DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7025 and SPBC337.07c

DIOPT Version :9

Sequence 1:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_595408.1	Gene:	SPBC337.07c / 2541067	PomBaseID:	SPBC337.07c	Length:	497	Species:	Schizosaccharomyces pombe

Alignment Length:	423	Identity:	125/423 - (29%)
Similarity:	196/423 - (46%)	Gaps:	61/423 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 YDNYSVYKVKFETQAQRSILRKLAEDRENFRLWHEAKDELHLMLSPGAF----GELETEIQKTNV 89
            |:...|.::..|.:...|.:.:.|:. :|..:|....|.:.|.|....|    .:..::|...|:
pombe    73 YNEEIVVRLHLEEENNLSDILQKAQS-QNLDIWDYNFDHVDLRLKEENFDFWKSQYRSDILINNL 136

  Fly    90 TAELFISNVQELIDS--EEAANLKASRDGTFG-----------WTKYNSLAEIYAWLDDILAAYP 141
            |..||.|.|.:..:|  ...|.|:|..:|...           :..|.:|..|.:||..:.:.|.
pombe   137 TETLFESIVPDTTNSPFSTEAFLQAVENGHLNHEMFTSFTDIFFKSYQNLESINSWLRLMASLYK 201

  Fly   142 TITESFIVGQSYEGRTIRGIKISYK---------SNNPGVLIESNIHAREWI---TSATATW-LI 193
            .::|...||.:.|||||.|:|::.:         .|...::|:...||||||   :...|.| |:
pombe   202 DLSELVPVGITAEGRTILGLKLNGRHPSDNGEKIRNKKVIIIQGGSHAREWIGIPSVCYAAWQLL 266

  Fly   194 NEFLTSTDELVRDLAENHDWYIVPVLNVDGFVYTHEKDRMWRKTRQPSEISSCIGADPNRNYDSH 258
            .::  .:|..||.|.:..:|..:|||||||:.||...||:|.|.|||...|.|.|.    |.|::
pombe   267 AKY--DSDGHVRKLLDKFEWIFIPVLNVDGYEYTWSNDRLWSKNRQPLNNSECFGI----NLDAN 325

  Fly   259 WMENEGASSNPCAEDYGGPKPFSEPEIQAM----SEFVISIKDKINVLLAFHSYSQLLLSPYGHT 319
            |......:.:||:.:|||..||...|..|:    :|.:...:.|:...|..|||||.:|.||.:|
pombe   326 WAFGFNGNIDPCSNEYGGLSPFQANETMALFNLITESLSQEQKKVVGFLDVHSYSQSVLWPYAYT 390

  Fly   320 KEEFPPNFDDMMEVA------------KAYGDAVESLPYGTVYRYGSAAGILYPASGATIDWAYN 372
            .:.|||:.::..|:|            :.|......:||...:::       | ..|..|||.|.
pombe   391 CDLFPPDTENFEELAIGLVKELHRVNSRYYTYQQACIPYDGFHKH-------Y-LPGTAIDWVYF 447

  Fly   373 EQGVEISYTIEFRDTGRYGFILPPVHIIPNAEE 405
            ...|...:.|..||.|.||::||...|:|.|:|
pombe   448 AADVAWPFNIRLRDMGDYGYLLPAKQIVPTAKE 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416	16/70 (23%)
CG7025	NP_609133.2	M14_CP_A-B_like	123..416	CDD:199844	102/312 (33%)
SPBC337.07c	NP_595408.1	MpaA	42..479	CDD:225421	123/420 (29%)
SPBC337.07c	NP_595408.1	M14_CP_A-B_like_1	180..492	CDD:199869	102/315 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	158	1.000	Domainoid score	I1007
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		otm46992
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
TreeFam	0	0.000	Not matched by this tool.
	9	8.840