Protein Alignment CG7025 and AGBL2

DIOPT Version :9

• Sequence 1: NP_609133.2
• Gene: CG7025 / 34042
• FlyBaseID: FBgn0031930
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_079059.2
• Gene: AGBL2 / 79841
• HGNCID: 26296
• Length: 902
• Species: Homo sapiens
• Alignment Length: 514
• Identity: 100/514 - (19%)
• Similarity: 164/514 - (31%)
• Gaps: 206/514 - (40%)

  Fly     8 IVLALVVLAQGASFGQDERL----RYDNYSVYK-VKFETQAQRSILR-KLAEDREN----FRLWH 62
            ||..|.|..||.   :|..|    |:::.::.| |:.:|......|| .|..::..    ||:.:
Human   250 IVKELAVTLQGP---EDNTLLFESRFESGNLQKAVRVDTYEYELTLRTDLYTNKHTQWFYFRVQN 311

  Fly    63 EAKDELHL-----MLSPGAFGELETEIQKTNVTAELFISNVQELIDSEEAANLKASRDGTFGWTK 122
            ..||..:.     :|.|                ..|:...::.|:.|:..||.:     ..||.:
Human   312 TRKDATYRFTIVNLLKP----------------KSLYTVGMKPLLYSQLDANTR-----NIGWRR 355

  Fly   123 YNSLAEIY--------------AWL-------DDILAA--YP---TITESFIVG----------- 150
            ..:..:.|              .|.       |....|  ||   |..:.:::.
Human   356 EGNEIKYYKNNTDDGQQPFYCLTWTIQFPYDQDTCFFAHFYPYTYTDLQCYLLSVANNPIQSQFC 420

  Fly   151 ------QSYEGRTIRGIKISYKSNNP-------GVLIESNIHAREWITSATATWLINEFL----- 197
                  :|..|.|:..:.|:..|..|       .|::.:.:|..|    :..:|::..||
Human   421 KLQTLCRSLAGNTVYLLTITNPSQTPQEAAAKKAVVLSARVHPGE----SNGSWVMKGFLDFILS 481

  Fly   198 TSTD-ELVRDLAENHDWYIVPVLNVDGFVYTHEKDRMWRKTRQPSEISSCIGADPNRNYDSHWME 261
            .|.| :|:||:   ..:.::|:||.||.:..:.:             .|..|.|.||:|.:...|
Human   482 NSPDAQLLRDI---FVFKVLPMLNPDGVIVGNYR-------------CSLAGRDLNRHYKTILKE 530

  Fly   262 NEGASSNPCAEDYGGPKPFSEPEIQAMSEFVISIKDKINVLL--AFHSYSQ---LLLSPYGHTKE 321
                 |.||              |......:..:.::..|||  .||.:|:   :.|  ||....
Human   531 -----SFPC--------------IWYTRNMIKRLLEEREVLLYCDFHGHSRKNNIFL--YGCNNN 574

  Fly   322 E---------FP----PNFDDMMEVAKAYGDAVESLPYGTVYRYGSAAGILYPASGATIDWAYNE 373
            .         ||    .|..|.... .:....|:....||               |..:.|   .
Human   575 NRKYWLHERVFPLMLCKNAPDKFSF-HSCNFKVQKCKEGT---------------GRVVMW---R 620

  Fly   374 QGVEISYTIEF----------RDTGRYGFILPPVHIIPNAEEALIGIAALLEKCKDLGY 422
            .|:..|||:|.          |||          |.             .:|..|.|||
Human   621 MGILNSYTMESTFGGSTLGNKRDT----------HF-------------TIEDLKSLGY 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416	14/77 (18%)
		M14_CP_A-B_like	123..416	CDD:199844	67/376 (18%)
AGBL2	NP_079059.2	GVQW	105..>120	CDD:290611
		M14_AGBL2-3_like	407..666	CDD:133117	65/333 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	746..770
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	796..879

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900