DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7025 and Agbl2

DIOPT Version :9

Sequence 1:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_848870.2	Gene:	Agbl2 / 271813	MGIID:	2443254	Length:	862	Species:	Mus musculus

Alignment Length:	322	Identity:	65/322 - (20%)
Similarity:	103/322 - (31%)	Gaps:	142/322 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 QSYEGRTIRGIKISYKSNNP-------GVLIESNIHAREWITSATATWLINEFL-----TSTD-E 202
            :|..|.|:..:.|:..|..|       .|::.:.:|..|    :.::|::|.||     .|.| :
Mouse   390 RSLAGNTVYLLTITNPSRTPQEAAAKKAVVLSARVHPGE----SNSSWIMNGFLDFILSNSPDAQ 450

  Fly   203 LVRDLAENHDWYIVPVLNVDGFVYTHEKDRMWRKTRQPSEISSCIGADPNRNYDSHWMENEGASS 267
            |:||:   ..:.::|:||.||.:..:.:             .|..|.|.||:|.:...:     |
Mouse   451 LLRDI---FVFKVIPMLNPDGVIVGNYR-------------CSLAGRDLNRHYKTVLKD-----S 494

  Fly   268 NPCAEDYGGPKPFSEPEIQAMSEFVISIKDKINVLL--AFHSYSQ-------------------- 310
            .||              |......:..:.::..|||  .||.:|:
Mouse   495 FPC--------------IWYTKNMIKRLLEEREVLLYCDFHGHSRKNNIFLYGCHSNNRKHWLHE 545

  Fly   311 ----LLLSPYGHTKEEFPP-NFDDMMEVAKAYGDAVESLPYGTVYRYGSAAGILYPASGATIDWA 370
                |:||.....|..|.. ||            .|:....||               |..:.|
Mouse   546 RVFPLMLSKNAPDKFSFDSCNF------------KVQKCKEGT---------------GRVVMW- 582

  Fly   371 YNEQGVEISYTIEF----------RDTGRYGFILPPVHIIPNAEEALIGIAALLEKCKDLGY 422
              ..|:..|||:|.          |||          |.             .:|..|.|||
Mouse   583 --RMGIINSYTMESTFGGSTLGSKRDT----------HF-------------TIEDLKSLGY 619

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416
CG7025	NP_609133.2	M14_CP_A-B_like	123..416	CDD:199844	60/314 (19%)
Agbl2	NP_848870.2	Pepdidase_M14_N	231..358	CDD:375499
		M14_AGBL2-3_like	379..629	CDD:349478	65/322 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	669..692
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	704..728
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	750..836
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900