Protein Alignment Tep2 and LOC100492134

DIOPT Version :9

• Sequence 1: NP_523506.1
• Gene: Tep2 / 34044
• FlyBaseID: FBgn0041182
• Length: 1420
• Species: Drosophila melanogaster
• Sequence 2: XP_031755348.1
• Gene: LOC100492134 / 100492134
• -ID: -
• Length: 1656
• Species: Xenopus tropicalis
• Alignment Length: 1651
• Identity: 400/1651 - (24%)
• Similarity: 667/1651 - (40%)
• Gaps: 396/1651 - (23%)

  Fly    14 ALLVNATGIY----SVVGPGTLRSNSKYNVVVSV--HKA---------DGP------SQIKVSLN 57
            :||:...|.|    :::.|..||..::..:||..  |.:         |.|      :..|||||
 Frog     9 SLLLLVAGSYAQQCTLITPSLLRVETEETIVVDAQGHNSAFEANILIQDFPQKKLSLASAKVSLN 73

  Fly    58 GPS-YNETKQIELP----PMSTQNVEFEVPKLATGNYNLSAEGVSGVVFKNSTKLNYADKKPSVF 117
            ..: :..:..:::|    |..|:|.:|....:::|:..|          :.:..|.|:  ...:|
 Frog    74 NNNGFLGSATVKIPSDQLPKETRNNQFVYVSVSSGSCTL----------EKAVMLQYS--SGYIF 126

  Fly   118 VQTDKATYKPADLVQFRILFLDENTRPAKIEKPISVIII--DG---AQNRIKQLSDVKLTKGVFS 177
            :||||..|.|...|...:..::....|  |.||:.:..:  ||   .:...:..|    ..|:||
 Frog   127 IQTDKTIYTPGSKVMCWVFSMNYKMNP--ITKPMVIKFVNPDGIIVMRETFRPTS----KSGIFS 185

  Fly   178 GELQLSEQPVLGTWKISVSVDGDNRE--TKSFEVDKYVLPKFEVIVDTPKA-VVIADKVIKATIR 239
            ....|.:....|.|.:....:...::  |.:|||.:||||..|||:....: ...:.:.....|.
 Frog   186 KTYALPKLVSPGIWTVLAKYEDTPQQDYTTNFEVKEYVLPTIEVILKPENSFYYTSSETFSVDIE 250

  Fly   240 AKYTYGKPVKGKATVSMERSYGYFGDLNANGNK---QEKTIDV---DGKGHVEFDIIHWAQRGQY 298
            |.|.:|:||:|.|.|       .|| :..:|.:   .|....|   :|:|..|...:|..   :|
 Frog   251 AHYLFGRPVEGHAFV-------LFG-VQKDGTRTGIPESLARVQINEGEGRAELKGVHLQ---KY 304

  Fly   299 LPP-----IKLFAVVTEELTGNKQNATATVVLHQQRYSI----EPY-----ERPEHFEANKSFIY 349
            |..     .||:      :|.:...||.|.::..|...|    .||     :.|::|:...::..
 Frog   305 LNAAEMLNYKLY------MTVSVATATGTDMVEAQLEEIYIVSSPYRILFSKSPQYFKPGLTYDL 363

  Fly   350 QVVVKNVDGSPVTNSAKNVKIGFDKSYSYFHEPSPKTRINFEAPVNENGIA--TFN-----VRLP 407
            .|:|.|.||||    |..:.:..|..             ||......:|.|  |.|     ..:|
 Frog   364 TVLVTNPDGSP----ANRIPVVVDPG-------------NFRGETQADGTARLTLNPEAGKAAMP 411

  Fly   408 DS------------------DSRYYRIFASFD--------GSENTIGSISKFEPTPMSREPLKIQ 446
            .|                  .::.|....||:        |||..:|...          .:...
 Frog   412 ISVKTDKKGVQPRHQATATMSAKAYSPAYSFNNYLHISVPGSELKLGGTL----------AVYFY 466

  Fly   447 VNTKKPRLGEQVSFDVVSIEDLPYFVYTIVARGNVILSDYVDVPDGQKTYTVKFTPTFSMVPKAT 511
            :.|..|.:.||:.          :|.|.:::||.:|.....:....:....:..:.|...:|...
 Frog   467 IKTDSPEVAEQIR----------HFTYLVMSRGRIIKVGRQERSPNKPVVAMSLSVTEDYLPSFR 521

  Fly   512 IYVYYVV----NNDLQFEEKTIDFEKEFSNSIDVSA---PTNA--KPSEEVKLRIKTDADSFVGL 567
            |..||:|    ..|:..:...:|.......:::|:.   ..||  .||..|:|::..|..:.|||
 Frog   522 IVAYYMVTTTKGGDIVSDSVWVDVVDTCMGTLEVTGYKDKDNAVQYPSASVQLKLTADHKANVGL 586

  Fly   568 LGVDQSVLLLKSGNDLSQDDIFNSLNIYQTSTPWMNGYGRYPGQTSGLVTLTNANYPYNTGPLVM 632
            :.||:.|.||.....|:|..:::|:....|        |..||  ||   ..:|...|:.| |.:
 Frog   587 VIVDKGVFLLNKKYKLTQSKVWDSVEKSDT--------GCTPG--SG---ANSAGVFYDAG-LAL 637

  Fly   633 SYVF--------EGSRHPWITRPR--------YRVGIRGDSGDRISFLSQSLNDRNLKEILLKQT 681
            ...|        |.....|..|.:        .:.|...:..|:   ..|...| .::|.|:..:
 Frog   638 QTSFSITTDQRIEPQCKDWAPRKQRSFVAVMEIKTGKASEYKDK---AKQCCLD-GMQENLMGHS 698

  Fly   682 PQRTT----------------------------------------------------IRKEFPET 694
            .:|.|                                                    ||.:|||:
 Frog   699 CERRTRYILDGKECVDAFLDCCKYYEKRREDERKSKDEDTLEIYEEDSGYMMNNEIEIRSDFPES 763

  Fly   695 WFFENVGEEEFT------------LTKKIPDTITSWVVTGFSLNPTSGIALTKNPSKIRVFQPFF 747
            |::.   ||:.|            |..::.|:||:|.|...||:...|:.:.. |.:|:..:.|.
 Frog   764 WYWR---EEQMTGAADKDKISTKILNVQLKDSITTWEVLAVSLSENKGLCVAP-PHEIKAMKDFS 824

  Fly   748 VSTNLPYSVKRGEVIAIPVVIFNYLDKTLDADVVMDNSDQEYEFTEATNEVLEKAIDEVRRVKRV 812
            :...||.||.|.|.:.|..|:.||....:.   |:.......||..     |.|...:.|  :.|
 Frog   825 IDLKLPSSVVRNEQVEIRAVVHNYNSHKIK---VLVKFGYNKEFCS-----LSKPKQKFR--QEV 879

  Fly   813 TIPANSGKSVSFMIRPKNVGFTTLKITAT--SALAGDAIHQKLKVEPEGVTLFEN---------- 865
            .:.|.|...|.|:|.|..:|...:::||.  .....|.:.:.|.|.||||.|.:.
 Frog   880 WVGAESSAVVPFIIVPLELGQHVVEVTAVVYRQFVSDGVRKTLNVVPEGVLLSKTLNSVILEPEV 944

  Fly   866 ------RAVFINLKDQPEMSQSLDADIPNEVV----PQSEFIEFSVVGDLLGPTLQNLDNLVRMP 920
                  :.|.|.....|.:....|.||  :|:    |.|:.:|.::.|       ..|.:|::.|
 Frog   945 KGRGGVQEVTIKALSAPNIVPKSDIDI--KVILQGTPISQLVESAIDG-------SKLRHLIQKP 1000

  Fly   921 YGCGEQNMVNFVPNILVLKYLEVTGR-KLPSVESKARKF--LEIGYQRELTYKHDDGSYSAFGKS 982
            .|.|||||:....|::..:||:.|.: :...|:.:....  ::.||||||.|:..|||::||  .
 Frog  1001 VGSGEQNMMRMTTNVITTRYLDATAQWQRVGVDRRETAIGNIKDGYQRELAYRKPDGSFAAF--Q 1063

  Fly   983 DASGSTWLTAYVMRSFHQAGTYTDIDPKVITAGLDFLVS-KQKESGEFPEVGKLFD--------- 1037
            ....||||||||.:.|..:..||:||..|:...:.:|.: :|...|.|.|.|.:..
 Frog  1064 IRPSSTWLTAYVAKVFAMSYEYTEIDDYVLCGAIKWLFNERQMPDGMFVENGPVLQMEMGGGNKA 1128

  Fly  1038 NANQNPLALTSFVLLAFFENHELIPKYQS----AIKKAVRYVAEEADKTDDQYSLAIAAVALQLA 1098
            .|.:...|||:|||:|..|:.|:..:..|    ||.:|..::..:..:....||:||.:.||.||
 Frog  1129 GAAEPDAALTAFVLIAMLESREICTQRLSNLGDAINRATNFLRGKYSQLRKPYSVAITSYALALA 1193

  Fly  1099 KHPQSEKVIAKLESVARKENDRMWWSKATESTGEDGRVFHWKPRSN---DVEITSYVLLALLEKD 1160
            ...|....:.               :.||:.:       |||...:   .:|.|||.||.||:..
 Frog  1194 GKLQDTNTLL---------------NAATDKS-------HWKEPDSLFITLEATSYALLTLLKMK 1236

  Fly  1161 PAEKALPIIKWLISQRNSNGGFSSTQDTVIGLQALTKFAYKTGSGSG-TMDIEFSSAGESKNTIK 1224
            .......|::||..||.....|.|||.|:|..|||.::.....:.|. .||:..... |.|:.:.
 Frog  1237 QHNPTSAIVRWLNEQRYYGAVFDSTQATIILYQALAQYQTDVPNVSDLNMDVSVFFP-EKKDPVS 1300

  Fly  1225 VNPEN--SLVLQTHDLPKSTRKVDFT--AKGTGSAMVQLSYRYNLAEKEKK---PSFKVTPTVKD 1282
            ::.:|  :|.|::.::   |...||.  |||.|.|::.:...|:....||:   .:|.::.||.:
 Frog  1301 IHIDNKSALRLRSEEI---TVNQDFVVKAKGKGQALLTVVSVYHALTTEKQMECKNFDLSVTVNE 1362

  Fly  1283 TPNQLL--------IVDVCAEYVPLEDADKDKDSNMAVMEIALPSGFVGDSTSLGKI-QAVDR-V 1337
            ..|..|        .::|||.|:      |..|:.|::::|::.:||..|:.||..: :.||: :
 Frog  1363 EKNLKLPDGVVAAVSIEVCARYL------KKSDATMSIVDISMMTGFSPDTNSLNNLMKGVDKYI 1421

  Fly  1338 KRVETK---NSDSTVVVYFDSLTPGDVRCLPLEASKAHAVAKQKPASVSLYDYYDTERKATEYYQ 1399
            .:.|..   |...|:::|.|.::..:..|:...|.:...|...:||||::||||..|.:.|::|.
 Frog  1422 SKYEINKGANERGTLILYLDKISHTEPECVKFYAHQYFVVGLVQPASVTVYDYYTPENRCTKFYH 1486

  Fly  1400 VKSS------LC--DICEGADCGEGC 1417
            |..|      :|  |:|..|:  |.|
 Frog  1487 VNESSALYGKICQGDVCRCAE--ENC 1510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep2	NP_523506.1	A2M_N	115..209	CDD:280081	23/100 (23%)
		A2M_N_2	445..576	CDD:285005	31/139 (22%)
		A2M	694..782	CDD:278630	26/99 (26%)
		A2M_2	909..1198	CDD:239227	96/308 (31%)
		A2M_comp	961..1199	CDD:284982	82/254 (32%)
		A2M_recep	1308..1398	CDD:284981	27/94 (29%)
LOC100492134	XP_031755348.1	MG1	19..118	CDD:407662	20/108 (19%)
		A2M_N	124..219	CDD:396416	23/100 (23%)
		MG3	221..304	CDD:407663	25/93 (27%)
		MG4	346..436	CDD:407661	19/106 (18%)
		A2M_N_2	446..596	CDD:400170	35/169 (21%)
		ANATO	674..733	CDD:237984	7/62 (11%)
		A2M	763..858	CDD:395153	27/101 (27%)
		complement_C3_C4_C5	989..1274	CDD:239226	97/315 (31%)
		A2M_recep	1390..1485	CDD:400149	27/94 (29%)
		NTR_complement_C3	1505..1654	CDD:239638	3/8 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177369at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010