DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tep2 and AI182371

DIOPT Version :9

Sequence 1:	NP_523506.1	Gene:	Tep2 / 34044	FlyBaseID:	FBgn0041182	Length:	1420	Species:	Drosophila melanogaster
Sequence 2:	XP_017174840.1	Gene:	AI182371 / 98870	MGIID:	2138853	Length:	366	Species:	Mus musculus

Alignment Length:	224	Identity:	53/224 - (23%)
Similarity:	90/224 - (40%)	Gaps:	25/224 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 YSVVGPGTLRSNSKYNVVVSVHKADGPSQIKVSLNG-PSYNETKQIELPPMSTQN-------VEF 79
            |.:..|...|..:..||.|..|.........||:.. |..|.........:|.:|       :..
Mouse    42 YIISTPIVFRVGAPENVTVQAHGHTEAFDTTVSVKSYPDENVRYSFSTVNLSPENKFQNTAILTI 106

  Fly    80 EVPKLATGNYNLSAEGVSGVVFKNSTKLNYAD---KKPSVFVQTDKATYKPADLVQFRILFLDEN 141
            :..:|:.|..:.|...:. ||.|:..||....   ...|:||||||:.|.|...|:.|:..::::
Mouse   107 QAKQLSEGQNSFSNSYLE-VVSKHFAKLEIVPIIYDNDSLFVQTDKSVYTPQQPVKVRVYSVNDD 170

  Fly   142 TRPAKIEKPISVIIIDGAQNRIKQLSDVKLTKGVFS-GELQLSEQPVLGTWKISVSV--DGDNRE 203
            ..||..|..::.|..:|:|  :..:....|| |:.| .:.::...|..|.|.:....  |.....
Mouse   171 LEPATRETVLTFIDPEGSQ--VDTIEGNNLT-GIASFPDFEIPSNPKHGRWTVKAKYREDASKTG 232

  Fly   204 TKSFEVDKY-------VLPKFEVIVDTPK 225
            |..|||.:|       ::|..::..:..|
Mouse   233 TTYFEVKEYDKTYRISIMPTIDLQPEVEK 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tep2	NP_523506.1	A2M_N	115..209	CDD:280081	27/96 (28%)
		A2M_N_2	445..576	CDD:285005
		A2M	694..782	CDD:278630
		A2M_2	909..1198	CDD:239227
		A2M_comp	961..1199	CDD:284982
		A2M_recep	1308..1398	CDD:284981
AI182371	XP_017174840.1	MG1	42..138	CDD:375333	21/96 (22%)
		A2M_N	145..238	CDD:376626	26/95 (27%)
		ANATO	279..347	CDD:237984
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840001
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2373
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740