DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7025 and CG4017

DIOPT Version :9

Sequence 1:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_609309.1	Gene:	CG4017 / 34296	FlyBaseID:	FBgn0032143	Length:	424	Species:	Drosophila melanogaster

Alignment Length:	434	Identity:	161/434 - (37%)
Similarity:	254/434 - (58%)	Gaps:	33/434 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LPIVLALVVLAQGASFGQDERLRYDNYSVYKVKFETQAQRSILRKLAEDRENFRLWHEAKDELHL 70
            |.::|::.:|.    |...||.|:|||.||:|......|...||.|..:.|:..:    .:.|||
  Fly     4 LLLLLSVNILI----FCLAERQRFDNYKVYRVSPVKANQLEGLRSLEANSEDALV----LNNLHL 60

  Fly    71 -----MLSPGAFGELETEIQKTNVTAELFISNVQE--LIDSEEAANLKASRDGTFGWTKYNSLAE 128
                 :::|...|.....::..:::.||..:|.|.  .:|.|..|:.. .|...:.|::|:.|.:
  Fly    61 GPTDFLVAPDFDGTFLKLVKDLDLSPELIDANAQTSLSLDIEPIADAN-RRSDDYSWSEYHELND 124

  Fly   129 IYAWLDDILAAYPTITESFIVGQSYEGRTIRGIKISY---KSNNPGVLIESNIHAREWITSATAT 190
            .:.|:.:::..||.:...|:.|||||||.:.|::|::   ::....:.:|:.:||||||..||||
  Fly   125 THRWMQNLVGKYPDVVSVFVAGQSYEGRELLGLRINHNDGRAEKQSIFLEAGMHAREWIGPATAT 189

  Fly   191 WLINEFLTSTDELVRDLAENHDWYIVPVLNVDGFVYTHEKDRMWRKTRQPSEISSCIGADPNRNY 255
            :..||.|:|..:.:.:||.::.|||:|..|.||:||||:.:|||||||.|.: .:|:|.|||||:
  Fly   190 YFANELLSSQQQEIMNLARSYVWYILPHANPDGYVYTHKTNRMWRKTRSPQD-KNCVGTDPNRNW 253

  Fly   256 DSHWMENEGASSNPCAEDYGGPKPFSEPEIQAMSEFVISIKDKINVLLAFHSYSQLLLSPYGHTK 320
            |.||.| .||||:||:|.|.|||.|||||:|.:|:|:.|:.:.:.:.|:.||:|||||.|||||
  Fly   254 DFHWRE-VGASSDPCSESYAGPKAFSEPEVQTLSQFLKSVPEPMFMFLSLHSFSQLLLYPYGHT- 316

  Fly   321 EEFPPNFDDMMEVAKAYGDAVESLP--YGTVYRYGSAAGILYPASGATIDWAYNEQGVEISYTIE 383
            ...|.|...:.::   :..||.::.  |||.|..|:....:|||:|:::||||....|:.|:|.|
  Fly   317 SALPENHRQLEQI---FNTAVGAMKRRYGTRYTGGNVYDAIYPAAGSSMDWAYGVLNVKYSFTYE 378

  Fly   384 FRDTGRY----GFILPPVHIIPNAEEALIGIAALLEKCKDL-GY 422
            .|.:| |    ||.||...|||..:|....:..:::....: ||
  Fly   379 LRPSG-YSFWTGFRLPAAQIIPTGQETTDSLVEMIKAAAQIEGY 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416	15/73 (21%)
CG7025	NP_609133.2	M14_CP_A-B_like	123..416	CDD:199844	127/301 (42%)
CG4017	NP_609309.1	Propep_M14	30..97	CDD:280416	15/70 (21%)
CG4017	NP_609309.1	M14_CP_A-B_like	119..415	CDD:199844	127/302 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467037
Domainoid	1	1.000	224	1.000	Domainoid score	I1450
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	239	1.000	Inparanoid score	I2114
Isobase	1	0.950	-	0	Normalized mean entropy	S1851
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm6559
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
	13	12.780