DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7025 and Cpa5

DIOPT Version :9

Sequence 1:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_001002808.2	Gene:	Cpa5 / 408212	RGDID:	1303098	Length:	436	Species:	Rattus norvegicus

Alignment Length:	420	Identity:	144/420 - (34%)
Similarity:	238/420 - (56%)	Gaps:	35/420 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VLAQGASFGQDERLRYDNYSVYKVKFETQAQRSILRKL-AEDRENFRLWH-EAKDELHL-MLSPG 75
            :||  .::||   :.:....|.:|..:.:.|.|:||.| .:..:....|. .|:..|.: |..|
  Rat    27 ILA--VAWGQ---VNFTGDQVLRVLAKNEKQLSLLRDLEIQKPQKVDFWRGPARPSLPVDMRVP- 85

  Fly    76 AFGEL---ETEIQKTNVTAELFISNVQELIDSEEAA-----NLKASRDGTFGWTKYNSLAEIYAW 132
             |.||   :..::...:...:.|.::|.|:|.|..|     .|:.|.:| |.::.|::|.|||.|
  Rat    86 -FSELPSVKAYLKSHGLAYSVMIKDIQVLLDEERDAMARSRRLERSTNG-FSYSSYHTLEEIYNW 148

  Fly   133 LDDILAAYPTITESFIVGQSYEGRTIRGIKISYKS-NNPGVLIESNIHAREWITSATATWLINEF 196
            :|:.:|.:..:.....:|:|:|.|:|..:|.|... |...:.|::.||:|||||.||..|:..:.
  Rat   149 IDNFVAEHSNLVSKIHIGKSFENRSILVLKFSTGGPNRTAIWIDTGIHSREWITHATGIWISQKI 213

  Fly   197 LT--STDELVRDLAENHDWYIVPVLNVDGFVYTHEKDRMWRKTR--QPSEISSCIGADPNRNYDS 257
            :.  |.|.:::.:....|.:|..|.|.|||.:||..:|:|||.:  ||..:  |:|.|.|||:.:
  Rat   214 VNAYSKDHVLKKVLNTMDIFIEIVTNPDGFAFTHSMNRLWRKNKSIQPGIV--CVGVDLNRNWRT 276

  Fly   258 HWMENEGASSNPCAEDYGGPKPFSEPEIQAMSEFVISIKDKINVLLAFHSYSQLLLSPYGHTKEE 322
            .:..| |::.|||:|.|.||.|.||||:.|:..|:.. ......:::.|||||:::.||||:.|.
  Rat   277 GFGGN-GSNKNPCSETYRGPAPESEPEVAAIVAFITG-HGNFKAMISIHSYSQMVMYPYGHSLEP 339

  Fly   323 FPPNFDDMMEVAKAYGDAVESL--PYGTVYRYGSAAGILYPASGATIDWAYNEQGVEISYTIEFR 385
            . ||..::.|:||   |||::|  .:|..|.:||.:..||.|||.|:|||| :.|::.:::.|.|
  Rat   340 V-PNHKELFELAK---DAVKALYKVHGMEYIFGSISTTLYSASGITVDWAY-DSGIKYAFSFELR 399

  Fly   386 DTGRYGFILPPVHIIPNAEEALIGIAALLE 415
            |||:|||:||...|:|.|||..:.:..:::
  Rat   400 DTGQYGFLLPASQIVPTAEETWMALRTIMK 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416	17/72 (24%)
CG7025	NP_609133.2	M14_CP_A-B_like	123..416	CDD:199844	115/300 (38%)
Cpa5	NP_001002808.2	Propep_M14	48..117	CDD:396700	17/70 (24%)
Cpa5	NP_001002808.2	M14_CPA	134..434	CDD:349442	116/305 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351678
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	262	1.000	Inparanoid score	I3014
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm8990
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.800