Protein Alignment Tep3 and cd109

DIOPT Version :9

• Sequence 1: NP_523507.2
• Gene: Tep3 / 34045
• FlyBaseID: FBgn0041181
• Length: 1469
• Species: Drosophila melanogaster
• Sequence 2: XP_031758448.1
• Gene: cd109 / 100486953
• XenbaseID: XB-GENE-954886
• Length: 1433
• Species: Xenopus tropicalis
• Alignment Length: 1506
• Identity: 387/1506 - (25%)
• Similarity: 659/1506 - (43%)
• Gaps: 206/1506 - (13%)

  Fly    15 ILVTACLLCQTSAQG------LYSIIAPNTLRPNSQFHVAVS-LHNAPESATFKVGILGSSYTDF 72
            :::...:||..|:..      ::.|.:|..:||.....:.:. |..:|.    .|.::.....|.
 Frog     7 LIIFPHILCFISSSAYAAAGPIFLITSPMDIRPGVNLTLGIEMLQESPP----LVKVVAQLQKDE 67

  Fly    73 KTV-------ELRPFSTQLLHFEIPALRTD-RYRLTAEGLG--GVQFTNETQLHFESKQHTVLVQ 127
            .|:       :...|.|.:|. ::|....: :|.|..:|..  .:.|.|:|.|.|:||..:|.::
 Frog    68 HTLLEGESFFKRGGFGTLVLP-QLPLNSVNGKYELNVKGYSEENLIFFNKTSLEFKSKGFSVFIE 131

  Fly   128 TDKSIYKPGDLVHYRVLILDANLKPARGYGRVHVDIKDSGDNIIRSYKDIRLTNSIYSNELRLSD 192
            |:...||||..|..|:|....::||.:  ..|.:.|.|...|:|..:.:..:...:.|..|.|||
 Frog   132 TNSVFYKPGQEVKIRILAFSFHMKPYK--STVDIYILDPQGNLIEQWLEEEMELGVVSQSLYLSD 194

  Fly   193 SPRFGTWSIVVDVSDQEHTQTFEILDHILPKFVVDIDTPKHAIYKDGKIAATVRAHYAFGQPIVG 257
            :|..|.|:|.|.:..|.|.|||.:::.:||:|.|.::|..:...|:..:..||.|.|.:|.|:.|
 Frog   195 NPPLGDWTIKVKLHQQLHYQTFTVMEQVLPRFEVLLNTTLYHSIKNPHLEGTVTAKYTYGMPVKG 259

  Fly   258 EATL-----SIYPTFFGSLQPFVNDLITRKVVPIDGNAYFEF-DIE-NELHLKQDYERQYL---- 311
            :.::     |||.......:.||          |:|.|.|.| ::| .||....||....:
 Frog   260 KLSVMLSHNSIYKKKTNITKDFV----------INGCARFSFSNVELKELMKNADYGSNKVTGPV 314

  Fly   312 -LDALVEEKSTGSVQNYSTVLTLHLNHYRVEAVKVPSYYIPGVPFEATARIARNDGGQL------ 369
             :|..|:|..||..||.:|.:.:....|.:|.:..|:...|.:.|....:|.|.||.:|
 Frog   315 DIDVNVKESLTGITQNVTTSVFVIDKEYNIEFLDHPTVLKPMLNFTIRLQIVRYDGRKLTAEERD 379

  Fly   370 ---------------RDFNPQITAYLTNVYGSSEMYNRTAYSLDASGEIKMKFTVPIGDRDEFHS 419
                           ||.:.::.|.......:.||...|.|::..:|.|.::  :|
 Frog   380 NEVAVTVTQTRRFNFRDNSVELNATENESEDNVEMIQLTRYTVPKNGIICIE--IP--------- 433

  Fly   420 IIVDYQGVISEVGKIPSKHLHSKN--------------YITAKVLNDRPTVNQEISVVVRSFAPI 470
            ::.|...:.     |.::.|.:||              ||..|..:....|....::.|....|:
 Frog   434 LLADIMHLY-----IKAEFLDAKNNLFINDLFSSLNGTYIQIKKADQDLKVGIPYTLSVDGSFPL 493

  Fly   471 KYFMYQVVGRGDIILS-----RNVDVAPGTFHTIKFLASFAMMPRANLLVYTVI-DGEFVYDEQV 529
            |...|.||.:|.|:..     :|:.:.|....|          |...|:||.|. ||....|...
 Frog   494 KDISYLVVSKGQIVAGGKGNPKNITLNPENTWT----------PEVCLIVYHVANDGTVTNDVTA 548

  Fly   530 IQLEENLLNAVQVD-APIRAPPGQDIDIGIS-TKPYSYVGLMLVDQNANDLRSGHDLTHKRLMDA 592
            :.::....|.|.:. ...:|.|...:.:.:: .:|.|.|.|.::|:....|....:::...::..
 Frog   549 VSVQPIFENKVYISWNTTQARPADMVSLNVNVAEPNSLVVLSVIDKRVKLLGDRQEISTANVLKE 613

  Fly   593 LRSYELSDV---NTPMGSPGKESGVITMSNTDYFIEKEAESNPALDREVSTGPEEDKLTTVRKTD 654
            |:||..|.:   ..|       |.|..|.|.....:...|.:...|....:|           .|
 Frog   614 LKSYSTSHIQHYTNP-------SEVFEMCNIGVMTDANIEVHDHFDILFESG-----------FD 660

  Fly   655 IGPAHKIEVNTLPPGKGRYAFSYTPKPFWHNPRVHVMRDPADTWLFLNISASSDGRNSIHRRIPS 719
            |.....:.||                  :.:||:..:.  .:||::.::...|....::..::|.
 Frog   661 IPVQGALPVN------------------FGSPRIRSLF--PETWIWKHLKTGSTTHMTLDLKVPD 705

  Fly   720 EMTSWVVSAFALDPVNGLGLSPPNGKLEAYKEFYISTELPYSIKRDELIAIPFVVHNNRDSDLNV 784
            .:|:|:.||:.:....|.|:..|..:|||::.|::|..||..:.|.|...:..:|.|....:..|
 Frog   706 VITTWITSAYVISENFGFGMLAPPEQLEAFQPFFLSLNLPSYVIRGEQFVLEVIVFNYLQKETEV 770

  Fly   785 EVTFYNS-ALDFDFPQLDPKATNQPKVELYRRRSLQVPGRSARSVSFIVTPKRVGPLLVKAMAAS 848
            .||...| |.:.....::...:.|         |:.||.:..:.|.|.:.|..:|.:.:...|.|
 Frog   771 SVTLEKSDAFEIQLAFVNASESQQ---------SVSVPSQEGKIVFFPIKPIHLGEIPITVKAIS 826

  Fly   849 SQAGDTVEQNLLVEHPGAMERINRGFLFELNSNAQNRRNVTI--AVPRNAIPESTRIEVSAVGDL 911
            :.|.|.|.|.|.|:..|..:..::..|.:|..|.....:.|:  ..|.:.:..|.:..::.|||.
 Frog   827 ALASDAVTQKLQVKAEGVQQSHSQTLLLDLMGNKPKSISQTLNFTFPPDVVSGSEKAFITVVGDH 891

  Fly   912 IGSLVGNLDSLILLPTGCGEQTMVNFVPNLIVLRYLGRLRQLTPEVELRATNNLAIGYQRILYYR 976
            :|..:.::.|||.:|.|||||.|:.|.||:.::.||.|.:||..:|..:..:.:..||||.|.|:
 Frog   892 LGLSIRSIKSLIQMPYGCGEQNMIRFAPNIFIMEYLSRTKQLNEDVAHKLISFIKNGYQRQLVYQ 956

  Fly   977 HENGAFSAFGLDIKRSSTWLTAYVARSLRQAAPFTQVDSNVLQKALTYLGSVQSANGGFEERGDV 1041
            .|:|:|||||......||||:|:|.:...:|.||..||..||...||:|...|..||.|.|.|.|
 Frog   957 REDGSFSAFGNKDPFGSTWLSAFVLQCFLKARPFILVDPVVLHNTLTWLLKHQRKNGEFWEPGTV 1021

  Fly  1042 FERFGDDG----ISLTAFVTLALMENVDLYPEYRNN--INKALDFITRGLDG-SSNLHAMAIGTY 1099
            .......|    |:|||::..||:|    ||..:|:  :..|.|::...:|. .|:.:.:::.||
 Frog  1022 IYSQIQGGHHSAITLTAYIMAALIE----YPGLKNSSQVAAATDYLESQMDEIISDNYTLSLVTY 1082

  Fly  1100 VLSRANHNAKAAFLQRLDSMATNKDGLKWWNKTAPAGEQQSPWYNATRSVNIEISAYAALALLEN 1164
            .||....:.....|..|:..|..:..|::|..:..:.:...       |.:|.|||||.|:.:..
 Frog  1083 ALSLVGRSKATEGLDLLNMRAEQEGQLRFWRSSISSCQHPC-------STDIVISAYALLSYVVQ 1140

  Fly  1165 NLVGDALPVLNWLMDQRNPKGGFVASQDTVVGLQALLMFAERFSSQGNNLQIGF-HYGEGAETII 1228
            |.:.:.:.|:.||..||:..|||.::|||::.|||:..||..::.....|.|.. .:...:....
 Frog  1141 NRIAEGMAVMKWLSQQRSHLGGFSSTQDTIIALQAMSSFASVYTINKQILAITVDSHPLNSTATF 1205

  Fly  1229 NVNAENSLALQTVELP-NNLKNLSVSATGRGMALAQVSYTYNTNVT--------SAWPRFVLDPT 1284
            .:::.|.:.|||.:|. ....||:|.|.|.|.|:.|....||...:        |:...|.|..|
 Frog  1206 QIDSNNRILLQTKQLAVQQQMNLTVHAEGTGFAILQFHTIYNLKNSVPGRYKSISSQDAFDLGIT 1270

  Fly  1285 V-NRNSHADYLHLSACASFVSVVGENEQRSNMAVMEVHLPSGFVVDRDTLPTLESSERIKKVETQ 1348
            | :...:.:.:.|:.|..  |:..:...::.|.:|:|.|.|||.:..:.:|   ....||||:
 Frog  1271 VLDNKDNLNVVSLNICTR--SIPRDGSTQTGMVLMQVDLLSGFSLVPEGIP---MKYPIKKVD-- 1328

  Fly  1349 NRNTKVVIYFDYLDRREVCPTLHAYKTVKVTKHRPVAVVMYDYYDSARRARQFYRAPKSNICDIC 1413
            ....|:.||.|.|::.|||..:.|.:..||...:...|.:.||||..:||.:.|.:........|
 Frog  1329 YNEGKINIYLDSLNQTEVCINIPATRDFKVGYTQEAFVYVIDYYDPGQRAIRSYNSEVMQQVSPC 1393

  Fly  1414 EHANCGDLCEK 1424
            ..  |.|.|.:
 Frog  1394 SF--CNDDCNQ 1402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep3	NP_523507.2	A2M_N	124..215	CDD:280081	30/90 (33%)
		A2M_N_2	448..573	CDD:285005	29/132 (22%)
		A2M	697..787	CDD:278630	23/89 (26%)
		A2M_2	918..1203	CDD:239227	102/291 (35%)
		A2M_comp	967..1200	CDD:284982	82/239 (34%)
		A2M_recep	1313..1402	CDD:284981	30/88 (34%)
cd109	XP_031758448.1	YfaS	57..1155	CDD:225248	305/1194 (26%)
		A2M	683..774	CDD:395153	24/90 (27%)
		A2M_2	895..1179	CDD:239227	102/294 (35%)
		A2M_recep	1298..1382	CDD:400149	30/88 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	72	1.000	Domainoid score	I9142
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H25183
Inparanoid	1	1.050	544	1.000	Inparanoid score	I1138
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177369at33208
OrthoFinder	1	1.000	-	-		FOG0002157
OrthoInspector	1	1.000	-	-		mtm14080
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2582
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.060