Protein Alignment Tep2 and LOC100487580

DIOPT Version :10

• Sequence 1: NP_523506.1
• Gene: Tep2 / 34044
• FlyBaseID: FBgn0041182
• Length: 1420
• Species: Drosophila melanogaster
• Sequence 2: XP_031761620.1
• Gene: LOC100487580 / 100487580
• XenbaseID: XB-GENE-29078819
• Length: 1472
• Species: Xenopus tropicalis
• Alignment Length: 1542
• Identity: 402/1542 - (26%)
• Similarity: 670/1542 - (43%)
• Gaps: 255/1542 - (16%)

  Fly     7 TGIILQYALL--VNATGI---------YSVVGPGTLRSNSKYNVVVSVHKADGPSQIKVSLN--G 58
            ||.:.|..||  |...|:         |::..|..|:|.......:::...|.|.|:.|:|.  |
 Frog    22 TGTMFQQRLLACVCLLGLISGAISKPRYALSVPAVLKSGENSTACINILDNDSPLQLNVNLEFYG 86

  Fly    59 PSY---NET---------KQIELPPMSTQNVEFEVPKLATGNYNLSAEGVSGVVFKNSTKLNYAD 111
            .:|   :||         |:..:|.:| ..|...:..:|||..:...|..|.|:.| ...:|
 Frog    87 ANYSIFSETVQEKTIFKCKEFTVPAVS-MTVPVFITMVATGPRDTIMERRSAVIGK-MENIN--- 146

  Fly   112 KKPSVFVQTDKATYKPADLVQFRILFLDENTRPAKIEKPISVIIIDGAQNRIKQLSDVKLTKGVF 176
                 |||.||:.||....||.|::.|:...||.: |...::.|:|...:||.|..:....:|:.
 Frog   147 -----FVQLDKSIYKAGQKVQCRLISLNPLLRPVQ-ETYTAIYILDPLGSRIFQWLNKTSRQGLV 205

  Fly   177 SGELQLSEQPVLGTWKISVSVDGDNRETKSFEVDKYVLPKFEVIVDTPKAVVIADKVIKATIRAK 241
            :.|..|.....|||:.|..........::.|||.:|.||::.|.|..|..:.|.|:.|...:.||
 Frog   206 ALEYLLLSDATLGTYNIVAERISGPAVSQPFEVAEYALPRYSVTVAAPNTISIQDQNITFQVNAK 270

  Fly   242 YTYGKPVKGKATVSMERSYG-YFGDLNAN----GNKQEKTIDVDGKGHVEF--DI-IHWAQRGQY 298
            ||||:.|.||.:..:.|.|. |:..::.|    |..|....|||..|...:  |: :...:||..
 Frog   271 YTYGQGVPGKLSGRLCRKYNYYYPGMSCNRKPEGLCQNIAGDVDPSGTFNYTADLALFQLERGGL 335

  Fly   299 LPPIKLFAVVTEELTG---------NKQNATATVVLHQQRYSIEPYERPEHFEANKSFIYQVVVK 354
            ...:.....:||..||         :..|..|.|....|  :|:||.:|       ...|:|.:.
 Frog   336 DMVLSYQITLTENGTGVQVTESGSVSISNLIARVSFDYQ--AIQPYYKP-------GIPYRVAMT 391

  Fly   355 --NVDGSPVTNSA----------------KNVKIGFDKSYSYFHEPSPKTRI-----------NF 390
              |..|:|::|..                :|.|:.::...|.:.:|....:.           |:
 Frog   392 LVNAAGNPLSNETIELRVSGNNVQNLTTDRNGKVRYELDVSGYEQPQLDLQAIYKNAETCYDPNW 456

  Fly   391 EAPVNENGIAT-----------FNVRLPDSD---SRYYRIFASFDGSENTIGSIS--KFEPTPMS 439
            ..|:..|.:.|           ..:..|..:   ...|.|.|.:..|...:|:::  .|....||
 Frog   457 VMPIYSNDVYTVTRFFSRTGSYVEISAPQQELSCGNSYTIKAHYSLSPKALGNVTNVSFYYLVMS 521

  Fly   440 REPLKIQVNTKKPRLGEQVSFDVVSIEDLPYFVYTIVARGNVILSDYVDVPDGQKTYTVKFTPTF 504
            :        ||..:.||.    :|::...|       .||               |:::..|.:.
 Frog   522 K--------TKIVKSGEH----LVALNSRP-------QRG---------------TFSLNLTVSQ 552

  Fly   505 SMVPKATIYVYYVVNNDLQFEEKTIDFEKEFSNSIDVS-APTNAKPSEEVKLRIKTDADSFVGLL 568
            .:.|...:.||.::.:::...:..::.||.|.:.:.:| :.:...|...|.|.::.|..|..|||
 Frog   553 ELAPGFDVIVYSMLQSEVIAHKIHLNTEKCFEHQVSLSFSASQGTPGSNVNLTLRADPRSLCGLL 617

  Fly   569 GVDQSVLLLKSGNDLSQDDIFNSLNIYQTSTPWMNGY--GRYPGQTSGLVTLTNANYPYNTGPLV 631
            .:|.|::||..|..|:.:.::|:|....     :|||  |.|..:.:....:.:.|...:.|.:.
 Frog   618 AIDSSLILLGPGTQLTAERVYNALQYLS-----LNGYSVGEYNVEPAAPPCIDSENRVLDDGLVY 677

  Fly   632 MSYVFEGSRHPW-----------ITRPRYRVGIRGDSGDRISFLSQSLNDRNLKEILLKQTPQR- 684
            ....|.|..:.:           .....|:..:.|..|..:.|...     |:...|....|..
 Frog   678 QPVQFPGQGNTYNEFKSAGLHFATNSSIYKPELCGFYGYTLGFFHS-----NMATPLSATLPVSV 737

  Fly   685 -------TTIRKEFPETWFFE-----NVGEEEFTLTKKIPDTITSWVVTGFSLNPTSGIALTKNP 737
                   :|:||.|||.|.|:     :.|.....|  |.|||||.|..:.|.|:...|:.:||.|
 Frog   738 SVPGEPISTVRKSFPEVWNFDIVAVGDTGSASPAL--KAPDTITQWQASMFCLSEGKGLGVTKYP 800

  Fly   738 SKIRVFQPFFVSTNLPYSVKRGEVIAIPVVIFNYLDKTLDADVVMDNSDQEYEFTEATNEVLEKA 802
            |......||||..::|:|..|||::.:...:.|||::.:...|.:..| ::|      ..||::.
 Frog   801 SNFTSSLPFFVEVSVPFSFTRGEMLLLRAFVSNYLNQCIKVRVTLQPS-KDY------TAVLQEG 858

  Fly   803 IDEVRRVKRVTIPANSGKSVSFMIRPKNVGFTTLKITATSALAG---------------DAIHQK 852
            ..:      :.:......|.|:.:...::|..:..:||.:...|               |.:.:.
 Frog   859 TQD------MCVCPKGRASYSWNVTANSLGVISFNVTAQTTFIGATCGGPPNTTQPPRSDTVIKT 917

  Fly   853 LKVEPEGVTLFENRAVFINLKDQPEMSQSLDADIPNEVVPQSEFIEFS------VVGDLLGPTLQ 911
            :.||.||:   |....:.||    ...:..:|.||..:.|.:..::.|      |:||.||..:.
 Frog   918 VIVEAEGI---EKEVTYSNL----VCVEGNNAQIPFSITPPANMVKGSAKASVTVIGDPLGHAVN 975

  Fly   912 NLDNLVRMPYGCGEQNMVNFVPNILVLKYLEVTGRKLPSVESKARKFLEIGYQRELTYKHDDGSY 976
            |.|:|::||.||||||:|..:|...||.||..:|:....::.||.:::..||.|:|.:|..||::
 Frog   976 NPDSLIQMPTGCGEQNLVKLLPIPAVLAYLNCSGQLTKEIQDKAVQYMATGYVRQLGFKRYDGTF 1040

  Fly   977 SAFGKSDASGSTWLTAYVMRSFHQAGTYTDIDPKVITAGLDFLVSKQK-ESGEFPEVGKLFDN-- 1038
            ||||:.|..||:||||..:.:|.:...||.:||.||..||..|...|. :||.|...|.||::
 Frog  1041 SAFGQRDPEGSSWLTALSLYTFQKIKQYTLVDPTVINQGLVALEKSQDLQSGCFKVSGTLFNSEL 1105

  Fly  1039 --ANQNPLALTSFVLLAFFENHELIPKYQSAIKKAVRYVAEEADKTDDQYSLAIAAVALQLAKHP 1101
              ..:|.::.|::|:....|.:  .|..|:.::..:..:...:.:....|:||:...|..|:.:.
 Frog  1106 KGGAENEISFTAYVVAILMETN--YPGAQTLLRNGLGCLDAASRREQTLYNLALLFYAFSLSGNE 1168

  Fly  1102 QSEK-VIAKLESVARKENDRMWWSKATESTGEDGRVFHWKPRSNDVEITSYVLLALLEKDPA--- 1162
            :... .:|||:.:|..||..:.|.:..:...|....|:..|.|.|:|||.||||. ..|.||
 Frog  1169 ERRNATLAKLKKLAIHENGGIHWEQTDKPIAEKYPFFYAPPPSADIEITGYVLLG-FTKGPAPSQ 1232

  Fly  1163 -EKA--LPIIKWLISQRNSNGGFSSTQDTVIGLQALTKFA---YKTGSGSGTMDIEFSSAGESKN 1221
             ||:  ..|..||:.|:||.|||.||.|||:.||||.:::   ||.|:   |..:..|.|.:...
 Frog  1233 EEKSYMTQIAVWLVRQQNSQGGFRSTADTVVALQALAEYSCLVYKKGA---TNRVTVSLARQVIA 1294

  Fly  1222 TIKVNPENSLVLQTHDLPKSTRKVDFTAKGTGSAMVQLSYRYNLAEKEKKPSFKVTPTVKDTPNQ 1286
            |..|.|.|.|::|...||.......|...|.|..::|.:.:||:....|..:|.::.......
 Frog  1295 TFNVQPSNRLLVQRRMLPSQQGNYSFGVSGNGCCLIQSTVKYNVPVVRKNSTFSLSVNTSSGS-- 1357

  Fly  1287 LLIVDVCAEYVP----LEDADKDKDSNMAVMEIALPSGFVGDSTSLGKIQAVDRVKRVETKNSDS 1347
              .::..|..:|    |....:...|||||:::.|.||:.....||  :|...:|.:||..|:.
 Frog  1358 --CINGAAFIIPINLTLSYNGRKNQSNMAVVDMKLLSGYSVQYQSL--LQLRQQVPKVEQINNH- 1417

  Fly  1348 TVVVYFDSLTPGDVRCLPLEASKAHAVAKQKPASVSLYDYYDTERKA 1394
             :::|..|:....: .||:.....:.|...:|.|:.:|||||.:..|
 Frog  1418 -LIIYLSSVQREPI-SLPVSLEMGNRVQNFQPQSIYVYDYYDQDENA 1462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep2	NP_523506.1	YfaS	<72..1395	CDD:441940	380/1452 (26%)
		A2M_2	909..1198	CDD:239227	108/300 (36%)
LOC100487580	XP_031761620.1	YfaS	<147..1326	CDD:441940	333/1260 (26%)
		ISOPREN_C2_like	973..1271	CDD:415487	108/300 (36%)
		A2M_recep	1379..1465	CDD:462226	28/89 (31%)