DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7025 and cpb1

DIOPT Version :9

Sequence 1:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_001315354.1	Gene:	cpb1 / 322412	ZFINID:	ZDB-GENE-030131-1132	Length:	416	Species:	Danio rerio

Alignment Length:	417	Identity:	154/417 - (36%)
Similarity:	229/417 - (54%)	Gaps:	37/417 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LALVVLAQGASFGQDERLRYDNYSVYKVKFETQAQRSILRKLAEDRENFRLWHEAKDEL------ 68
            |..|.|.:..:|..|:        |.::|.......:|:|:|.| :.....|.....:|
Zfish     9 LVAVALCEPITFVGDK--------VLQLKPINDEHVTIIRELGE-KIKLDFWKPRSADLVSIDMT 64

  Fly    69 ---HLMLSPGA-FGELETEIQKTNVTAELFISNVQELIDSEEAANLKASRDGTFG--WTKYNSLA 127
               |:   |.| ...:.|.:|::::..::.|.|:||.:..:     ..:|..|.|  :|||||.|
Zfish    65 VDIHV---PAAQLAMVSTILQQSDMEVKVMIDNLQEAVKGQ-----MDNRSPTKGHDYTKYNSWA 121

  Fly   128 EIYAWLDDILAAYPTITESFIVGQSYEGRTIRGIKISYK--SNNPGVLIESNIHAREWITSATAT 190
            .|..|...|.:|.|.:.....:|.:|||||:..:||...  ||.|.|.::...|||||||.|...
Zfish   122 TINDWAISISSANPDLISRQSIGNTYEGRTMHLLKIGKNTGSNKPAVFMDCGFHAREWITHAFCQ 186

  Fly   191 WLINEFLTS--TDELVRDLAENHDWYIVPVLNVDGFVYTHEKDRMWRKTRQPSEISSCIGADPNR 253
            |.:||.:::  :|..:.:|.:..|::::||.|:||:.||..:||||||||..:..|||||.||||
Zfish   187 WFVNEAVSTYGSDPDMTNLLDRMDFFVLPVFNIDGYEYTWNRDRMWRKTRSKNSGSSCIGTDPNR 251

  Fly   254 NYDSHWMENEGASSNPCAEDYGGPKPFSEPEIQAMSEFVISIKDKINVLLAFHSYSQLLLSPYGH 318
            |:::.|. ..|||||||::.|.|..|.||.|.:.::.|:.:.|..|...|..||||||||.||.:
Zfish   252 NFNAGWC-TVGASSNPCSDTYCGSSPESEIESKNLANFIRTNKSVIKAYLTVHSYSQLLLFPYSY 315

  Fly   319 TKEEFPPNFDDMMEVAKAYGDAVESLPYGTVYRYGSAAGILYPASGATIDWAYNEQGVEISYTIE 383
             |.:...:..::|.|::....|:.|| |||.|..|..|..:|||:|.:.|||| :.||:.|||.|
Zfish   316 -KYDLAAHHSELMSVSQGAIAALRSL-YGTKYTSGPGAATIYPAAGGSDDWAY-DLGVKYSYTFE 377

  Fly   384 FRDTGRYGFILPPVHIIPNAEEALIGI 410
            .||.|||||:||...|.|..||.::.:
Zfish   378 LRDEGRYGFLLPESQIKPTCEETMLAV 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416	16/76 (21%)
CG7025	NP_609133.2	M14_CP_A-B_like	123..416	CDD:199844	127/292 (43%)
cpb1	NP_001315354.1	M14_CPB	112..412	CDD:199852	129/297 (43%)
cpb1	NP_001315354.1	Propep_M14	27..99	CDD:280416	16/75 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593430
Domainoid	1	1.000	251	1.000	Domainoid score	I2056
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm6559
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.680