Protein Alignment Tep2 and LOC100487726

DIOPT Version :10

• Sequence 1: NP_523506.1
• Gene: Tep2 / 34044
• FlyBaseID: FBgn0041182
• Length: 1420
• Species: Drosophila melanogaster
• Sequence 2: XP_031758487.1
• Gene: LOC100487726 / 100487726
• XenbaseID: XB-GENE-29078871
• Length: 1413
• Species: Xenopus tropicalis
• Alignment Length: 1469
• Identity: 414/1469 - (28%)
• Similarity: 692/1469 - (47%)
• Gaps: 255/1469 - (17%)

  Fly    50 SQIKVSL----NGPSYNETKQI---------ELPPMSTQNVEFEVPKLATGNYNLSAEGVSG--V 99
            |:|.|:.    ||.|...:.::         .:||:|..:        ::.:|.:...|.:|  :
 Frog    54 SEITVTAEIWDNGISLANSSKVFQKDILGLLSIPPLSVIS--------SSASYLIRVYGTAGNEL 110

  Fly   100 VFKNSTKLNYADKKPSVFVQTDKATYKPADLVQFRILFLDENTRPAKIEKPISVIIIDGAQNRIK 164
            :|.|:..:....|..|:.::|||:.|||...|:.||:.:..:.||.|  ..::|:|.|...|.||
 Frog   111 LFSNNYTMQLETKNVSLLIETDKSAYKPGQTVKIRIISIRRDLRPYK--GLVNVVIRDPKSNIIK 173

  Fly   165 QLSDVKLTKGVFSGELQLSEQPVLGTWKISVSVD-GDNRETKSFEVDKYVLPKFEVIVDTPKAVV 228
            |....|...||.:.|..||...:.|||::....| .:|.|  ...|..:..|||:|.:.||...|
 Frog   174 QWLQRKPELGVITEEFLLSVNAMAGTWRVHAETDMTENIE--EISVIHFEHPKFDVTIKTPSFYV 236

  Fly   229 -IADKVIKATIRAKYTYGKPVKGKATVSMERSYGYFGDLN-ANGNKQEKTIDVDGKGHVEFDIIH 291
             ...:.:..|:.|.||||:||||.|||.:...|    |:. |||.|  ||.::.|.....|....
 Frog   237 DPKQQNLIGTVIANYTYGRPVKGNATVLITSLY----DIQAANGIK--KTYEMSGSADFTFTYAE 295

  Fly   292 WAQRGQYLP---PIKLFAVVTEELTGNKQNATATVVLHQQRYSIEPYERPEHFEANKSFIYQVVV 353
            .::    ||   .:.:.|||.|||||...:.::.|......|.:....:|.......:||.::.:
 Frog   296 LSR----LPSGLTLNITAVVKEELTGIAISKSSYVKKVDSEYELVIVSQPPVLIPGINFITKIQL 356

  Fly   354 KNVDGSPVTNSAKNVKIGFDKSYSYF---------HEPSPKTRINF----EAPVNENGIATFNVR 405
            :..|...:|...:...|....:.|:.         :.|:..|.:|:    :..:.|:||.:..:.
 Frog   357 QRKDRLHLTQGERENNISVKVTQSFMPWLVETEGVNTPTGATNLNYVETLQYNIPESGIISVELP 421

  Fly   406 LPDS------DSRYYRIFASFDGSENTIGSISKFEPTPMSREPLKIQVNTKKPRLGEQVSFDVVS 464
            |.:|      ::.|..|...:. ....:|..|.          .:||:.....::|......|.:
 Frog   422 LQNSVLLIIIEAVYQNITQKWQ-MHRDLGISSS----------AQIQLPDSPAQVGTPFDVRVKT 475

  Fly   465 IEDLPYFVYTIVARGNVILSDYVDVPDGQKTYTVKF--TPTFSMVPKATIYVYYVVNNDLQFE-- 525
            ..::....|.|:|||.::.:        :||.:..|  ||.:|..|.|.:.||::..|:..||
 Frog   476 TPEIQNLYYVIMARGIIVAA--------EKTNSTTFTLTPEYSWAPSAVLMVYFLNFNNNSFEII 532

  Fly   526 --EKTIDFEKEFSNSIDVS-APTNAKPSEEVKLRIK-TDADSFVGLLGVDQSVLLLKSGNDLSQ- 585
              .:|||.:..|.|.:.:| :.|...|||.|:|.:. |:|.|.|||..||.|..||.:||.|.:
 Frog   533 QASRTIDIKGMFENKVSLSWSVTKTAPSENVRLNVDITEAGSLVGLRVVDISDKLLSNGNHLKEK 597

  Fly   586 ---------DDIFNSLNIYQTSTPWMNGYGRYPGQTSGLVTLTNANYPYNTGPLVMSYVFEGSRH 641
                     .|..|||                   |.|:::                  ::|
 Frog   598 VEAEMKSYTKDFVNSL-------------------TDGIIS------------------YDG--- 622

  Fly   642 PWITRPRYRVGIRGDSGDRISFLSQSLNDRNLKEILLKQ-TPQRTTIRKE----------FPETW 695
                                              |||:: .|:...||:|          |||||
 Frog   623 ----------------------------------ILLEEFIPELFIIREEIEPPANVPIVFPETW 653

  Fly   696 FF--ENVGEE-EFTLTKKIPDTITSWVVTGFSLNPTSGIALTKNPSKIRVFQPFFVSTNLPYSVK 757
            .:  .|:... ..:|...:|:.:|||..:.|.::...|:.|.:...:::.|||||::.|.||:|.
 Frog   654 IWLETNISSGIRTSLPVTVPNAVTSWTASAFVISDVLGLGLIEESVELQAFQPFFITLNAPYAVT 718

  Fly   758 RGEVIAIPVVIFNYLDKTLDADVVMDNSDQEYEFTEATNEVLEKAIDE-----VRRVKRVTIPAN 817
            |||...:.|:::|.|::.|..:|.::           ||...:..|.|     :..::.|:|.:.
 Frog   719 RGEQFILRVLLYNCLEENLQVNVSLE-----------TNNAFDIIIPENDNGAIPWLRNVSIRSK 772

  Fly   818 SGKSVSFMIRPKNVGFTTLKITATSALAGDAIHQKLKVEPEGVTLFENRAVFINLKDQPEMSQSL 882
            ..:.:.|.:.||.:|...:.:.|.|..|.|...||:.|:.|||..|..:.:.:.:.....:||.|
 Frog   773 ESEIILFPVSPKQLGVNFITVRAMSRTASDIATQKILVKAEGVQNFYTQNLILEVNGTGSVSQQL 837

  Fly   883 DADIPNEVVPQSEFIEFSVVGDLLGPTLQNLDNLVRMPYGCGEQNMVNFVPNILVLKYLEVTGRK 947
            ....|..||..||....|||||.|||:::.|::|:|||||||||||:||.|.|.||:||..|.::
 Frog   838 SFTFPTNVVGGSEQASVSVVGDFLGPSIKGLESLIRMPYGCGEQNMINFAPIIYVLQYLTSTSQQ 902

  Fly   948 LPSVESKARKFLEIGYQRELTYKHDDGSYSAFGKSDASGSTWLTAYVMRSFHQAGTYTDIDPKVI 1012
            ...:..:|..|:|.|||.||.|:..|.|:||||..|:|||:||:|:|:|.|.||.|:.:|.|:::
 Frog   903 TEDIRRRAISFMEQGYQSELNYRRGDDSFSAFGDRDSSGSSWLSAFVVRCFLQARTFINISPEIL 967

  Fly  1013 TAGLDFLVSKQKE-SGEFPEVGKLFDNANQ----NPLALTSFVLLAFFENHELIPKYQSAIKKAV 1072
            ...:::|:.:|.. :|:|.|.|.:|::..|    .|:.||::||.:..||.:....|.|.:.|||
 Frog   968 NRTVEWLIQQQDPVNGKFLEPGHVFNSRLQGGLNGPITLTAYVLTSLLENSQYSIHYASRVGKAV 1032

  Fly  1073 RYVAEEAD-KTDDQYSLAIAAVALQLAKHPQSEKVIAKLESVARKENDRMWWSKATESTGEDGRV 1136
            :|:.:|.: .....|:|::.|.||.:|...::...:.:|.|.....:.:::||..|      |..
 Frog  1033 QYLEKEFEGGISSNYTLSVVAYALSVANSTKASAALTQLNSRTSNNDGQIYWSSPT------GAS 1091

  Fly  1137 FHWKPRSNDVEITSYVLLALLEKDPAEKALPIIKWLISQRNSNGGFSSTQDTVIGLQALTKF-AY 1200
            .:|:|.|.|:|..:|.||:..:::...:.:||:.||:.|||:.||:||||||::.|.||.:| |.
 Frog  1092 NYWQPPSADIETAAYALLSHCQQNRIAEGVPIMNWLVQQRNNLGGYSSTQDTIVALWALAQFMAV 1156

  Fly  1201 KTGSGSGTMDIEFSSAGE-SKNTIKVNPENSLVLQTHDLPKSTRKV-DFTAKGTGSAMVQLSYRY 1263
            .......::.:..:..|. :..:.::..:|.|.:|...:..|...| :.:|.|.|.|:.||:..|
 Frog  1157 APSLKETSLTVSVTGPGPFAPKSFQITNDNLLAVQIQQIDISYPIVLNVSAVGRGIAIFQLNGIY 1221

  Fly  1264 N---LAEKEK----KPSFKVTPTVKDTPN--QLLIVDVCAEYVPLEDADKDKDSNMAVMEIALPS 1319
            |   |..:::    |.:|.::.|..|..|  :||.||:|:.|...|:     :..|.::::...|
 Frog  1222 NKRVLPRRKQNTPNKEAFALSVTTTDVGNNTELLYVDICSSYQGTEN-----EVGMVLLDVGFLS 1281

  Fly  1320 GF------VGDSTSLGKIQAVDRVKRVETKNSDSTVVVYFDSLTPGDVRCLPLEASKAHAVAKQK 1378
            ||      :.:|..|         |.||||  ...|.:||||:|...| |:.:...:...||..:
 Frog  1282 GFKLHPRGIPESGLL---------KMVETK--ADRVYLYFDSMTTNSV-CVTVPVVRTALVAGSR 1334

  Fly  1379 PASVSLYDYYDTERKATEYYQVKS----SLCDICEGADC 1413
            ...|::.|||:....||..|..::    |:||.| |::|
 Frog  1335 EGIVTITDYYNPTNSATRTYNSETMKNLSICDFC-GSNC 1372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep2	NP_523506.1	YfaS	<72..1395	CDD:441940	397/1410 (28%)
		A2M_2	909..1198	CDD:239227	112/294 (38%)
LOC100487726	XP_031758487.1	YfaS	<131..1214	CDD:441940	346/1206 (29%)
		A2M_2	864..1153	CDD:239227	112/294 (38%)
		A2M_recep	1268..1355	CDD:462226	27/103 (26%)