DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7025 and ZC434.9

DIOPT Version :9

Sequence 1:	NP_609133.2	Gene:	CG7025 / 34042	FlyBaseID:	FBgn0031930	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_001251356.1	Gene:	ZC434.9 / 172908	WormBaseID:	WBGene00013895	Length:	720	Species:	Caenorhabditis elegans

Alignment Length:	450	Identity:	132/450 - (29%)
Similarity:	226/450 - (50%)	Gaps:	45/450 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 NSLPIVLALVVLAQGASFGQDERLRYDNYSVYKVKF-ETQAQRSILRKLAEDRENFRLWHEAKDE 67
            |:|.:::.:...|..|....|:..::.....:.... :.:|.|.|..:...|.:.::...:....
Worm     8 NTLWLLILISAFAINAEIADDKPPKFQVLRAHATDVPQLKALRDIHERTQHDLDFWQTPSKVGHR 72

  Fly    68 LHLMLSPGAFGELETEIQKTNVTAELFISNVQELIDSEE-----AANLKASR----DG----TFG 119
            ..:|:.......|::.::.:|::.::.|.:|.:||..:|     .:||..|:    :|    .:|
Worm    73 ADIMVDEDRMEWLDSVLKNSNISYDVIIEDVGKLILEKEHGPPRFSNLLFSKRMHNEGGNRARYG 137

  Fly   120 WTKYNSLAEIYAWLDDILAAYPTITESFIVGQSYEGRTIRGIKIS---YKSNNPGVLIESNIHAR 181
            :.:|:|...|..|:.||...||...:.|.:|.:.|||.|:||||.   ::::.....|:..||||
Worm   138 FGEYHSYQTICDWMKDIERKYPDKAKVFTMGTTSEGRPIQGIKIGSQVWRNDKRIFWIDGGIHAR 202

  Fly   182 EWITSATATWLINEFLT--STDELVRDLAENHDWYIVPVLNVDGFVYTHE----KDRMWRKTRQP 240
            ||....||.|.|:..:.  :.|.|||...:..::||:||.|.||:.|:..    ..|:|||.|..
Worm   203 EWAAVHTALWFIDRLIADYNDDSLVRAAVDRLNFYILPVANPDGYEYSRSDVSPMIRLWRKNRAG 267

  Fly   241 SEISS--------CIGADPNRNYDSHWMENEGASSNPCAEDYGGPKPFSEPEIQAMSEFVIS--I 295
            .....        |.|.|.|||||.|:.|. |:|::.|:|.|.|...|||.|.::|.:|:.|  :
Worm   268 VVCKKDRWFRDRCCGGVDLNRNYDWHFGET-GSSTDKCSEIYQGSSAFSESETRSMRDFLTSSEL 331

  Fly   296 KDKINVLLAFHSYSQLLLSPYGHTKEEFPPNFDDMMEVAKAYGDAVESLPYGTVYRYGSAAGILY 360
            ..||:..:..|:|||:.:.||.|.::..|.:..::..|.:|...|:|: .|||.|::|:.:.|||
Worm   332 NGKIDAFITLHTYSQMWIHPYSHARKSVPADVAELQRVGRAAVAALEN-TYGTKYKFGTGSDILY 395

  Fly   361 PASGATIDWAYNEQGVEISYTIEFR------DTGRYGFILPPVHIIPNAEEALIGIAALL 414
            |::|.:.|||.....::..|.:|.|      |    ||||....:||.|:|...||..::
Worm   396 PSAGGSDDWAKGTLRIKYVYLLELRPGEDVWD----GFILDQHQLIPTAKETWNGIKVVI 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7025	NP_609133.2	Propep_M14	36..103	CDD:280416	10/67 (15%)
CG7025	NP_609133.2	M14_CP_A-B_like	123..416	CDD:199844	110/316 (35%)
ZC434.9	NP_001251356.1	Propep_M14	45..111	CDD:366995	11/65 (17%)
		M14_CP_A-B_like	141..454	CDD:349433	110/316 (35%)
		ShK	682..719	CDD:366702
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37541
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm4737
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.820