DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7025 and CG14820

DIOPT Version :9

Sequence 1:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_648060.1	Gene:	CG14820 / 38754	FlyBaseID:	FBgn0035718	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	423	Identity:	192/423 - (45%)
Similarity:	259/423 - (61%)	Gaps:	20/423 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 IVLALVVLAQGASFGQDERLRYDNYSVYKVKFETQAQRSILRKLAEDRE-NFRLWHEAK---DEL 68
            :|:.|..||:..     |::|||||.||.|:.:...|..:|.  .::|. ....|.||:   :..
  Fly     7 LVVGLFGLARSV-----EQVRYDNYKVYNVRIDDLEQFKLLH--TQERSLKLSSWREARHLGESS 64

  Fly    69 HLMLSPGAFGELETEIQKTNVTAELFISNVQELIDSEEAANLKASRDGTFGWTKYNSLAEIYAWL 133
            .:||.|......|:.:.|.|.|..|.|.|||..||::.......|.:    ||::::|.||||||
  Fly    65 DIMLPPEYQKTFESLLTKHNFTYNLKIDNVQTHIDAQRPKQRITSME----WTQFHTLEEIYAWL 125

  Fly   134 DDILAAYPTITESFIVGQSYEGRTIRGIKISYKSNNPGVLIESNIHAREWITSATATWLINEFLT 198
            |.|...||.|...|.:|.|||||.|||:|||||..||.|.|||||||||||||||.|:.|:|.|.
  Fly   126 DVIEDRYPDIVTPFTIGNSYEGRPIRGVKISYKEGNPAVFIESNIHAREWITSATITYFIDELLV 190

  Fly   199 STDELVRDLAENHDWYIVPVLNVDGFVYTHEKDRMWRKTRQPSE-ISSCIGADPNRNYDSHWMEN 262
            ..:..|||:|:|.||||:||||.|||.|:||.:|:|||:|.||: ...|||.|.|||:|..||..
  Fly   191 PRNPAVRDIAQNVDWYIIPVLNTDGFAYSHEVERLWRKSRLPSDPTGECIGTDLNRNFDYLWMLT 255

  Fly   263 EGASSNPCAEDYGGPKPFSEPEIQAMSEFV-ISIKD-KINVLLAFHSYSQLLLSPYGHTKEEFPP 325
             ||.|:||::.|.||.|.|:|||..::.:: .||.: .|.:.::.|||.|.:|||:|||..|||.
  Fly   256 -GAESDPCSQLYAGPSPESDPEISQLTAYINNSIPEGTIKIYISLHSYGQYVLSPWGHTALEFPE 319

  Fly   326 NFDDMMEVAKAYGDAVESLPYGTVYRYGSAAGILYPASGATIDWAYNEQGVEISYTIEFRDTGRY 390
            ::..||.|||.:.||:.. .||||:.|||:|..||..||:..:|||..:.::|.||||.||.|..
  Fly   320 HYPQMMHVAKGFSDALYR-RYGTVFTYGSSATTLYEVSGSGKEWAYAVKNIKIHYTIELRDKGEL 383

  Fly   391 GFILPPVHIIPNAEEALIGIAALLEKCKDLGYL 423
            ||:|||..|||.|.|...|...::...:::..|
  Fly   384 GFVLPPEDIIPVAREVTEGFVGMIAAAREIDIL 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416	19/70 (27%)
CG7025	NP_609133.2	M14_CP_A-B_like	123..416	CDD:199844	155/295 (53%)
CG14820	NP_648060.1	Propep_M14	31..100	CDD:280416	20/70 (29%)
CG14820	NP_648060.1	M14_CP_A-B_like	115..410	CDD:199844	155/296 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468814
Domainoid	1	1.000	251	1.000	Domainoid score	I2056
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	287	1.000	Inparanoid score	I2817
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm6559
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
	11	10.800