DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7025 and cpa1

DIOPT Version :9

Sequence 1:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_001107681.1	Gene:	cpa1 / 497006	XenbaseID:	XB-GENE-960032	Length:	420	Species:	Xenopus tropicalis

Alignment Length:	433	Identity:	166/433 - (38%)
Similarity:	242/433 - (55%)	Gaps:	41/433 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VLALVVLAQGASFGQDERLRYDNYS---VYKVKFETQAQRSILRKLAEDRENFRL--WH------ 62
            :|||:.|...||       ..:|:|   |.::....:||.:::|.| ||.|..:|  |.
Frog     4 ILALLALVVAAS-------SLENFSGQQVLRIFPSDEAQVNLVRAL-EDEEYLQLDFWTSPSRVL 60

  Fly    63 ---EAKDELHLMLSPGAFGELETEIQKTNVTAELFISNVQELIDSE--EAANLKASRDG----TF 118
               :.:..||.:.|      ::..::..::...:.|.:||.|:|.|  :....:||.||    :|
Frog    61 LPIDIRVPLHHLQS------VKVYLESNSIQYSIMIHDVQNLLDEEQRDMRRNRASEDGRSTNSF 119

  Fly   119 GWTKYNSLAEIYAWLDDILAAYPTITESFIVGQSYEGRTIRGIKISYKSNNPGVLIESNIHAREW 183
            .:..|::..||.|::|::::..|.:.....:|.|||||.:..:|.|...|.|...|::.||:|||
Frog   120 NYAAYHTFDEINAFIDNLVSENPNLVSKIQIGSSYEGRPLNVLKFSTGPNRPAFWIDTGIHSREW 184

  Fly   184 ITSATATWLINEFLT--STDELVRDLAENHDWYIVPVLNVDGFVYTHEKDRMWRKTRQPSEISSC 246
            :|.|:|.|...:.:|  ..|..:.:.....|..|..|.|.|||||||:.||||||||.|:..|.|
Frog   185 VTQASAVWFAKKIVTDFGKDPSLTNTLNQMDILIEIVTNPDGFVYTHKSDRMWRKTRSPNSGSLC 249

  Fly   247 IGADPNRNYDSHWMENEGASSNPCAEDYGGPKPFSEPEIQAMSEFVISIKDKINVLLAFHSYSQL 311
            :|.|||||:|:.: ...|:|||||.|.|.|....||||::|:.:||.| ...|...::.|||||:
Frog   250 VGTDPNRNWDAGF-GGPGSSSNPCTETYRGRAAHSEPEVKAIVDFVKS-HGNIKGFVSIHSYSQM 312

  Fly   312 LLSPYGHTKEEFPPNFDDMMEVAKAYGDAVESLPYGTVYRYGSAAGILYPASGATIDWAYNEQGV 376
            ||.|||:|.... |:.|::..|:|....|:.|| |||.|.|||....:|.|||.||||.|| ||:
Frog   313 LLFPYGYTNTRV-PDHDELNAVSKKAITALASL-YGTAYTYGSIISTIYQASGGTIDWTYN-QGI 374

  Fly   377 EISYTIEFRDTGRYGFILPPVHIIPNAEEALIGIAALLEKCKD 419
            :.||:.|.||||||||.||...|||.|||..:.:..|:|..:|
Frog   375 KHSYSFELRDTGRYGFALPANQIIPTAEETWLALTILIEHTRD 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416	16/77 (21%)
CG7025	NP_609133.2	M14_CP_A-B_like	123..416	CDD:199844	132/294 (45%)
cpa1	NP_001107681.1	Propep_M14	27..99	CDD:280416	16/78 (21%)
		MpaA	28..402	CDD:225421	151/385 (39%)
		M14_CPA	119..418	CDD:133081	135/304 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	243	1.000	Domainoid score	I2170
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	271	1.000	Inparanoid score	I2931
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm9413
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.070