Protein Alignment Tep3 and cpamd8

DIOPT Version :10

• Sequence 1: NP_523507.2
• Gene: Tep3 / 34045
• FlyBaseID: FBgn0041181
• Length: 1469
• Species: Drosophila melanogaster
• Sequence 2: XP_002934416.1
• Gene: cpamd8 / 100491045
• XenbaseID: XB-GENE-985023
• Length: 1827
• Species: Xenopus tropicalis
• Alignment Length: 1796
• Identity: 457/1796 - (25%)
• Similarity: 714/1796 - (39%)
• Gaps: 472/1796 - (26%)

  Fly    13 VLILVTACLLCQTS----AQGLYSIIAPNTLRPNSQFHVAVSLHNAPESATFKVGIL--GSSYTD 71
            :|.|....::|..|    .|| |.:.||:..|...:..|:|::.||......::.::  |.:...
 Frog     1 MLFLWIVWIICSFSRAEDRQG-YLVAAPSVFRSGVEEVVSVTIFNATTETKVQLQLVVKGETVAH 64

  Fly    72 FKTVELRPFSTQLLHFEIPA-LRTD-------RYRLTAEGLGGVQFTNETQLHFESKQHTVLVQT 128
            ...:.|...:.::|   :|: ||..       ...||.||.   .|.|.|.:..:||..:|.:||
 Frog    65 GHGIVLDKGTVKIL---VPSGLRGQANLKVWGNRHLTEEGF---SFHNSTTVTVDSKGSSVFIQT 123

  Fly   129 DKSIYKPGDLVHYRVLILDANLKPARGYGRVHVDIKDSGDNIIRSYKDIR-LTNSIYSNELRLSD 192
            ||.||||...|...:.::..:|:|..  .::...|.|...:.|..:.|:| :...:.:....|||
 Frog   124 DKPIYKPKQKVLINMFMVTPDLRPTS--EKIEAYILDPRGSRIIQWTDLRPICCGVVNMSFPLSD 186

  Fly   193 SPRFGTWSIVVDVSDQEHTQTFEILDHILPKFVVDIDTPKHAIYKDGKI-AATVRAHYAFGQPIV 256
            .|.||.|.|..:.....:.::|.:..::||||.:.|..|.: |...|.. ..||:|.|.||:|:.
 Frog   187 QPVFGEWLIFAETQGHTYNKSFSVQKYVLPKFELVISPPSY-IRDIGTCEKGTVKARYTFGKPVK 250

  Fly   257 GEATLSIYPTFFGSLQPFVNDLITRKVVPIDGNAYFEFDIENELHLKQDYERQYLLDALVEEKST 321
            |..|:::..|..|..:..:. |...|.:.|.|:|.|:...::.:.:  |:...:          .
 Frog   251 GLLTINMTVTGVGYYKHEIG-LQVLKTMEIYGSAVFDICAKDMMPV--DFPEHF----------R 302

  Fly   322 GSVQNYSTVLTLHLNHYRVEAVKVPSY----------------------YIPGVPFEATARIARN 364
            |:|..::||::       |:..|..::                      :.||:|::....:...
 Frog   303 GTVNIWATVIS-------VDGSKQVTFDDSTPVQKQLIDIKYTKDTKKQFKPGLPYQGKVEVTYP 360

  Fly   365 DGGQLRDFNPQITAYLT---NVYGSSEMYNRTAYSLDASGEIKMKFTVPIGDRDEFHSIIVDYQG 426
            ||........||.|.||   ||| :||:.:|...         ::|.:|        ||....|.
 Frog   361 DGSPADGVTVQIKAELTPKDNVY-TSELVSRNGL---------VEFQIP--------SIPTGAQY 407

  Fly   427 VISEV------GKIPSKHLHSKNYIT---------AKVLNDRP----TVNQEISVVVRSFAPIKY 472
            |..|.      || |:...:..||::         ..:|...|    .|.:|..:.::|..|...
 Frog   408 VWLETKVMAIDGK-PAGEQYLPNYLSISSWYSPSKCHLLIQPPEEPLLVGEEARIALKSTCPCNS 471

  Fly   473 FM-YQVVGRGDIILSRNVDVAPG-------------TFHT------------------------- 498
            .: |::|.||:|:||..   .||             ||..
 Frog   472 TLHYELVARGNIVLSGK---QPGKVTLKRSKRDAFVTFDKDTHESVTNTASTQIPSEDSTVWLTY 533

  Fly   499 IKFLASFAMMPRANLLVYTVID-GEFVYDEQVIQLEENLLNAVQVD-APIRAPPGQDIDIGISTK 561
            :.|..:..|.|.:.:|||.|.: ||.|.|...|.::....|.|.:. :...:.||..:||.:...
 Frog   534 VHFTVTHNMAPLSRILVYYVRENGEGVTDSAQIPIKPVFENQVSLTLSTNNSRPGDAVDINVKAA 598

  Fly   562 PYSYVGLMLVDQNANDLRSGHDLTHKRLMDALRSYELSDVN---------TPMGSPGK------- 610
            ..|.|.:..||::...||:|..||.:::...|..:::||..         ..|||..:
 Frog   599 KGSCVCVATVDKSVYLLRNGFQLTPEQIFQELSEFDVSDGTGKDEGHFWWPGMGSQRRRRSSLFP 663

  Fly   611 --------------ESGVITMSNTDYFIEKEAESNPALDREVSTGPEEDKLTTVRKTDIGPAHKI 661
                          |:|:|.|  ||..         :|:...|.|...|:..        ||.:.
 Frog   664 WHWDITKDARFAFTETGLIVM--TDIV---------SLNHRQSGGMYTDEAV--------PAFQP 709

  Fly   662 EVNTLPPGKGRYAFSYTPKPFWHNPRVHVMRDPADTWLFLNISASSDGRNSIHRRIPSEMTSWVV 726
            ...||      ...|||........|..........|...|:| ...|...:|..:|..:|:|:.
 Frog   710 HTGTL------VGSSYTRMATRTEKRKRTFFPETWVWHCFNVS-DVTGEQQLHVEVPDSITTWIT 767

  Fly   727 SAFALDPVNGLGLSPPNGKLEAYKEFYISTELPYSIKRDELIAIPFVVHNNR--DSDLNVEVTFY 789
            .|.|:....|||:: ....|:|:|.|:|...|||.:.|.|.:.||..|:|..  ..:::|::|..
 Frog   768 EAIAISSKKGLGVA-GQAHLKAFKPFFIDFTLPYHVIRGEQVKIPLTVYNYLPVGVEVHVKITIP 831

  Fly   790 NS-------------------------------------------ALDFD----FPQ-------- 799
            ..                                           ||.|.    ||:
 Frog   832 KGIKFVGYPGKQYLIRKLCVASGETKPTSAVFAFTDLGQANISARALAFAGMSCFPEGNTLRNKH 896

  Fly   800 -----LDPKATNQPKVELYRRRSLQV-PGRSARSVSFIV----------------------TPKR 836
                 |:.|.   |....:.||||.| |...||..::.|                      .|:|
 Frog   897 ADDAYLEKKV---PAGTDFVRRSLMVEPEGLAREYTYSVFFCPNEKIQISTPNKFEYQYVQKPQR 958

  Fly   837 VG--PLLVKA--------------MA-----------------ASSQAGDTV------------- 855
            :.  .|.|||              ||                 ::|:.||.|
 Frog   959 MTHFDLTVKAHNDAHIALSSGPHDMAEMIEIVIGGQQNSRTWISTSKMGDPVSSASTSSVLSWDE 1023

  Fly   856 ----------------------EQNLLVE-----HP-----------GAMERINRGFLFELNSNA 882
                                  ..:::||     .|           |:|....   ::......
 Frog  1024 FRAFWISWKNGVIQVGYGIYSSNDSVIVEWTVDRQPDVKFIGFSTGWGSMGEFK---IWRKEETD 1085

  Fly   883 QNRRNV-TIAVPRNAIPESTRIEVSAVGDLIGSLVGNLDSLILLPTGCGEQTMVNFVPNLIVLRY 946
            :|.... |:.||.|.||.|.|...|.:||::|..|.|||:|:.||.|||||.|::|.||:.||:|
 Frog  1086 ENHNEAFTLGVPHNVIPGSERATASIIGDVMGPTVSNLDNLLRLPFGCGEQNMIHFAPNVFVLKY 1150

  Fly   947 LGRLRQLTPEVELRATNNLAIGYQRILYYRHENGAFSAFGLDIKRSSTWLTAYVARSLRQAAPFT 1011
            |.:.|||.||||..|.:.|..||||.|.|:..:|::||||......|.||||:|.:|..|:..|.
 Frog  1151 LQKTRQLCPEVESEAVDYLVQGYQRQLTYKRLDGSYSAFGERDSSGSMWLTAFVLKSFAQSRGFI 1215

  Fly  1012 QVDSNVLQKALTYLGSVQSANGGFEERGDVFER---FGDDG-ISLTAFVTLALMENVDLYPEYRN 1072
            .:|...|..|..::...|:.:|.|...|.:..:   .|:.| |:|||:|..||:|......:.|.
 Frog  1216 FIDPGELSAAKDWIIQHQNKDGSFPAMGRILNKDIQGGNHGKIALTAYVAAALLETGVTSEDERI 1280

  Fly  1073 NINKALDFITRGLDGSSNLHAMAIGTYVLSRANHNAKAAFLQRLDSMATNKDGLKWWNKTAPAGE 1137
            .::||..|:...|....:.:..|:.:|.|:..........|::|::||...||...|:.|..|..
 Frog  1281 AVSKAKLFLESHLFTVDDPYTTALTSYALTLLRSTYAPVALRKLNAMAITHDGFTHWSLTGSAAT 1345

  Fly  1138 QQSPW--YN-----ATRSVNIEISAYAALALLENNLVGD---ALPVLNWLMDQRNPKGGFVASQD 1192
            ::..:  :|     :..|..:|::||   |||...|:||   ||||:.||..|||..|||.::||
 Frog  1346 EEDTFMGFNDGLSQSVISAEVEMTAY---ALLTYTLMGDVASALPVVKWLSQQRNSLGGFSSTQD 1407

  Fly  1193 TVVGLQALLMFAERFSSQGNNLQI-----GFHYGEGAETIINVNAENSLALQTVELPNNLKNLSV 1252
            |.|.||||..:|......|.||.|     ...|.|..|    ::..|...|||.::|:....|.|
 Frog  1408 TCVALQALAEYAILSYVGGVNLTISLASTNLDYQETFE----LHRLNKKILQTAKIPSIPTGLFV 1468

  Fly  1253 SATGRGMALAQVSYTYNTNVTSAWPRFVL-----DPTVNR-----------------------NS 1289
            ||.|.|..|.|:...||.....|.|.|.|     :|.::|                       .|
 Frog  1469 SAKGEGCCLMQIDVHYNVPDPVAKPAFQLLIYLKEPKLSRKRRHVVHQETPLRDRALPDDDDPGS 1533

  Fly  1290 HADY----LHLSACASFVSVVGENEQRSNMAVMEVHLPSGFVVDRDTLPTLESSERI--KKVETQ 1348
            |.|:    :.|.||..::     :...|||||:|:.|.|||..|.::|..|..:::|  |:.|..
 Frog  1534 HQDHQEYKITLEACTRWL-----HAGASNMAVLELALLSGFRADIESLEQLLLNKQIGLKRYEID 1593

  Fly  1349 NRNTKVVIYFDYLDRR-EVCPTLHAYKTVKVTKHRPVAVVMYDYYDSARRARQFYRAPKSN---- 1408
            .|  ||:.|||.:..: ..|..|.|::...|.|..||.|.:||||:....|.:||.|.:|:
 Frog  1594 GR--KVLFYFDEIPSQCLTCVKLQAFREYIVGKTAPVPVKIYDYYEPTFEATRFYNASESSPLSR 1656

  Fly  1409 -ICDICEHANCGDLCEKAEKRESKRPDDYTAIA--GHSSGS 1446
             :||       |..|.:.|    ...:.:||.:  |..||:
 Frog  1657 ELCD-------GTTCNEVE----SSANHWTAFSPNGPCSGT 1686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep3	NP_523507.2	YfaS	<128..1399	CDD:441940	411/1611 (26%)
		A2M_2	918..1203	CDD:239227	113/298 (38%)
cpamd8	XP_002934416.1	YfaS	<113..>877	CDD:441940	185/835 (22%)
		A2M_BRD	444..615	CDD:462235	39/173 (23%)
		A2M	737..828	CDD:459711	28/92 (30%)
		Methyltransf_FA	973..1075	CDD:463505	11/101 (11%)
		A2M_2	1119..1418	CDD:239227	114/301 (38%)
		A2M_recep	1554..1647	CDD:462226	36/94 (38%)
		KAZAL	1700..1744	CDD:197624