DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7025 and Agbl3

DIOPT Version :9

Sequence 1:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_001276585.1	Gene:	Agbl3 / 76223	MGIID:	1923473	Length:	1006	Species:	Mus musculus

Alignment Length:	367	Identity:	70/367 - (19%)
Similarity:	121/367 - (32%)	Gaps:	141/367 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 DNYSVYKVKFETQAQRSILRKLAEDRENFRLWHEAKDELHLMLSPGAFGELETE---IQKTNVTA 91
            ||..|::.:||:...:.:::             .|..|..|.:.|..|....|:   .|.||..|
Mouse   171 DNTLVFEARFESGNLQKVVK-------------VADHEYELTVRPDLFTNKHTQWYYFQVTNTQA 222

  Fly    92 E---------------LFISNVQELIDSEEAA-------------------NLKASRDG----TF 118
            |               |:...::.|..||:.|                   ||  .:||    :.
Mouse   223 EIVYRFTIVNFTKPASLYNRGMKPLFYSEKEAKTHNIGWQRIGDQIKYYKNNL--GQDGRHFFSL 285

  Fly   119 GWT------------------KYNSLAEIYAWLDD---------ILAAYPTITESFIVGQSYEGR 156
            .||                  .|::|.|..:.::.         |.....|:..:.:    |...
Mouse   286 TWTFQFPHSQDTCYFAHCYPYTYSNLQEYLSGINSDPVRSKFCKIRVLCHTLARNMV----YVLT 346

  Fly   157 TIRGIKISYKSNNPGVLIESNIHAREWITSATATWLINEFL------TSTDELVRDLAENHDWYI 215
            ....:|.| .|....|::.:.:|..|    ..::|::..||      :|...|:||   ...:.:
Mouse   347 ITTPLKTS-DSKRKAVILTARVHPGE----TNSSWIMKGFLDYILGDSSDARLLRD---TFIFKV 403

  Fly   216 VPVLNVDGFVYTHEKDRMWRKTRQPSEISSCIGADPNRNYDSHWMENEGASSNPCAEDYGGPKPF 280
            ||:||.||.:..:.:             .|..|.|.||||.|...|
Mouse   404 VPMLNPDGVIVGNYR-------------CSLAGRDLNRNYTSLLKE------------------- 436

  Fly   281 SEPEIQAMSEFVISIKDKINVLLAFHSYSQLLLSPYGHTKEE 322
            |.|.:......:..:.:|..|:|    |..|    :||::::
Mouse   437 SFPSVWYTRNMINRLMEKREVIL----YCDL----HGHSRKQ 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416	15/84 (18%)
CG7025	NP_609133.2	M14_CP_A-B_like	123..416	CDD:199844	43/215 (20%)
Agbl3	NP_001276585.1	M14_AGBL2-3_like	315..576	CDD:133117	40/208 (19%)
Agbl3	NP_001276585.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	790..810
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900