Protein Alignment Tep3 and LOC100491968

DIOPT Version :9

• Sequence 1: NP_523507.2
• Gene: Tep3 / 34045
• FlyBaseID: FBgn0041181
• Length: 1469
• Species: Drosophila melanogaster
• Sequence 2: XP_031755349.1
• Gene: LOC100491968 / 100491968
• -ID: -
• Length: 1653
• Species: Xenopus tropicalis
• Alignment Length: 1615
• Identity: 378/1615 - (23%)
• Similarity: 662/1615 - (40%)
• Gaps: 294/1615 - (18%)

  Fly    18 TACLLCQTSAQGLY----SIIAPNTLR-------------PNSQFHVAVSLHNAPES----ATFK 61
            |.||.......|.|    ::|.|:.||             .||.|...:.:.:.|:.    |:.|
 Frog     5 TLCLSLLLLVAGSYAQQCTLITPSLLRVETEETIVVDAQGHNSAFDANILIQDFPQKKLSLASAK 69

  Fly    62 V------GILGSSYTDFKTVELRPFSTQLLHFEIPALRTDRYRLTAEGLGGVQFTNETQLHFESK 120
            |      |.|||......:.:| |..|          |.:::...:...|.........|.:.|.
 Frog    70 VSLNNSNGFLGSGTVKIPSDQL-PKET----------RNNQFVYVSVSSGSCTLEKVVLLQYSSG 123

  Fly   121 QHTVLVQTDKSIYKPGDLVHYRVLILDANLKPARGYGRVHVDIKDSGDNIIRSYKDIRLTNSIYS 185
            .  :.:||||:||.||..|.|||..::..:.|. ....|...:...|..::|........:.|.|
 Frog   124 Y--IFIQTDKTIYTPGSKVMYRVFSMNYKMYPV-AKPMVIEFVNPDGIVVMRESIHPASKSGILS 185

  Fly   186 NELRLSDSPRFGTWSIVV---DVSDQEHTQTFEILDHILPKFVVDIDTPKHAIYKDGK-IAATVR 246
            ....|.:....|.|:|..   |...|.:|..||:.:::||...:.:.......|.|.| .:..:.
 Frog   186 ETHDLPELVSLGVWTISAKYEDTPQQNYTTNFEVKEYVLPTIEIILKPESSFFYTDAKTFSVNIE 250

  Fly   247 AHYAFGQPIVGEATLSIYPTFFGSLQPFVNDLITRKVVPI---DGNAYFEFDIENELHLKQDYE- 307
            |||.||:|:.|.|.:     .||..:......|...:..:   :|....|.:.|   |:::...
 Frog   251 AHYLFGRPVEGHAFV-----LFGVQKDGRKTGIPESLARVQINEGEGRVELEGE---HIRKTLNT 307

  Fly   308 -------RQYLLDALVEEKSTGSVQNYSTVLTLHLNHYRVEAVKVPSYYIPGVPFEATARIARND 365
                   :.||..::|....|..|:.....:.:..:.|:|...|.|.|:.||:.|:....:...|
 Frog   308 TEEMLQYKLYLTVSVVTATGTDMVEAQLEEIYIVTSPYKVFFTKTPQYFKPGLSFDVMVFVTNPD 372

  Fly   366 GGQLRDFNPQITAYLTNVYGSSEMYNRTAYSLDASGEIKMKFTVPIGDRDEFH-SIIVDYQGVIS 429
            |...:..  .:......:.|.::          ..|..::....| .|.:|.| ::..:.:|
 Frog   373 GSPAKGI--PVVVQPGGISGVTQ----------TDGTTRLPMNTP-PDTNELHVTVRTEQEG--- 421

  Fly   430 EVGKIPSKH------------LHSKNYITAKVLNDRPTVNQEISV--VVRSFAP-----IKYFMY 475
                :|.:|            ..:.||:...:.....|:.:.:||  .:::..|     |::|.|
 Frog   422 ----LPPQHQANATMTATAYGSETGNYLHINIAESEITLGKGLSVNFFIKNSDPRFQEQIQHFTY 482

  Fly   476 QVVGRGDII-------LSRNVDVAPGTFHTIKFLASFAMMPRANLLVYTVIDGEFVYDEQVIQLE 533
            .|:.||.||       ||....||.....|..:|.||.::  |..:|.|....:.|.|...:.:.
 Frog   483 LVLSRGQIIKVDRQARLSDQPVVAMSLLITEDYLPSFRIV--AYYMVTTAKGRDIVSDSVWVDVV 545

  Fly   534 ENLLNAVQV------DAPIRAPPGQDIDIGISTKPYSYVGLMLVDQNANDLRSGHDLTHKRLMDA 592
            ::.:..::|      |..::..|. .:.:.:.....:.|||::||:....|.....||..::.|
 Frog   546 DSCMGTLEVTGLKDKDNAVQKLPA-TVQLKLRADHKANVGLVIVDKGVFVLNKKFKLTQSKIWD- 608

  Fly   593 LRSYELSDVNTPMGSPGKESGV-----ITMSNTDYFIE-------------KEAESNPALDREVS 639
              |.|.||:....||.....||     :|: :|.:.|.             |....:.|...|:.
 Frog   609 --SVEKSDIGCTPGSGVDSPGVFYDAGLTL-HTSFAITTIQRIKPYCKVPGKRKRRSTAAIIEIK 670

  Fly   640 TGPEEDKLTTVRKTDIG------PAHKIEVNT--LPPGKG---------RY-------------- 673
            .|...:....|::..:.      ..|..|..|  :..||.         :|
 Frog   671 AGKASEYKDKVKQCCLDGMQENLMGHSCERRTRYILDGKECVDAFLDCCKYYEKRREDERKSKDE 735

  Fly   674 ---AFSYTPKPFWHNPRVHVMRDPADTWLF--LNISASSDGRN----SIHRRIPSEMTSWVVSAF 729
               |.|.....:.....:.|..:..::|.:  :.:..:.|.:|    .|:..:...:|:|.|.|.
 Frog   736 DTLARSDEDSDYILESEIDVRSEFPESWRWDVVEMRENPDKQNISTKIINLNLKDSITTWEVLAV 800

  Fly   730 ALDPVNGLGLSPPNGKLEAYKEFYISTELPYSIKRDELIAIPFVVHNNRDSDLNVEVTF-YNSAL 793
            :|....||.::||: :::|.|:|:|..:||||:.|:|.:.|..||||...:.:...|.| ||
 Frog   801 SLSENKGLCVAPPH-EIKAMKDFFIDLKLPYSVVRNEQVEIRAVVHNYNSNRIKARVEFSYN--- 861

  Fly   794 DFDFPQLDPKATNQPKVELYRRRSLQVPGRSARSVSFIVTPKRVG--PLLVKAMAASSQAGDTVE 856
                |:....:|.:.|.    |:.:.|...|:..|.|::.|..:|  .:.|||........|.|.
 Frog   862 ----PEFCSLSTAKKKF----RQEVWVGAESSAVVPFVIVPLTIGQHDVEVKASVYKHFFSDGVR 918

  Fly   857 QNLLVEHPGAM------------ERINRGFLFELNSNAQNRRNVTIAVPRNAIPESTRIEVSAVG 909
            :.|.|...|.:            |...:..:.|:|..|....::   |||:.:.....::.|.:.
 Frog   919 KTLKVVPEGVLLTKTLSSVTLEPEVKGKDGVQEVNIGALTAEHI---VPRSDVDIKVILQGSPIS 980

  Fly   910 DLIGSLVG--NLDSLILLPTGCGEQTMVNFVPNLIVLRYL---GRLRQLTPEVELRATNNLAIGY 969
            .|:.|.:.  ||..||.:|||||||.|:....|:|..|||   .:.:::..:..:.|..|:|.||
 Frog   981 QLVESAIDGINLHPLIQIPTGCGEQNMMRMTTNVITTRYLDATAQWQRVGMDRRVAAIRNIAKGY 1045

  Fly   970 QRILYYRHENGAFSAFGLDIKRSSTWLTAYVARSLRQAAPFTQVDSNVLQKALTYLGSVQSANGG 1034
            |..|.||..:|.|:||  ..:.||||||||||:....:..:||::.|||..|:.:| ..:..||.
 Frog  1046 QEELVYRKPDGTFAAF--KDRPSSTWLTAYVAKVFAMSYEYTQIEDNVLCGAIKWL-EKKMQNGM 1107

  Fly  1035 FEERGDV--FERFG-------DDGISLTAFVTLALMENVDLYPE----YRNNINKALDFITRGLD 1086
            |.|.|.|  .|..|       :...:|||||.:|::|:.:|..:    ..::||:|.||:.....
 Frog  1108 FIESGPVIHMEMVGGNKAGAAEPDAALTAFVLIAMLESRELCTQQLTSLGDSINRATDFLRGKYS 1172

  Fly  1087 GSSNLHAMAIGTYVLSRANHNAKAAFLQRLDSM---ATNKDGLKWWNKTAPAGEQQSPWYNATRS 1148
            .....:::||.:|.|      |.|..||..:::   ||:|   ..||      |..|.:
 Frog  1173 QLRKPYSIAITSYAL------ALAGELQDTNTLMNAATDK---THWN------EPDSLF------ 1216

  Fly  1149 VNIEISAYAALALLENNLVGDALPVLNWLMDQRNPKGGFVASQDTVVGLQALLMF---AERFSSQ 1210
            :::|.::||.|.||:.........::.||.::|.....|.::|.|::..|||..:   ..|....
 Frog  1217 ISLEATSYALLTLLKMKQHDPTGAIVRWLNEKRYYGAVFNSTQATIIMFQALAQYQIDVPRIDDL 1281

  Fly  1211 GNNLQIGFHYGEGAETI-INVNAENSLALQTVELPNNLKNLSVSATGRGMAL---AQVSYTYNTN 1271
              :|.:..:..|..:.| :.::.||::..::.|...| |:..|.|.|:|.||   ..|.::..|.
 Frog  1282 --DLDVSLYLPEKQDPINVRIDLENAILARSTETKIN-KDFVVKAKGKGQALLTVVSVFHSLETE 1343

  Fly  1272 VTSAWPRFVLDPTVNRNSH-------ADYLHLSACASFVSVVGENEQRSNMAVMEVHLPSGFVVD 1329
            .......|.|...|....:       ...:.:..||.::     .:..:.|::|::.:.:||..|
 Frog  1344 KQMECNNFNLSVKVEEEKNMKLPDGVVAIVSVEVCARYL-----KDSDATMSIMDISMMTGFSPD 1403

  Fly  1330 RDTLPTL--ESSERIKKVETQNRNTK---VVIYFDYLDRRE-VCPTLHAYKTVKVTKHRPVAVVM 1388
            .|::..|  .:.:.|.|.|.....|:   :::|.|.:...| .|...:|::...|...:|.:|.:
 Frog  1404 TDSVNKLMKGADKYISKYEINKGATERGTIILYLDKISHTEPECVKFYAHQYFVVGLVQPASVTV 1468

  Fly  1389 YDYYDSARRARQFYRAPKSNIC--DICEHANCGDLCEKAEKR---ESKRPDDYTA 1438
            ||||....|..:||...:|:..  .:|:    ||:|..||:.   :.:..|:.||
 Frog  1469 YDYYTPENRCTKFYHTEESSALFGKLCQ----GDVCRCAEENCFLQKQIKDEVTA 1519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep3	NP_523507.2	A2M_N	124..215	CDD:280081	25/93 (27%)
		A2M_N_2	448..573	CDD:285005	32/144 (22%)
		A2M	697..787	CDD:278630	28/95 (29%)
		A2M_2	918..1203	CDD:239227	98/303 (32%)
		A2M_comp	967..1200	CDD:284982	76/248 (31%)
		A2M_recep	1313..1402	CDD:284981	24/94 (26%)
LOC100491968	XP_031755349.1	MG1	19..118	CDD:407662	20/109 (18%)
		A2M_N	124..219	CDD:396416	26/97 (27%)
		YfaS	<125..>336	CDD:225248	52/219 (24%)
		MG4	347..437	CDD:407661	18/109 (17%)
		A2M_N_2	445..595	CDD:400170	33/152 (22%)
		ANATO	673..732	CDD:237984	7/58 (12%)
		A2M	762..857	CDD:395153	28/95 (29%)
		complement_C3_C4_C5	991..1271	CDD:239226	98/303 (32%)
		A2M_recep	1387..1482	CDD:400149	24/94 (26%)
		NTR_complement_C3	1502..1651	CDD:239638	5/18 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177369at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010