYTVIDGEFVYDEQVIQLEENLL 537
                  |...|.|:.:.||:|    |::.|. |..:|          :||.|.|....:|:....
 Frog   520 ------GEVSIKLTLSADVSP----TLRALV-FIFLP----------NGELVADSATFKLQSCFK 563

  Fly   538 NAVQVD-APIRAPPGQDIDIGISTKPYSYVGLMLVDQNAN---DLRSGHDLTHK----------- 587
            |.|.|. :|....||.|:.:.:.....|..||.:||:...   |:.:  |..||
 Frog   564 NKVSVGFSPDEVLPGADVSLQVQAAAGSLCGLRVVDKTVEPEVDVTA--DKIHKLFPYFTGTHDY 626

  Fly   588 RLMDALRSYELSDVNTPMGSPGKESGVITMSNTDYFI--------------------------EK 626
            |:.||       |.|.|:             |..|.|                          |:
 Frog   627 RIKDA-------DDNCPL-------------NQKYHIDVYSLFKDMRLKIVTNAYNKRPSKCWEE 671

  Fly   627 EAESNPALDREVST----------GPEEDKLTTVRKTDIGPAHK------IEVNTLPPG------ 669
            :.|....:.||:..          |...|::..: .|.|.|..:      :.|.::|..
 Frog   672 DLEEMMYIPREIVIKHTKAVFELFGVNPDRILEI-PTHIEPTPRLSRVEDLSVISIPNNFRDKDE 735

  Fly   670 --KGRYAFSYTPKPFWHNPRVHVMRDPADTWLFLNISASSDGRNSIHRRIPSEMTSWVVSAFALD 732
              ||.........|              :||::...:....||..:|...|..:|.|...||.:.
 Frog   736 ITKGAAEIIPVSLP--------------ETWIWELAAVGESGRAEVHGSAPDTITEWNAGAFCMG 786

  Fly   733 PVNGLGLSPPNGKLEAYKEFYISTELPYSIKRDELIAIPFVVHNNRDSDLNVEVTF--------- 788
            | :|.|:|||. .|.|:..|::...||||:.|.|..::...|.......:.|:.|.
 Frog   787 P-SGFGISPPT-SLRAFPPFFVELTLPYSVVRGESFSLKASVFKYLKHCIKVQTTLLPSQELELE 849

  Fly   789 ------YNSALDFDFPQL---DPKATNQPKVEL-YRRRSLQVPGRSARSVSFIVTPKRVGPLLVK 843
                  |:|.|..:..:.   :.||:|..:|.: .|..:|.........:.  :.||
 Frog   850 PCADCQYSSCLCAEERKTFYWNLKASNLGEVNVTVRTEALNTQDMCNNEIP--IVPK-------- 904

  Fly   844 AMAASSQAGDTVEQNLLVEHPGA--MERINRGFLFELNSNAQNRR-NVTIAVPRNAIPESTRIEV 905
                 ....:||.:.|||: ||.  :|:.:...:...|:.|.::: .:::.||.|.:..|.|..:
 Frog   905 -----EGHSNTVTKPLLVQ-PGGILVEKSHNSLICRQNAKAHSKKEEISLKVPENILKGSERAYI 963

  Fly   906 SAVGDLIGSLVGNLDSLILLPTGCGEQTMVNFVPNLIVLRYLGRLRQLTPEVELRATNNLAIGYQ 970
            :.:|||:|:.:.|||.|:.:|.|.|||.|:.|.|::.:|:||....||:||::.:|...|..|||
 Frog   964 TVLGDLMGTAMQNLDRLLAMPFGNGEQKMILFAPSIYILQYLENTHQLSPEIQSKAKRLLTNGYQ 1028

  Fly   971 RILYYRHENGAFSAFGLDIKRSSTWLTAYVARSLRQAAPFTQVDSNVLQKALTYLGSVQSANGGF 1035
            ..|.|:|.:|::..|.....:.::||||||.:|..:|.|:..:|...:.:::::|...:...|.:
 Frog  1029 IQLTYKHYDGSYILFRSRNPKGNSWLTAYVTKSYNKARPYISIDEAHIGQSVSWLSYYKRKTGNY 1093

  Fly  1036 EERGDVFERFG--------DDGISLTAFVTLALMENVDLYPEYRNNINKALDFITRGLDGSSNLH 1092
            ..|  |.:||.        ||.:||:|::|:|||:..  .|:....::.||..:....:..|:.:
 Frog  1094 FRR--VGKRFNNALKGGMHDDELSLSAYITIALMDAG--LPKTDTLLSHALYCLREAAENVSSAY 1154

  Fly  1093 AMAIGTYVLSRANHN-AKAAFLQRLDSMATNKDGLKWWNKTAPAGE--QQSPWYNATRSVNIEIS 1154
            ..|:..|..:.:..| .:...|.:|:..|..|||...|.: .||.|  ..|.|:. |.|..:|::
 Frog  1155 TQALLAYTFTLSGDNKLREMLLAKLEEKAIRKDGQLHWEQ-IPASEAFNLSSWHR-TPSAEVELA 1217

  Fly  1155 AYAALALLENNLVGD--ALPVLNWLMDQRNPKGGFVASQDTVVGLQALLMFAE-RFSSQGN---N 1213
            :|..|||........  |..::|||..|:||.|||.::|||||.||||..:|| .|:.:|:   .
 Frog  1218 SYVLLALPSQTKKDQRKASEIVNWLSKQQNPYGGFYSTQDTVVALQALAKYAEATFTDKGDVTVT 1282

  Fly  1214 LQIGFHYGEGAETIINVNAENSLALQTVELPNNLKNLSVSATGRGMALAQVSYTYN-----TNVT 1273
            .:||||..      .:|:..|.|.||...||:.....|:||||.|....|....||     :|.|
 Frog  1283 SKIGFHQQ------FHVDQTNRLLLQKASLPDIPGEYSLSATGSGCVYVQTVLRYNIPPPRSNAT 1341

  Fly  1274 SAWPRFVLDPTVNRNSHADYLHLSACASFVSVVGENEQRSNMAVMEVHLPSGFVVDRDTLPTLES 1338
            .: .|....|..........:.:.....:....||    ||:|::||.:.|||...|.|...|.|
 Frog  1342 FS-VRVETQPKQCPQEPMKQMRIDIYIQYTGSRGE----SNLALVEVKMLSGFFPVRSTTHQLVS 1401

  Fly  1339 SERIKKVETQNRNTKVVIYFDYLDRREVCPTLHAYKTVKVTKHRPVAVVMYDYYDSARRARQFYR 1403
            |..||..|||  |..:.:|.:.|....|..:....:.::|...:|..|.:||||:.|..|...|.
 Frog  1402 SNTIKHSETQ--NDVLALYLNELGHDPVHLSFTVEQDIEVKNLKPAMVKVYDYYEPAEHAVTEYN 1464

  Fly  1404 APKSN 1408
            :|.|:
 Frog  1465 SPCSS 1469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep3	NP_523507.2	YfaS	<128..1399	CDD:441940	365/1451 (25%)
		A2M_2	918..1203	CDD:239227	99/297 (33%)
LOC100495827	XP_017945568.2	YfaS	<125..1462	CDD:441940	367/1456 (25%)
		A2M_2	973..1268	CDD:239227	99/300 (33%)