Protein Alignment Tep3 and LOC100006895

DIOPT Version :9

• Sequence 1: NP_523507.2
• Gene: Tep3 / 34045
• FlyBaseID: FBgn0041181
• Length: 1469
• Species: Drosophila melanogaster
• Sequence 2: XP_001923676.2
• Gene: LOC100006895 / 100006895
• -ID: -
• Length: 1449
• Species: Danio rerio
• Alignment Length: 1520
• Identity: 382/1520 - (25%)
• Similarity: 664/1520 - (43%)
• Gaps: 211/1520 - (13%)

  Fly    14 LILVTACLLCQT--SAQGLYSIIAPNTLRPNSQFHVAVSLHNAPESATFKVGILGSSYTDFKTVE 76
            |:|:...|:|..  :|:..:.::.|..:...|:..:..||.|..||....:.:...:.:   |:.
Zfish    19 LLLIFFLLVCVNGKTARPSFMVMFPIVIESGSEAKLCASLLNPNESLVMNIYLNDGNQS---TLL 80

  Fly    77 LRPFSTQLLH----FEIPALRTDRYRLTAEGLGGVQF--TNETQLHFESKQHTVLVQTDKSIYKP 135
            |:..:.|..|    |:.|..:.:..:.....|.|..|  |.|.::.|:|......:||||.||.|
Zfish    81 LQEKAEQEFHRCFNFKAPLAKAETVQKIKVELQGKSFEMTEERKVMFKSYDPLTFIQTDKPIYIP 145

  Fly   136 GDLVHYRVLILDANLKPA-RGYGRVHVDIKDSGDNIIRSYKDIRLTNSIYSNELRLSDSPRFGTW 199
            |..|::|::.||.|..|. :.|.  .|.::||.||.|..:.::..|..|......|:...|.||:
Zfish   146 GQTVNFRIVTLDKNFAPLDQQYS--SVVLEDSQDNRIGQWTNVSSTRWILQRSYELNPECREGTY 208

  Fly   200 SIVVDVSDQEHTQTFEILDHILPKFVVDIDTPKHAIYKDGKIAATVRAHYAFGQPIVGEATLSI- 263
            .:...:.:.|....|::..::||||.|.:..|......:.:::..|.|.|.:|||:.|::.:.:
Zfish   209 KLKTFIGEMEVLHYFKVKKYVLPKFEVTVKKPNKVSVDEEELSIEVCAKYTYGQPVPGKSWVKVC 273

  Fly   264 ---YPTFFGSLQPFVNDLITRKVVPI--DGNAYFEFDIENELH--LKQDYERQYLLDALVEEKST 321
               .|.|  ..:.| |.|.:.:...|  .|.|...|.:...|:  ||:..:....::|:|.|:.|
Zfish   274 RNSVPYF--HTKDF-NPLCSEETTEITKTGCAIHNFGVSVFLNSTLKERLKDSLHVEAVVTEEGT 335

  Fly   322 GSVQNYSTVLTLHLNHYRVEAVKVPSYYIPGVPFEATARIARNDGGQLRDFNPQITAYLTNVYGS 386
            ......|..:.|.....:|:.:.:|:.|..|...|          |:::.|:          :..
Zfish   336 EITMAKSESVPLTYEIGKVKVIDLPNTYEHGSVIE----------GKIKLFD----------FKD 380

  Fly   387 SEMYNRTAYSLDA---SGEIKMKFTVPIGDRDEFHSIIVDYQGV----ISEVGKI-PSKHLHSKN 443
            :.:.|:..|.|:.   |.::.:..|.   |.|...|..::...:    ||.:..: |....  :.
Zfish   381 APIPNKEVYLLEGENWSSKLLLNLTT---DSDGLASFSLNTSSLSKKDISLIANVYPDTRF--RQ 440

  Fly   444 YITAKVLNDRPTV---------------------NQEISVVVRSFAPIKYF-------------M 474
            |.|.....|:.||                     .|.|.......|.:||:             :
Zfish   441 YKTPYFSRDKKTVKLFQTATPYSPTFSKLIIENIEQPIKCGTEITATVKYYFVGETVEDFNTDIV 505

  Fly   475 YQVVGRGDII--------LSRNVDVAPGTFHTIKFLASFAMMPRANLLVYTVIDGE-FVYDEQVI 530
            |.|:.:|.|:        :..:..||.||. :.:......:.|...:|.|.|:..| .:...:.:
Zfish   506 YIVLSKGVIVHHGYEKVEVKSSNGVASGTM-SFELSVGADVAPVVRILAYCVLPSENIIAASKSL 569

  Fly   531 QLEENLLNAVQVD-APIRAPPGQDIDIGISTKPYSYVGLMLVDQNANDLRSGHDLTHKRLMDAL- 593
            .:|:...|.|.:. :|.:|.||:...:.:|.:|.|..||..|||:...|.||..|...::...|
Zfish   570 DIEKCFGNKVSLQFSPAKAVPGEKNTLQLSAQPGSLCGLSAVDQSVLILESGKRLDADKIFSLLP 634

  Fly   594 -----RSYELSDVNTPMGSPGKESGVIT--MSNTDYFIEKEAESNPALDREVSTGPEEDKLTTVR 651
                 ..|...| ..|.........|:|  :.|:...:..:..||.|:  .|........||..|
Zfish   635 FQYVYYPYSAED-EQPCLPVRPRRSVLTDNVYNSLKSVGLKMASNLAV--RVPECLSFRGLTYHR 696

  Fly   652 KTDIGPAHKIEVNTLPPGKGRYAF-SYTPKPFWHNPRVHVMRDPADTWLFLNISASSDGRNSIHR 715
            ..||...|.         .||... |......:.|..|.:.....:||::........|...:..
Zfish   697 FRDIVMYHT---------SGRVGLGSSIESSTFDNSAVTIRTIFPETWIWDLAEVGDSGSTEVPV 752

  Fly   716 RIPSEMTSWVVSAFALDPVNGLGLSPPNGKLEAYKEFYISTELPYSIKRDELIAIPFVVHNNRDS 780
            .:|..:|:|...||.|.. .||||:|| .:|..::.|::...|||||.|.|:..:...|.|....
Zfish   753 TVPDTITTWETEAFCLSS-TGLGLAPP-AQLTVFQPFFLELSLPYSIIRGEIFELKATVFNYLSK 815

  Fly   781 DLNVEVTFYNSALDFDFPQLDPKATNQPKVELYRRRSLQVPGRSARSVSFIVTPKRVGPLLVKAM 845
            .:.|:|:...|: |:..     ||::..:..    ..|...||  ::..:|:||..:|.:.| .:
Zfish   816 CIMVKVSPAPSS-DYTL-----KASSDDQYS----SCLCANGR--QTFKWILTPSVLGVVNV-TV 867

  Fly   846 AASSQAGDTVEQNLLVEHP--GAMERINRGFLF--------ELNS------NAQNRRNVTIAVPR 894
            :|.::|..||..|.:|..|  |.::.:.|..|.        |.||      ......||.:.||:
Zfish   868 SAEAEASQTVCDNEIVSVPERGRIDIVTRSLLVQAEGIEKTETNSWLLCPKGDSLSENVDLTVPK 932

  Fly   895 NAIPESTRIEVSAVGDLIGSLVGNLDSLILLPTGCGEQTMVNFVPNLIVLRYLGRLRQLTPEVEL 959
            :.|..|.:..||.:||::|..:.||..|:.:|.|||||.|....||:.:|:||...:|||..:..
Zfish   933 DVIEGSAKSSVSVIGDILGRALQNLHGLLRMPYGCGEQNMAVLSPNIYILQYLENTKQLTSAIRE 997

  Fly   960 RATNNLAIGYQRILYYRHENGAFSAFGLDIKRSSTWLTAYVARSLRQAAPFTQVDSNVLQKALTY 1024
            :|::.|..||||.|.|:|.:||:|.||..  ..:|||||:|.||..:|..:|.:|..::|.|..:
Zfish   998 KASSFLKSGYQRQLNYKHFDGAYSTFGYG--DGNTWLTAFVLRSFGKAQKYTFIDPQIIQSAKDW 1060

  Fly  1025 LGSVQSANGGFEERGDVFE---RFG-DDGISLTAFVTLALMENVDLYPEYRNNINKALDFITRGL 1085
            |.|.:.::|.|.::|.:|.   :.| .|.:::||::|.:|:|...  |.....:.|.|..:...:
Zfish  1061 LISRRDSDGCFIQQGRLFNNRMKGGVTDNVTMTAYITASLLELET--PVTDPVVTKGLSCLRSVI 1123

  Fly  1086 DGSSNLHAMAIGTYVLSRA-NHNAKAAFLQRLDSMATNKDGLKWWNKTAPAGEQQSPWYNATRSV 1149
            :...|.:..|:..|..|.| :.|.:.....:|:.:|.:...|..|:::|.|.:        :.|:
Zfish  1124 EDVKNTYTTALLAYTFSLARDTNTRQQLFSKLEDLAISDGPLVHWSQSASADD--------SASL 1180

  Fly  1150 NIEISAYAALALLENNL-----VGDALPVLNWLMDQRNPKGGFVASQDTVVGLQALLMFAER-FS 1208
            ::|||:|..||:|..:.     :|.|..:::||:.|:|..|||.::|||||.||||.::|.: ||
Zfish  1181 DVEISSYVLLAVLTADSLTTADLGFANRIVSWLVKQQNAYGGFSSTQDTVVALQALSLYATKVFS 1245

  Fly  1209 SQGNNLQIGFHYGEGAETIINVNAENSLALQTVELPNNLKNLSVSATGRGMALAQVSYTYNTNVT 1273
            |.|::.......|:...  .:||.:|.|..|..:|.|.....|:...|......|::..||....
Zfish  1246 SDGSSTVTVQSAGDSHH--FDVNQDNKLLYQEKQLANVPGKYSIEVKGSACVSVQMAQFYNIPTP 1308

  Fly  1274 SAWPRFVLDPTVN---RNSHADYLHLSACASFVSVVGENEQ-RSNMAVMEVHLPSGFVVDRDTLP 1334
            :......:|..|.   :.:....|.|:     |:|..:..| |:||.::::.|.|||..|...|.
Zfish  1309 TEAKTLSIDAEVEGDCKKTFGQNLMLN-----VTVTYDGPQNRTNMVIVDIKLLSGFTADTSMLK 1368

  Fly  1335 TLESS------------ERIKKVETQNRNTKVVIYF-DYLDRREVCPTLHAYKTVKVTKHRPVAV 1386
            |...|            |||     .:::..|::|. :.|....|...:...:.::|...:|..:
Zfish  1369 TQRQSFDSLDFFGHAPVERI-----DSKDDHVLVYLEEVLKEDPVNLQIGLNQIIQVKNLKPAVI 1428

  Fly  1387 VMYDYYDSARRARQFYRAPKSNICD 1411
            .:||||.::.::...|    |:.|:
Zfish  1429 KVYDYYQTSDQSEMEY----SSHCE 1449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep3	NP_523507.2	A2M_N	124..215	CDD:280081	28/91 (31%)
		A2M_N_2	448..573	CDD:285005	34/168 (20%)
		A2M	697..787	CDD:278630	27/89 (30%)
		A2M_2	918..1203	CDD:239227	99/294 (34%)
		A2M_comp	967..1200	CDD:284982	77/242 (32%)
		A2M_recep	1313..1402	CDD:284981	23/101 (23%)
LOC100006895	XP_001923676.2	A2M_N	134..225	CDD:280081	29/92 (32%)
		A2M_N_2	471..616	CDD:285005	33/145 (23%)
		A2M	734..822	CDD:278630	27/89 (30%)
		A2M_2	953..1239	CDD:239227	99/297 (33%)
		A2M_comp	1005..1241	CDD:284982	79/247 (32%)
		A2M_recep	1347..1444	CDD:284981	23/101 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177369at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010