Protein Alignment Tep2 and LOC100487426

DIOPT Version :10

• Sequence 1: NP_523506.1
• Gene: Tep2 / 34044
• FlyBaseID: FBgn0041182
• Length: 1420
• Species: Drosophila melanogaster
• Sequence 2: XP_017945276.2
• Gene: LOC100487426 / 100487426
• XenbaseID: XB-GENE-29078767
• Length: 1464
• Species: Xenopus tropicalis
• Alignment Length: 1533
• Identity: 406/1533 - (26%)
• Similarity: 649/1533 - (42%)
• Gaps: 246/1533 - (16%)

  Fly     6 LTGIIL------QYALLVNATGIYSVVGPGTLRSNSKYNVVVSVHKADGPSQIKV---------- 54
            |.|||.      |||..:          |..|:|.......::.........:||
 Frog    16 LLGIIAGGAAKQQYAFSI----------PALLKSGESATACINFIDLTESMSLKVIVEVSGVNTT 70

  Fly    55 ----SLNGPSYNETKQIELPPMSTQNVEFEVPKLATGNYNLSAEGVSGVVFKNSTKLNYADKKPS 115
                .|.|....:.|..::|.:.|.:..| :...|||..:...|....|:          ||..:
 Frog    71 IFTDKLTGKEVFKCKSFKVPDVKTASPVF-ITMEATGKTSTIVERRPVVI----------DKMEN 124

  Fly   116 V-FVQTDKATYKPADLVQFRILFLDENTRPAKIEKPISVIIIDGAQNRIKQLSDVKLTKGVFSGE 179
            : .:|.||..||.|..|..|:|.|..|.||.. |....:.:.|...:|::|..||...:||.:.|
 Frog   125 INLIQLDKPIYKRAQKVMARVLSLSPNLRPVP-ETYTLIYLTDPYGSRMRQWEDVTSVRGVAAFE 188

  Fly   180 LQLSEQPVLGTWKISVSVDGDNRETKSFEVDKYVLPKFEVIVDTPKAVVIADKVIKATIRAKYTY 244
            ..|.....|||:.|:.........::.|||.:||||:..:.::.||.|.|.|..:..:..|||||
 Frog   189 FGLLNDASLGTYTITAQKKSGGSISQVFEVAEYVLPRLSMTLEAPKTVSIQDHTVPISANAKYTY 253

  Fly   245 GKPVKGKATVSMERSY-GYFGDLNANGNKQ------EKTIDVDGKGHVEFDIIHW-AQRGQYLPP 301
            |:.|.||.:..:.|.| .|:...|.|.|.:      ...:..||......|:..: ..||.:...
 Frog   254 GQGVPGKISGKLCRQYSSYYPGNNCNRNPEGICSHITGQMSSDGNFSQNIDLSQFQLDRGGFSMN 318

  Fly   302 IKLFAVVTEELTG----NKQNATATVVLHQQRYSIE---PYERPEHFEANKSFIYQVVVKNVDGS 359
            :.|...||||.||    ..::.:.|..:.|..:..|   |:.:|     ...:...:.:.|..|.
 Frog   319 LNLDVTVTEEGTGVQVKESRSISVTSQVAQVTFDNEVMRPFYKP-----GIPYPVSMTLVNSIGK 378

  Fly   360 PVT----------NSAKNV------KIGFDKSYSYFHEPSPKTRINFEAPVNENGIATFNVRLPD 408
            |:.          ||.:|:      |..::...|.:.:.....:.|::   |....|..|..:|.
 Frog   379 PIKNEKIELLVAGNSVQNLTTDQSGKATYEIDTSKYEQTQLDIQANYK---NTETCADSNWVVPS 440

  Fly   409 SDSRYYRI--FASFDGS---------ENTIGSISKFEPTPMSREPLKIQVNTKKPRLGEQVSFDV 462
            ..:.||..  |.|..||         |.:.|.:          :.:|:..:..|..|||:|  :.
 Frog   441 YSNAYYSAGRFYSRTGSYVQMNAPKQELSCGKV----------QSMKVHYSLSKEGLGEKV--NT 493

  Fly   463 VSIEDLPYFVYTIVARGNVILSDYVDVPDGQK-TYTVKFTPTFSMVPKATIYVYYVVNNDLQFEE 526
            ||...|......||..|    |..|||...:: :::.....:..:.|.|.:.||.::::::..|.
 Frog   494 VSFYHLVMSKVKIVDSG----SHSVDVSKSRRGSFSFDIPVSSELAPGANVVVYSLLDSEVIEET 554

  Fly   527 KTIDFEKEFSNSIDVS-APTNAKPSEEVKLRIKTDADSFVGLLGVDQSVLLLKSGNDLSQDDIFN 590
            ..::.|..|.|.:.:| :.....|...|||::|.|..|..||..||.|.|||.....|:.:.|:|
 Frog   555 IHLNVENCFENQVSLSFSEAEGMPGSNVKLKLKADPKSMCGLKIVDSSTLLLSQNGQLTPEVIYN 619

  Fly   591 SLNIYQTSTPWMNGY--GRY-----------PGQ---TSGL----VTLTNANYPYNTGPLV-MSY 634
            :|....     :|||  |:|           |.|   .:||    |:.....|.||....: :.:
 Frog   620 ALRYLS-----LNGYYVGQYNVEPPAPPCIDPNQRVMMNGLFYQPVSFPGEGYTYNDFKSIGLIF 679

  Fly   635 VFEGSRH-PWIT--------RPRYRVGIRG-DSGDRISFLSQSLNDRNLKEILLKQTPQRTTIRK 689
            |...|.| |.:.        ||.:....|. ...:|.:|::..:....:..  .|..|.. |:||
 Frog   680 VTNVSLHKPEVCGQNVWGGGRPVFLNAARPMGMAERFTFMADGMGAAGVSS--AKAAPVE-TVRK 741

  Fly   690 EFPETWFF-----ENVGEEEFTLTKKIPDTITSWVVTGFSLNPTSGIALTKNPSKIRVFQPFFVS 749
            .|||.|.|     :|.|  ..|:|:|:|||||.|..:.|.::...||.|||.||.:..:.|||:.
 Frog   742 FFPEVWKFDFATVDNTG--ALTVTEKVPDTITQWQGSMFCMSEEKGIGLTKYPSNLTSYLPFFLE 804

  Fly   750 TNLPYSVKRGEVIAIPVVIFNYLDKTLDADVVMDNSDQEYEFTEATNEVLEKAIDEVRRVKRVTI 814
            .:||||..|||.:.:..|:.|||||.:..:..|..| .:|..|....|            :...:
 Frog   805 VSLPYSFVRGETLVLTAVVANYLDKYVKVEATMKPS-ADYTATLQQGE------------QNTCL 856

  Fly   815 PANSGKSVSFMIRPKNVGFTTLKITATSALAG---------------DAIHQKLKVEPEGVTLFE 864
            ......|.|:.:..|::|..|..:||.:...|               |.:.|...||.||:   |
 Frog   857 SPRQRASFSWNVNAKSLGAITFTMTAKTTHIGASCKGPSDNSQSPRSDTVIQSTIVEAEGI---E 918

  Fly   865 NRAVFINLKDQPEMSQSLDADIPNEVVPQSEFI------EFSVVGDLLGPTLQNLDNLVRMPYGC 923
            ....:.||    ...:...:.||..:.|....:      ..:|:|||||..:.|.|:|::||.||
 Frog   919 KEITYSNL----VCVEGTKSVIPINITPPPNMVADSAQGSVTVIGDLLGHAVNNPDSLIQMPTGC 979

  Fly   924 GEQNMVNFVPNILVLKYLEVTGRKLPSVESKARKFLEIGYQRELTYKHDDGSYSAFGKSDASGST 988
            ||||:|..:|...||.||..:|:....::.||.:|::.||.|:|.||..||::||||:||..||:
 Frog   980 GEQNLVKLMPIPAVLAYLNCSGQLTKEMQDKAVQFMQTGYIRQLGYKRWDGTFSAFGQSDHEGSS 1044

  Fly   989 WLTAYVMRSFHQAGTYTDIDPKVITAGLDFLVSKQ-KESGEFPEVGKLFDN----ANQNPLALTS 1048
            ||||.:..:|.....||.:||.|....|..|...| .::|.|...|.||.:    ...|.::.|.
 Frog  1045 WLTALIFHTFELIKPYTLVDPTVQNQALLALQRMQDPKTGCFKATGTLFHSGLKGGADNEISFTG 1109

  Fly  1049 FVLLAFFENHELIPKYQSAIKKAVRYVAEEADKTDDQYSLAIAAVALQLAKHPQSEK-VIAKLES 1112
            :|....:...  .|..|:.:..|...:.|.:.:....|:|.:...|..::.:.:... ::|:|:|
 Frog  1110 YVAAMLWNTP--YPAAQTLLHGAFSCLDEASKREQSLYNLVLMFYAFAVSGNMEKRNYILAQLKS 1172

  Fly  1113 VARKENDRMWWSKATESTGEDGRVFHWKPRSNDVEITSYVLLALL-----EKDPAEKALPIIKWL 1172
            .|..:.....|.:..:...|....|.....|.:.|||.|.||.:.     .:|.......|..|.
 Frog  1173 KAIHKVGTTHWERPDKPKEETSPFFSAPSPSAETEITGYALLGMTYGPAPSQDDKSYMAQIALWF 1237

  Fly  1173 ISQRNSNGGFSSTQDTVIGLQALTKFA---YKTGSGSGTMDIEFSSAGESKNTIKVNPENSLVLQ 1234
            ..|:||.||:.||.|||:.|:||.:::   ||.|:   |..::.:|.........|.|.|.|::|
 Frog  1238 AQQQNSQGGYRSTADTVVALRALARYSCLIYKPGA---TNQVKVTSGNTVIANFNVQPNNRLLVQ 1299

  Fly  1235 THDLPKSTRKVDFTAKGTGSAMVQLSYRYNLAEKEKKPSFKVTPTVKDT--------PNQLLIVD 1291
            ...|||......|..:|.|..:||.|.|||:            |.:|..        .::...|:
 Frog  1300 RQPLPKVPGNYGFEVEGKGCCLVQCSVRYNV------------PVIKGVSAFSLSVQSDRKSCVN 1352

  Fly  1292 VCAEYVPLEDA----DKDKDSNMAVMEIALPSGFVGDSTSLGKIQAVDRVKRVETKNSDSTVVVY 1352
            ..|..:|:..:    .....|||||:...|.||:..:..||.:::  ..|.:||  ..|:.:|:|
 Frog  1353 GVAYTIPIAMSVSYHGNRNQSNMAVIMAKLLSGYTVEYQSLQQLR--QNVSKVE--QMDNRLVIY 1413

  Fly  1353 FDSLTPGDVRCLPLEASKAHAVAKQKPASVSLYDYYDT 1390
            .:|::...: .|.:....::.|...:|..|.::|||:|
 Frog  1414 LESVSSKPI-TLSVTLEMSNRVQNFQPQFVYVFDYYET 1450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep2	NP_523506.1	YfaS	<72..1395	CDD:441940	390/1447 (27%)
		A2M_2	909..1198	CDD:239227	95/299 (32%)
LOC100487426	XP_017945276.2	YfaS	<131..1318	CDD:441940	343/1246 (28%)
		ISOPREN_C2_like	965..1263	CDD:415487	95/299 (32%)
		A2M_recep	1371..1457	CDD:462226	25/85 (29%)