DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7025 and CG18585

DIOPT Version :9

Sequence 1:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_001260213.1	Gene:	CG18585 / 34041	FlyBaseID:	FBgn0031929	Length:	422	Species:	Drosophila melanogaster

Alignment Length:	419	Identity:	231/419 - (55%)
Similarity:	310/419 - (73%)	Gaps:	5/419 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 IVLALVVLAQGASFGQDERLRYDNYSVYKVKFETQAQRSILRKLAEDRENFRLWHEAKD---ELH 69
            ::..||.|..........:.||||:.|||:..:.:.|.:.:.|:.|..:.:.:|.|..:   ::.
  Fly     6 LLATLVALTSAGILKDSPKERYDNFRVYKLTIQNKIQLAAIEKIGELTKKYNIWKEYDERSRQID 70

  Fly    70 LMLSPGAFGELETEIQKTNVTAELFISNVQELIDSEEAANLKASRDGTFGWTKYNSLAEIYAWLD 134
            :|:|||.....:..::..|:::||.|.||||.||.|:..  ..:...|||||||..|.||.||||
  Fly    71 IMVSPGELNHFQELLKFNNISSELMIENVQERIDEEQVT--PTADSATFGWTKYYELEEIEAWLD 133

  Fly   135 DILAAYPTITESFIVGQSYEGRTIRGIKISYKSNNPGVLIESNIHAREWITSATATWLINEFLTS 199
            :||.|||::||.||||:|||||||||||||:|:.|||:.||||||||||||||:|||.||:.|||
  Fly   134 EILNAYPSVTEEFIVGKSYEGRTIRGIKISHKAGNPGIFIESNIHAREWITSASATWFINQLLTS 198

  Fly   200 TDELVRDLAENHDWYIVPVLNVDGFVYTHEKDRMWRKTRQPSEISSCIGADPNRNYDSHWMENEG 264
            .|..||.||:|:||:|:||.|||||.|:|:|||||||||||...::|||||.|||:||:|::|.|
  Fly   199 EDADVRSLADNYDWHIIPVFNVDGFEYSHKKDRMWRKTRQPHATNACIGADANRNFDSYWLQNNG 263

  Fly   265 ASSNPCAEDYGGPKPFSEPEIQAMSEFVISIKDKINVLLAFHSYSQLLLSPYGHTKEEFPPNFDD 329
            ||.|||:|.:.|..|.||||.:|:.|::..|:|:|:|.::||||.|.||||||||.||||.|::|
  Fly   264 ASDNPCSETFAGDNPESEPEAKALVEYLTKIQDQISVYISFHSYGQYLLSPYGHTNEEFPENYND 328

  Fly   330 MMEVAKAYGDAVESLPYGTVYRYGSAAGILYPASGATIDWAYNEQGVEISYTIEFRDTGRYGFIL 394
            ::.:.||:.||:|:|||||||:|||.|.:||.|:|.::||.:||.|.:|.||||:||.|||||||
  Fly   329 ILTIGKAFADAIEALPYGTVYQYGSTADVLYVATGTSVDWVFNELGKKIGYTIEYRDKGRYGFIL 393

  Fly   395 PPVHIIPNAEEALIGIAALLEKCKDLGYL 423
            |||.||||.||.::|:.||:||.|:||||
  Fly   394 PPVQIIPNCEELMVGMLALIEKTKELGYL 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416	18/69 (26%)
CG7025	NP_609133.2	M14_CP_A-B_like	123..416	CDD:199844	188/292 (64%)
CG18585	NP_001260213.1	Propep_M14	34..105	CDD:280416	19/70 (27%)
CG18585	NP_001260213.1	M14_CP_A-B_like	122..415	CDD:199844	188/292 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468812
Domainoid	1	1.000	251	1.000	Domainoid score	I2056
eggNOG	1	0.900	-	-		E1_COG2866
Homologene	1	1.000	-	-		H37541
Inparanoid	1	1.050	287	1.000	Inparanoid score	I2817
Isobase	1	0.950	-	0	Normalized mean entropy	S1851
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm6559
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	P	PTHR11705
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
	14	13.780